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⢠In contrast, O-glycosidic bonds join sugars to each other or attach sugars to the hydroxyl group of an amino acid on a protein ⢠The glycosides that are important in medicine because of their action on the heart (cardiac glycosides) all contain steroids as the aglycone ⢠These include digitalis and ouabain, which are inhibitors of the Na+-K+ ATPase of cell membranes. Other glycosides include antibiotics such as streptomycin. 29
