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Biologist ___________________________ Date ______________ Viruses 20-1 Discovery of Viruses • Ivanovski (1892) found the tobacco mosaic disease was found in __________ from infected plants. • Beijernick (1897) found small particles in this __________ and named them ________. • Stanley (1935) isolated __________ of tobacco mosaic virus. Inferred viruses were not truly __________. • A __________ is a nonliving particle made of proteins, nucleic acids, and sometimes lipids. Structure and Composition • Viruses are very small. Simple viruses contain only a _______ genes whereas the most __________ may have more than a 100 genes. • The protein coat surrounding a virus is called a __________. • Most viruses have proteins on their surface membrane or capsid that bind to receptor proteins on the __________ cell. • The __________ “trick” the cell to take the virus, or in some cases just its genetic material, into the cell. • Inside the cell, viral genes are __________ and may __________ the cell. • Most viruses infect only a very __________ kind of cell. • Plant viruses infect plant cells; most animal viruses infect only certain related species of animals; viruses that infect bacteria are called _____________________. Viral Infections • Inside living cells, viruses use their __________ information to make multiple copies of themselves. Some viruses replicate __________, while others initially persist in an __________ state within the host. Lytic Infections • In a __________ infection, a virus enters a bacterial cell, makes copies of itself and causes the cell to burst, or lyse. • The virus enters the cell and __________ reproduces and hijacks the cell to make copies of the cell till it bursts (lyses). Lysogenic Infection • An infection where a host cell is not immediately taken over is a __________ infection. • __________ is a bacteriophage’s DNA that becomes imbedded in the host’s DNA. • The viral DNA becomes embedded in the host and inactive until a __________ (radiation, heat, chemicals, etc.) and it then becomes active. A closer look at 2 RNA viruses • In humans, RNA viruses cause a __________ range of infections, form relatively mild colds to severe cases of HIV. • About_______ of viruses contain RNA rather than DNA. The Common Cold • __________ is engulfed inside a cell where viral proteins make new copies of viral RNA and in roughly 8 hours bursts the host cell. HIV • HIV is a __________. • A __________ is one that is copied from RNA to DNA instead of DNA to RNA. • First it makes a viral DNA copy of its RNA which inserts into the _______ of the host. • It can remain __________, but once activated it will begin to destroy all body systems used to fight __________ Viruses and Cells • All viruses are __________. • Viruses are NOT living because they don’t grow and develop, use __________ or respond to the environment. • BUT viruses do have structure, reproduce using a host cell, have _______________ and change over time.