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Date: March 14, 2016 Happy Birthday Chloe, Aim #60: How does DNA store genetic information? Julia & Ella!!!!!! Do Now: Warm-Up Notebook Date Title of Activity No Warm-Up Today Page # HW: 1) All labs due Wednesday!! Please see me if you think you are missing any labs. 2) Human Phys. Unit 7b Packet due Friday (March 18th) • Don’t forget Castle Learning! • Human Phys Fridays!! Weekly Human Phys Review in Room 142 with yours truly 3) Genetics Test next Tuesday (p.5) & Wednesday (p.1 & p.7)!! Aim #60: How does DNA store the genetic information? DNA 1) What is DNA? Deoxyribonucleic acid Carries the instructions for cell activities Nucleic Acids Nucleotides DNA or RNA Phosphate Sugar Base Bacterial Transformation (Griffith’s Experiment) https://www.youtube.com/watch?v=4LU71ubTCZA 2) Griffith’s Experiment: Harmless strain of bacteria were “transformed” into a deadly strain and killed the mice. Griffith called the substance the “transforming factor”. 3) Avery’s Experiment: Was the transforming factor Protein or DNA? Heat treated deadly strain + harmless strain + protein destroying enzymes Transformed Bacteria Heat treated deadly strain + harmless strain + DNA destroying enzymes Bacteria did not Transform Concluded that DNA is the genetic material of the cell. 4) Hershey & Chase Experiment: Bacteriophage When only the phage protein coats were labeled, most of the radioactivity was detected outside the cell. When the phage DNA was labeled, most of the radioactivity was detected inside the cells. 5) What are these instructions? • GENES • How did we get our genes? 6) Where are genes found? Genes (Smallest) chromosomes nucleus (Largest) 7) What do our genes give us? Our characteristics or traits 8) How many genes do we have? 46 Thousands on ______ chromosomes 9) How does DNA carry the genes? • The structure of DNA allows it to carry the genetic code • It is a double helix made of repeating nucleotides 10) What is a nucleotide made of? 4 types Deoxyribose Subunits of DNA 11) What bases make up the DNA ladder rungs? • • • • Adenine (purine) Thymine (pyrimidine) Guanine (purine) Cytosine (pyrimidine) 12) How do the bases pair up? All …. Teachers Go …. Crazy 13) What holds the DNA base pairs together? Weak hydrogen bonds 3 Hydrogen Bonds 2 Hydrogen Bonds 14) What in the DNA is unique in all organisms? The base sequence 15) What part of DNA carries the genetic code? The base sequence holds the genetic code. Each organism has a different sequence of bases Let’s review Where is DNA found? What determines our traits? Genes Where are genes located? What part of DNA carries the genetic code? Amoeba Sisters DNA Structure & Function https://www.youtube.com/watch?v=_POdWsii7AI 1 Gene = 1 Protein ALL TEACHERS GO CRAZY SEMI CONSERVATIVE REPLICATION ONE OLD STRAND & ONE NEW STRAND