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Transcript
Supplementary MBBS I (First) Professional
Examination 2014-15
Course Code: MBS103
Paper ID: S322208
Biochemistry -I
Time: 2 Hours 40 Minutes
Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support
your answer.
Part ‘B’
1.
Define and classify lipids with examples. Discuss digestion
of lipids.
(10)
2.
a)
b)
Write short notes on the following:
Significance of pentose phosphate pathway
Ketone bodies
(5x2=10)
3.
Define isoenzymes. Discuss the role of isoenzymes in
clinical diagnosis with suitable examples.
(10)
4.
Differentiate between:
B-DNA and Z-DNA
Starch and glycogen
a)
b)
(5x2=10)
Supplementary MBBS I (First) Professional Examination 2014-15
Roll No.
Student’s Name
Student’s Signature
Invigilator’s Signature
Course Code:MBS103
Paper ID: S322208
Biochemistry - I
Part ‘A’
Time: 20 Minutes
Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
Q.1
Following is not a branched chain amino
acid:
a)
Valine
b)
Leucine
c)
Isoleucine
d)
Lysine
Q.6
Hyperbolic oxygen dissociation curve is a
property of:
a)
Hemoglobin
b)
Myoglobin
c)
Methemoglobin
d)
Carboxy-hemoglobin
Q.2
Proteins targeted for destruction
eukaryotes are covalently linked to:
a.
Clathrin
b.
Pepsin
c.
Laminin
d.
Ubiquitin
Q.7
Secretion of gastric HCl is stimulated by:
a)
Secretin
b)
Pancreozymin
c)
Histamine
d)
Melatonin
Q.8
Q.3
Triple helix is found in:
a)
Cystine
b)
Collagen
c)
Pectin
d)
DNA
Which
body:
a)
b)
c)
d)
in
Q.4
Cyanide is toxic because it:
a)
Inhibits cytochrome C oxidase
b)
Forms cyanmethaemoglobin
c)
Inhibits ATP carrier in mitochondria
d)
Inhibits Na+-K+ ATPase
Q.5
All is true about glutathione except:
a)
It is a tripeptide
b)
It
converts
hemoglobin
to
methemoglobin
c)
It conjugates xenobiotics
d)
It scavenges free radicals and
superoxide ions
of the following is not a ketone
Acetoacetate
Acetoacetyl CoA
3-Hydroxybutyrate
Acetone
Q.9
All of the following are mitochondrial
reactions except:
a)
Transamination
b)
Ketone body formation
c)
Beta oxidation of fatty acids
d)
Krebs cycle
Q.10
Absence of carnitine will affect:
a)
Fatty acid synthesis
b)
Fatty acid oxidation
c)
Creatinine formation
d)
Urea synthesis
P.T.O.
Q.11
Q.12
Hexose
monophosphate
responsible for production of:
a)
Hexose
b)
NADH
c)
Ribose
d)
ATP
shunt
is
Phosphorylation of glycogen synthase:
a)
Increases synthesis of glycogen
b)
Decreases synthesis of glycogen
c)
Has no effect on glycogen synthesis
d)
Inhibits glycogenolysis
Q.13
UDP is a carrier of:
a)
Monosaccharides
b)
Fatty acids
c)
Nucleic acids
d)
Amino acids
Q.14
Chylomicrons are formed within:
a)
Intestinal lumen
b)
Enterocytes
c)
Adipocytes
d)
Lymphatic vessels
Q.15
Activity of amylase cannot convert starch
into:
a)
Maltotriose
b)
Limit dextrin
c)
Maltose
d)
Glucose
Q.16
Cytochrome p450 is present in:
a)
Mitochondria
b)
Golgi complex
c)
Endoplasmic reticulum
d)
Lysosome
Q.17
Glucose 6-phosphate deficiency leads to:
a)
Pernicious anemia
b)
Hemolytic anemia
c)
Glycogen storage disease
d)
Galactosemia
Q.18
Maple syrup urine disease results from
defect in metabolism of:
a)
Branched chain amino acids
b)
Acidic amino acids
c)
Basic amino acids
d)
Imino acid
Q.19
Blood level of free fatty acids increases in
following:
a)
b)
c)
d)
Q.20
High fat diet
Diet rich in carbohydrates
Starvation
Intake of cholesterol-lowering drugs
Lipoic acid is a component of:
a)
Lipoproteins
b)
Fatty acid synthetase complex
c)
Pyruvate dehydrogenase complex
d)
Electron transport chain