Download 21:120:360 Biochemistry

Course Syllabus/Spring 2013
120:360 Biochemistry
INSTRUCTORS:
OFFICE/OFFICE
HOURS:
COURSE
LOCATION(S):
Gerald Frenkel
EMAIL:
[email protected]
321 Boyden/ by appointment
COURSE
WEBSITE:
Blackboard
MEETING TIME(S):MTH 8:30-9:50
Boyden 100
COURSE DESCRIPTION:
The objective of this course is to gain a deeper understanding of cell function through the study of the structure, function, and
metabolism of its component molecules.
PREREQUISITES:
Foundations of Molecular and Cellular Biology, Organic chemistry I & II
REQUIRED TEXT:
Voet, Voet & Pratt, Fundamentals of Biochemistry (Wiley)
LEARNING OBJECTIVES/GOALS:
Upon successful completion of this course, participants will have a deeper understanding of cell function by having gained
knowledge and insight into
1. the structures of its component molecules such as proteins, carbohydrates and lipids
2. the various functions of these molecules as enzymes, in membranes and in lipoproteins.
3. the metabolism of these molecules
4. the energy production and utilization mechanisms of the cell
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Course Syllabus/Spring, 2013
120:360 Biochemistry
SCHEDULE AND COURSE OUTLINE:
Class
number
Topic
Date
Readings in Voet
3rd Edition
Preparatory reading
11-19; Ch. 2 Chemistry
topics suggested for
review (see sheet)
1
1/24
Amino acids
Ch. 4
2
1/28
Proteins I
91-93;101-103
3
1/31
Proteins II
125-140
4
2/4
Proteins III
146-150; 156-160; 168172;177-180
5
2/7
Proteins IV
181-197
6
2/11
Lipids
246-254;260-263
7
2/14
Lipoproteins
678-685
2/18
Lecture Exam 1
8
2/21
Carbohydrates
220-231
9
2/25
Enzymes I
322-327; 364-375
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10
2/28
Enzymes II
375-383
11
3/4
Enzymes III
386-390; 328-330
12
3/7
Enzymes IV
347-357
13
3/11
14
3/14
Glycolysis & fermentation I
486-504; 510-514
15
3/25
Glycolysis & fermentation II
504-510
3/28
Lecture Exam 2
16
4/4
Pyruvate dehydrogenase
570-576; 585
17
4/8
Citric acid cycle
567-570; 576-584
18
4/11
Fatty acid catabolism
685-690; 698-700
19
4/15
Amino acid catabolism
738-747
20
4/18
Oxidation/reduction reactions
Electron transport
469-474; 600-618
21
4/22
Electron transport, oxidative phosphorylation
22
4/25
Carbohydrate biosynthesis
552-559
Glycogen
532-536; 540-542; 545
– 552
23
Introduction to metabolism & bioenergetics
4/29
Fatty acid biosynthesis
24
5/2
Lecture Exam 3
5/6
Nucleotide biosynthesis
DATE OF FINAL EXAM: 5/15/13
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451-470
618-631
701-707; 520-521
40-42; 818-838
GRADING POLICY:
Your grade for this course will be determined based on the categories listed in the table below.
2 highest lecture exams
Final exam
TOTAL
35 points each
30 points
100
ATTENDANCE, MAKE-UP, AND LATENESS POLICY:
A make-up examination will be available for students who must miss a regularly scheduled exam for an officially approved
reason such as a religious holiday, illness or family emergency (see university guidelines). If you would like to request a
makeup for any exam, please notify me as soon as possible so that there is sufficient time for me to approve the request. Do
not assume you will be able to receive a makeup exam unless it is confirmed by me.
Please note: There will be no makeup exams, special assignments etc. to improve your grade.
Academic Dishonesty: The course has a zero tolerance policy for academic dishonesty, including plagiarism and cheating.
Instances of dishonesty will be punished by a zero on the assignment and consultation with the Academic Integrity Officers
to determine if further action is required. If you have any questions about what constitutes plagiarism or cheating, please
ask your instructors or refer to the academic integrity websites for Rutgers and NJIT:



http://academicintegrity.rutgers.edu/academic-integrity-at-rutgers
http://studentconduct.rutgers.edu/
http://www.njit.edu/academics/integrity.php
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