Download D. Transfer of activated acetaldehyde to

BB 451/551 Exam 1
Name______________________________
THIS IS A PRACTICE EXAM I PUT TOGETHER TO SHOW THE FORMAT OF
EXAMS I WILL USE THIS TERM. PLEASE NOTE THAT I PULLED QUESTIONS
FROM MANY SOURCES, SOME OF WHICH WE HAVE TALKED ABOUT AND
SOME OF WHICH WE HAVEN’T
I WILL NOT ANSWER QUESTIONS ABOUT THE PRACTICE EXAM. IF YOU
HAVE QUESTIONS, YOU MAY USE YOUR BOOK OR OTHER BOOKS TO
ANSWER THEM
Section 1 __________
Section 2 __________
Section 3 __________
Total
__________
Do not open the exam until you are instructed to begin
BB 451/551 Exam #1, Page 1 of 6
Section I: The statements in this section can be completed by any of the lettered
responses following it. Each statement may have more than one answer that is
correct, one answer that is correct, or no answers that are correct. Students should
clearly circle only those responses that complete the sentence to make a correct
statement. Points will be awarded for each circled response that makes a correct
statement and for each uncircled response that makes an incorrect statement. For
example, the practice question below has three correct answers (b,c,d). You would
receive four points if you circled ‘b’,’c’, and ‘d’. You would receive one point if you
circled ‘a’ and ‘b’. You would receive no points if you circled only ‘a’. If we have
uncertainty about whether or not an answer is marked, it will automatically be
counted as a wrongly answered question. Be clear in your markings.
Practice question #A: Oregon State University
A. is a Bolivian factory
B. is located in Corvallis, Oregon
C. has a mascot named Benny Beaver
D. has students from all over the world.
1. In a cell where electron transport is tightly coupled to oxidative phosphorylation,
A. Oligomycin will stop electron transport
B. Oligomycin will stop oxidative phosphorylation
C. 2,4 dinitrophenol (DNP) has been added.
D. The rate of oxygen consumption is related to the amount of ATP production.
2. In the pyruvate dehydrogenase system
A. TPP serves as the terminal electron acceptor
B. Yeast use oxidative decarboxylation when no oxygen is available.
C. E1 catalyzes the transfer of electrons to FADH2
D. Transfer of activated acetaldehyde to lipoamide creates a disulfide
3. In the electron transport system (ETS),
A. Electrons travel in pairs until they reach complex IV
B. Rotenone blocks passage of electrons through complex III
C. Oxygen is the terminal electron acceptor
D. Complexes I, III, and IV all pump protons as electrons pass through them.
4. With respect to the transport systems across the lipid bilayer,
A. Antiports transfer molecules in opposite directions
B. ATP is involved in facilitated diffusion
C. ATP is required for active transport
D. The sodium-glucose pump is electrogenic
5. Ceramides
BB 451/551 Exam #1, Page 2 of 6
A.
B.
C.
D.
Don’t have a glycerol backbone
Contain one fatty acid
Are converted to cerebrosides by addition of a single sugar
Don’t have a phosphate
Section II: 1. Each sentence below in this section is missing a word or phrase to
complete it. Fill in the blank as appropriate to complete the sentence with a correct
statement. Each correctly filled in blank below will be awarded two points.
1. The common molecule discussed in class that all steroids are derived from is known
as _______________________.
2. What molecule discussed in class has the effect of broadening the transition
temperature of a lipid bilayer? _______________________.
3. The first gate to open in nerve transmission is the ______________________ gate.
4. Name one non-ionic molecule discussed in class that is transported against a
concentration gradient (from low to high) _____________________.
5. What pump discussed in class is important for balancing cellular osmotic pressure?
_______________________.
6. Transamination of oxaloacetate yields what molecule? _______________________.
(I’m looking for a name here)
7. The structure and name of the molecule produced in the citric acid cycle as a result of
oxidative decarboxylation of alpha-ketoglutarate is
__________________________________________________ (four points)
8. The name of the enzyme of the citric acid cycle that catalyzes the most energetically
UNFAVORABLE reaction is _______________________.
BB 451/551 Exam #1, Page 3 of 6
9. An acetyl-CoA is labeled with carbon 14 (14C) on both carbons and combined with
oxaloacetate that has carbon 12 (12C) in the first reaction of the citric acid cycle. This
starts cycle number one of the citric acid cycle. On which turn of the citric acid cycle will
14CO2
first be produced? _______________________.
10. What do flipases catalyze? _______________________.
11. Name one enzyme found in the glyoxylate cycle, but not the citric acid cycle.
_______________________.
12. Name two amino acids that can readily be converted to citric acid cycle
intermediates _______________________ and _______________________
13. Draw the structure of the molecule produced in the citric acid cycle reaction that
yields GTP _______________________.
14. What enzyme catalyzes the only substrate-level phosphorylation in the citric acid
cycle? _______________________.
15. Name the biological uncoupler (in brown fat) discussed in class
_______________________.
16. What function does the biological uncoupler in #15 provide to the body?
_______________________.
BB 451/551 Exam #1, Page 4 of 6
17. In F1 spheres, which of the three conformations discussed in class is responsible for
releasing the newly made ATP? _______________________.
18. During oxidative phosphorylation, into what cellular compartment is the newly
synthesized ATP released? _______________________.
19. The name of the coenzyme in the pyruvate dehydrogenase complex that acts as an
“electron sink” is _______________________.
20. Increasing saturation has what effect on the melting point of fatty acids?
_______________________.
21. The group of membrane proteins that give rise to the blood types of erythrocytes
are known as the _______________________.
22. Valinomycin is a molecule that provides what kind of transport across membranes?
_______________________.
23. What is the Standard Reduction Potential good for measuring?
_______________________.
Section III: Matching. Each term on the left has a phrase or term on the right which
best describes or matches it. Place the letter of the term/phrase on the right in the
blank before the term on the left that it best matches. Only one letter is appropriate
in the blank. Note that there are more terms on the right than there are blanks, so not
every term on the right has a best match. Terms on the right may be used once, more
than once, or not at all. If we cannot read your writing or if you put two letters in any
blank on the left, your answer will be counted wrong automatically. Each correctly
matched pair is worth two points.
____ 1.
____ 2.
____ 3.
____ 4.
____ 5.
Gramicidin
Cerebroside
Cyanide
Citrate
Fat
A. Triacylglycerol
B. Sphingomyelin
C. F0 stalk site
D. Active transporter
E. Malate dehydrogenase inhibitor
BB 451/551 Exam #1, Page 5 of 6
____ 6. Glycerophospholipid
____ 7. Spectrin
____ 8. Cytochrome c
____ 9. Malate
____ 10. Alanine
____ 11. FADH2
____ 12. Cristae
____ 13. Fluorocitrate
____ 14. Acetaldehyde
____ 15. Lipoamide
F. Mitochondrial shuttle molecule
G. Anaerobic electron acceptor
H. Contains two or more sugars
I. Transamination product
J. Contains six carbons
K. Contains disulfide bonds
L. Phosphatidyl choline
M. Complex IV inhibitor
N. Made from alpha-ketoglutarate
O. Ionophore
P. Coenzyme
Q. Contains iron
R. Neurotransmitter
S. Aconitase inhibitor
T. Contains a sugar
U. Cytoskeletal component
BB 451/551 Exam #1, Page 6 of 6