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Transcript
Worksheet
7.3-7.4
Section 7.3 – Gene linkage and Mapping
1. What did Morgan conclude from his research on fruit flies?
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2. How was Mendel’s law of independent assortment inaccurate?
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3. What is a linkage map?
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4. How are the distances between genes determined for a linkage map?
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5. What is the relationship between the distance between two genes and the chance that they will be inherited
together?
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6. What is the difference between a wild type and a mutant type?
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7. Using the following cross over frequencies draw a linkage map:
Cross-Over
Frequencies
A-B
20%
B-C
5%
A-C
25%
A-D
7%
D-B
13%
D-C
18%
Linkage Map
SECTION 7.4 – HUMAN GENETICS AND PEDIGREES
8. Why can only females be carriers of sex-linked disorders?
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9. What is a pedigree?
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10. What is one major difference in pedigrees between autosomal and sex-linked genes?
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11. How does genetic inheritance follow similar patterns in all sexually reproducing organisms?
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12. Who can be carriers of autosomal disorders?
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13. Why can females, but not males, be carriers of sex-linked genetic disorders?
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14. What is a pedigree?
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15. How are phenotypes used in pedigree analysis?
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16. What information on a pedigree can tell you whether a gene is on an autosome or on a sex chromosome?
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17. Complete the chart to follow the logic necessary to fill out a pedigree for a sex-linked gene. Use XD and Xd for
the dominant and recessive X-linked genes, respectively.
Phenotype
Female - Recessive
Male - Recessive
Genotype
XD Xd
Phenotype
Female carrier
Normal male
Female carrier
Male with
recessive phenotype
Female with recessive phenotype
Normal male
Female with recessive phenotype
Male with recessive phenotype
Parental Genotype
Female
Male
Offspring Phenotype
Female
Male
18. What are two methods that are used to directly study human chromosomes?
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19. What does a karyotype show about chromosomes?
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20. What is a karyotype?
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