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NAME_____________________________ Endocrine System PART ONE: How Hormones Work 1. Using the list of terms, identify the glands in the diagram, and complete the following table. Adrenal glands Hypothalamus Ovaries Pancreas Parathyroid gland Pineal gland (draw this in) Pituitary Testes Thymus gland (draw this in) Thyroid gland Name of Gland Adrenal cortex Adrenal medulla Hypothalamus Ovary Pancreas Parathyroid Pineal gland Pituitary (anterior) Pituitary (posterior) Testes Thymus Thyroid Hormone(s) 2. Write either “peptide hormone” or “steroid hormone” on the line above each diagram. Using the list of terms. pLace an appropriate word or phrase on the lines within each diagram. cyclic AMP, hormone receptor, hormone receptor complex, protein synthesis _______________________ _______________________ 3. Control of hormone release. Often the release of a hormone is dependent upon the blood level of the substance it is controlling. When the level of a substance increases, generally this causes the hormone secretion to __________________. This is an example of _______________ feedback. In other instances, ________________hormones oppose each other’s actions, thus regulating the target substance in the body. PART TWO: Hypothalamus and Pituitary Gland 4. Write “AP” beside the statements that apply to the anterior pituitary and “PP” beside the statements that apply to the posterior pituitary. a. b. c. d. e. _______ _______ _______ _______ connected to hypothalamus by nerve fibers connected to hypothalamus by blood vessels secretes hormones produced by hypothalamus controlled by releasing-hormones produced by hypothalamus 5. To show why the anterior pituitary is sometimes called the master gland, complete this table. Anterior Pituitary Produces TSH ACTH Gonadotropic hormones Female Male Gland Controlled Hormone Produced by Gland 6. What causes the hypothalamus to stop producing releasing-hormones and the anterior pituitary to stop producing its hormones? PART THREE: Thyroid and Parathyroid Glands 7. Match the conditions in the key with the phrases that follow. KEY: cretinism, exophthalmic goiter, simple goiter, myxedema Hypothyroidism (choose more than one): _______________________________________ Hyperthyroidism: ________________________________________________________ Hypothyroidism since birth: ________________________________________________ Hypothyroidism in the adult: ________________________________________________ Lack of iodine: __________________________________________________________ 8. Match the items in the key with the phrases that follow. KEY: Ca++ in bones, Ca++ in blood a. b. c. d. e. f. _______________ calcitonin present _______________ mistaken removal of parathyroids during a thyroid operation _______________ PTH present _______________ postmenopausal women who no longer produce estrogen _______________ osteoporosis _______________ child with tetany PART FOUR: Adrenal Glands have two parts 9. What hormones are produced by the adrenal medulla and what effect do they have on the body? What triggers the release of hormones from the adrenal medulla? 10. Distinguish between cortisol and aldosterone by writing “YES” or “NO” on each line. Cortisol Aldosterone Controlled by ACTH Glucocorticoids Mineralocorticoid Relieves stress Na+/K+ balance Amino acids -- glucose Controlled by angiotensin II 11. Indicate whether these symptoms are indicative of Addison disease or Cushing syndrome by writing “AD” or “CS” beside each description. a. b. c. d. e. f. g. h. _______ cannot handle bodily stress _______ cannot maintain blood glucose level _______ tendency toward diabetes mellitus _______ low blood pressure because of a low blood sodium level _______ high blood pressure because of a high blood sodium level _______ edema because of too much sodium in system _______ bronzing of skin _______ thin arms and legs; enlarged trunk PART FIVE: Pancreas Produces Two Hormones 12. Write the word “insulin” or “glucagon” on the appropriate arrow. Glycogen -------------- glucose molecules Storage in liver ------------- in the blood 13. Are these statements true (T) or false (F)? a. ___ All persons with diabetes mellitus have to take insulin. b. ___ Persons who have to take insulin to control diabetes have faulty receptors for insulin. c. ___ Diet can control diabetes even in persons who have to take insulin daily. PART SIX: Other Endocrine Glands 14. The pineal gland produces the hormone ____________ that helps regulate ___________. The ovaries produce ___________ and _____________ that function in the menstrual cycle and during pregnancy. The testes produce ______________ that influences production of _____________ and secondary sexual characteristics. 15. Match the items in the key to the phrases that follow. KEY: acromegaly, osteoporosis, diabetes insipidus, Cushing disease, diabetes mellitus, Addison disease, exophthalmic goiter Enlarged thyroid and bulging eyes: thyroid: Bronzing of skin: adrenal cortex: (two disorders) Weak bones: pancreas: Enlarged bones: posterior pituitary: Sugar in the urine: 16. PART SEVEN: Working together: Match the organ systems with the correct descriptions. _____ Integumentary system _____ Nervous system _____ Respiratory system _____ Urinary system _____ Lymphatic system _____ Reproductive system _____ Muscular system _____ Circulatory System _____ Skeletal system _____ Digestive system a. b. c. d. e. f. g. h. i. j. Lymphatic vessels pick up excess tissue fluid; immune system protects against infections. Bones provide protection for glands; store Ca++ used as second messenger. Kidneys keep blood values within normal limits so that transport of hormones continues. Stomach and small intestines produce hormones. Gas exchange in lungs provides oxygen and rids body of carbon dioxide. Hypothalamus is part of endocrine system; nerves innervate glands of secretion Gonads produce sex hormones. Muscles help protect glands. Skin helps protect endocrine glands. Blood vessels transport hormones; blood services glands; heart produces atrial natriuretic hormones.