Download 1. Which is not a characteristic of cancer cells? a. They divide

1. Which is not a characteristic of cancer cells?
a. They divide excessively and invade other tissue
b. They can kill organisms
c. They exhibit density-dependent inhibition when growing in culture
d. They have escaped from cell-cycle controls
2. How do viruses contribute to cancer development?
a. Integrating genetic material into DNA of infected cells
b. A cancer starts from a virus
c. Replicated virus cells soon become cancer
3. What is the name of a cancer causing gene?
a. Oncogene
b. Tumor-suppressor gene
c. p53 gene
d. Ras gene
4. About how many changes must occur at the DNA level for a cell to become fully cancerous?
a. None
b. 1
c. 3
d. 6
5. If the abnormal cells of a tumor remain at the original site, the lump is called
a. Malignant tumor
b. Benign tumor
c. Metastasis
6. What is transformation?
a. The process that converts a normal cell to a cancer cell
b. The spread of cancer cells beyond their original site
7. Where can oncogenes be found?
a. Bacteria
b. Retro viruses
c. Fungi
8. What is a nickname for the p53 gene?
a. Guardian angel of the genome
b. apoptosis
9. What is a product of the Ras gene?
a. p53 gene
b. ras
10. What is the first sign of colorectal cancer?
a. Polyp
b. Benign tumor
c. Malignant tumor
11. List some of the differences between cancer cells and normal cells when placed in a culture.
12. Explain how cancer can be hereditary.
13.
Is this density dependant or density independent?
14.
How is this different from a normal cell cycle?
What is the difference between a proto-oncogene and an oncogene?
Answer Key
1. C
2. A
3. A
4. D
5. B
6. A
7. B
8. A
9. B
10. A
11. In a culture cancer cells are considered immortal. In contrast normal cells will divide 20-50
times in a culture age and die. Cancer cells do not exhibit density-dependent inhibition; normal
cells exhibit density –dependent inhibition
12. The fact that multiple genetic changes are required to produce a cancer cell, helps explain the
pre disposition to cancer, that runs in some families.
13. Density independent
14. Cell division is normally stimulated by external growth factors, not by oncogenes without
growth factors.
15. Oncogenes are cancer causing genes, and the normal cellular genes are called protooncogenes