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Transcript
Rosemilande Pierre
03.06 Mutations
Analyzing the graph
Describe how mutation and sexual reproduction can leads to genetic variation in a population
Mutation leads to genetic variation, usually, when there is replacement of one existing nucleotide with
another and that leads to a heritable change in a certain phenotype.
Which appears to be more dangerous: The BRCI OR BRC2 Mutation?
There’s a somewhat higher risk for breast and ovarian cancer with BRCA1 mutations than with BRCA2
mutations but breast cancer in males is associated with BRCA2 mutation. In my opinions, they are
equally bad and I have yet to come across a published article that convinces me otherwise
Analyze a woman’s risk of dying of cancer if she carries mutated BRCI
Risk of dying depends on what type of cancer is present. It can be very treatable, or the patient who
tests positive for having the mutation might never develop the cancer.
Explain how breast-cancer genes are still present in the population despite cancer-related surgeries and
deaths.
Rosemilande Pierre
03.06 Mutations
How are breast cancer genes are still present in the population, despite cancer related surgeries and
deaths?
For a genetic mutation to be passed along to your offspring the mutation must exist in your
reproductive cells sperm and or egg. These are not removed by breast cancer surgery.
Most cases of breast cancer occur after the woman has had children, so the gene, if it is present, is
passed on to her children before she knows she knows that she as or will get cancer. She might also be a
carrier spreading the mutation, but she herself is not affected.