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INFECTIOUS DISEASE WHAT ARE INFECTIOUS DISEASES • TINY MICROBES SUCH AS BACTERIA AND VIRUSES WHICH GET INTO YOUR BODY AND MULTIPLY IN LARGE NUMBERS • FORCES OF NATURE OR EVIL DEEDS • DISCOVERED AROUND 1680 – ANTONI VAN LEEUWEHOEK • BACTERIA, FUNGI, PROTOZOA, VIRUSES, AND PRIONS (REFERRED TO THEM AS ANIMAL-CULES) Not a microorganism MECHANISMS OF INFECTION • FACTOR ONE • VIRULENCE – THE ORGANISMS ABILITY TO CAUSE DISEASE • FACTOR TWO • THE NUMBER OF ORGANISMS WHICH INVADE THE BODY • FACTOR THREE • RESISTANCE – ABILITY TO FIGHT OFF INFECTION INVASION • INVASION • INFLAMMATION – SWELLING AND REDNESS • TOXINS • MICROORGANISMS INVADE TISSUE AND RELEASE TOXINS • AS BLOOD PASSES THROUGH INFECTED TISSUES THE TOXINS ARE PICKED UP AND DISTRIBUTED THROUGHOUT THE BODY • MO TRAVELS TO A SPECIFIC AREA OF BODY (CNS)……ZIKA VIRUS RESISTANCE TO INFECTION • IMMUNE SYSTEM • WHITE BLOOD CELLS • MACROPHAGES • LYMPHOID TISSUE • TWO FUNCTIONS • ENGULFING AND DESTROYING AGENTS • PRODUCING ANTIBODIES RESISTANCE • NEUTROPHILS – TYPE OF WBC • MOBILE UNITS FORMED IN BONE MARROW • PROVIDE RAPID AND POTENT DEFENSE • SURROUND AND KILL MO RESISTANCE • MACROPHAGES • LARGE SLOW MOVING • RESIDE IN BONE MARROW, LIVER, SPLEEN, AND BLOOD • KILL ORGANISMS SURVIVING THE NEUTROPHILS RESISTANCE • MACROPHAGES • INFLAMMATION • MACROPHAGES WITH THE WBC WILL KILL OFF INVADING MO • PUS – RESULT OF THE DEAD MACROPHAGES AND WBC LYMPHOCYTES Attack organisms directly T CELL Form antibodies that attach to the surface of MO marking it for destruction B CELL TYPES OF INFECTIOUS AGENTS BACTERIA VIRUSES • SIMPLE, ONE-CELLED ORGANISMS • MOST NUMEROUS LIFE FORM – NOT A MO • MOST ARE HARMLESS • NEED A HOST TO SURVIVE • PASS BODY DEFENSES OR NORMAL DEFENSES ARE WEAKENED • PATHOGENIC ALMOST ALWAYS CAUSE INFECTION • EITHER DNA OR RNA • TAKE OVER HOST CONTROL CENTERS IN THE NUCLEUS • MAKE SPECIAL PROTEINS CAUSING SYMPTOMS & REPLICATE THEMSELVES VIRUSES • 1930’S – ELECTRON MICROSCOPE HELPED TO BETTER UNDERSTAND SHAPE AND COMPLEXITY • SPREAD THROUGH • DIRECT CONTACT • INDIRECT CONTACT • INSECT OR ANIMAL BITE • INFLUENZA VIRUS TYPES OF INFECTIOUS AGENTS FUNGI PARASITES • NON-GREEN PLANTLIKE • LIVE AND FEED ON ANOTHER ORGANISM • CAUSE ABOUT 30 DISEASES – MYCOSES • ENDOPARASITES – PROTOZOANS THAT LIVE WITHIN THE BODY (TAPEWORM) • EVOLVE SLOWLY • SKIN, HAIR, FINGERNAILS • ECTOPARASITES – LIVE ON BODY’S SURFACE (TICKS, FLEAS, LICE, WORMS) DISEASE CLASSIFICATION • TYPE OF ORGANISM CAUSING THE DISEASE • ORGAN SYSTEM THEY INFECT • SETTING IN WHICH THEY OCCUR • MOST COMMON ENCOUNTERED INVOLVE • SKIN • RESPIRATORY SYSTEM • GASTROINTESTINAL • UROGENITAL PREVENTION & TREATMENT • REDUCE EXPOSURE TO INFECTIOUS ORGANISMS • MAINTAINING BODY’S NATURAL DEFENSE SYSTEM • USING IMMUNIZATIONS • BETTER NUTRITION AND SANITATION