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Proteins One of the most important organic molecules Almost 50% dry weight of cells Composed of monomers known as amino acids Contains hydrogen, carbon, oxygen and nitrogen and a variable side chain (R) + R H3N – C – COOH Amino acids link together to form a polypeptide Amino acids link together to form a polypeptide Linear arrangement of different amino acids is known as its primary structure Amino acids link together to form a polypeptide Linear arrangement of different amino acids is known as its primary structure Because of chemical bonding and repulsion, the linear arrangement of amino acids begins to fold taking on one of two distinct shape: Alpha helix Beta pleated sheet Less common Random coil When the polypeptide folds into a threedimensional shape, it is called a protein The three-dimensional shape of a protein is called its tertiary structure Myoglobin Binds oxygen Found in the muscles Acts as a storage site for oxygen Makes up the dark meat in chicken If two or more polypeptide chains link to form a protein its called it quaternary structure Hemoglobin Binds oxygen in the lungs and transports it through out the body Helps to regulate blood pressure Shape of the protein is important for its function Ex. Insulin = 51 amino acids Shape of the protein is important for its function Ex. Insulin = 51 amino acids Types of Proteins Type Function Communication Cell signaling Ex. Hormones in the bloodstream Defense Protection from infection Ex. Antibodies in the bloodstream Structure Mechanical support Ex. Collagen in skin & keratin in hair/nails Storage Stores nutrients Ex. Albumin in egg whites Contractile Movement Ex. Actin and myosin in muscles Transport Carries other molecules Ex. Hemoglobin Hormones Chemical messengers Ex. Growth hormone stimulates bone growth Enzymes Speed up chemical reactions Ex. Catalase Just for fun facts: Your hair is composed of all -helix Spider webs are all -pleated sheets