Download Karyotype Lab File

My Karyotype is letter _______
1. Is your person male or female? How do you know?
2. How many autosomes are present on your karyotype?
3. Can you identify any genetic disorder in your karyotype? If so, what?
Analysis
4. Suppose that karyotyping revealed that a person is not able to produce Enzyme A. The
enzyme is needed for metabolizing Protein B. Without the enzyme, the person will develop a
serious illness. How could the knowledge from this karyotype be helpful in preventing this
disease?
5. Different species have different numbers of chromosomes. For example, a dog has 78
chromosomes in each cell and a cat has 38. Could different species such as these mate and
produce fertile offspring? Why or why not?
6. Dogs and chickens both have 78 chromosomes per cell. Could we artificially breed these two
animals, and get a “dogen” or a “chickdog”? Why or why not?
Follow Up
Some genetic disorders, with their corresponding genotypes, are listed in the chart below. Use
your book to find the symptoms of each disorder. Decide if these disorders may be determined
using a karyotype, or if a chemical test is needed.
Disorder
Symptoms
Genotype
Clue for Diagnosis
Hemophilia
Recessive gene on X
chromosome.
Klinefelter’s
Syndrome
XXY
Tay-Sachs Disease
Recessive gene on
chromosome 15.
Cri-Du-Chat
Syndrome
Partial deletion of
chromosome 5.
10. How can homologous pairs be identified?
11. What is the major chromosomal difference between the gametes and the somatic cells (be
specific)?
12. The male determines the sex of the offspring. Explain this statement.
13. How many chromosome pairs are in a normal human cell?
14. Photographs taken during what stage in cell division would be easiest to karyotype?
15. How many chromosome groups are in the Denver Classification System? What relationship
exists between the number of a chromosome and its size?
16. What are the four centromere locations in a chromosome? Draw an example of each location
and label their correct name.
17. Think about looking at a karyotype for chromosomal vs. gene disorders. What is then wrong
with this statement, “If a disorder is inherited, a karyotype will show an abnormality.”