* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Amino acids
Survey
Document related concepts
Protein design wikipedia , lookup
Structural alignment wikipedia , lookup
Bimolecular fluorescence complementation wikipedia , lookup
Protein purification wikipedia , lookup
Homology modeling wikipedia , lookup
Protein moonlighting wikipedia , lookup
Nuclear magnetic resonance spectroscopy of proteins wikipedia , lookup
Protein domain wikipedia , lookup
Protein folding wikipedia , lookup
Western blot wikipedia , lookup
Circular dichroism wikipedia , lookup
List of types of proteins wikipedia , lookup
Protein–protein interaction wikipedia , lookup
Protein mass spectrometry wikipedia , lookup
Intrinsically disordered proteins wikipedia , lookup
Transcript
Amino acids by Jana Burianová, Joe Kalivoda Amino acids classes Basic classes: • coded » essential » nonessential • uncoded • according to their capacity to interact with water • • • • Nonpolar Polar Acidic Basic Sources of A. A. • metabolism (most plants, microbes) • food (essential A. A.) Main funtions of A. A. A. A. are monomers for: • peptides (2 - 100 units of A. A.) • oligopeptides (2 – 10 A. A.) • polypeptides (10 – 100 A. A.) • proteins (100 & more) • • • • structure (simple, composite) form (fibrilar, globular) solubility (scleroproteins, albumins, histones, globulins) function (proteins of basic metabolism, specialized cells) Structure of: Peptid Protein Polypeptide bond • peptide bonds are amide linkages between the αcarboxyl group of one AA and the α-amino group of another AA Protein structure • primary (specific amino acid sequence; the order in which the amino acids are linked together (specified by genetic information) • secondary (Consists of several repeating patterns in a part of polypeptide chain α – helix, b – pleated sheet) • tertiary (unique three-dimensional conformation that globular proteins assume as a consequence of the noncovalent interactions between the side chains in their primary structure) • quarternary (Many proteins are composed of several polypeptide chains = subunits) Origin • • • • Biochemistry I doc.RNDr. Ivana Márová, CSc. Biochemie I doc.RNDr. Ivana Márová, CSc. Lesson 12 (R/studenti/3. ročník/odborná angličtina) www.mcdonalds.cz