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Atoms and Molecules • All organisms are composed of energy and matter • All matter is composed of atoms • Elements are pure substances that contain only one type of atom and cannot be separated into simpler substances. • Atoms have a central core called the nucleus, which is composed of protons and neutrons that determine the atomic mass. The protons of an atom have a positive charge. Atoms and Molecules • Surrounding the nucleus are electrons which are negatively charged. • Atoms that have equal numbers of electrons and protons are neutrally charged. • Atoms that have gained or lost electrons have charge and are called ions. • Ions are very important human physiology and are involved in the electrical responses associated with nerve and muscle function. They are also important in the chemical reactions needed for life. Chapter 2 – The Body’s Chemical Makeup Atoms and Molecules • Chemical bonding occurs between atoms through the sharing or transferring of electrons. •Ionic bonds occur between oppositely charged ions and involve a transfer of electrons. •Ionic compounds are extremely strong and solids are high melting points. •Ionic compounds dissociate in water and solutions conduct electricity. Chapter 2 – The Body’s Chemical Makeup Atoms and Molecules •Molecular (or Covalent) bonds occur between molecules that “share” electrons. •Molecular compounds have lower melting points. •When placed in solution, molecules remain intact and do not conduct electricity. •Most biochemicals are molecular compounds. •Most involve only C, H, N, O, P, S Chapter 2 – The Body’s Chemical Makeup Atoms and Molecules •Hydrogen bonds – weak intermolecular forces between the partial positive hydrogen atom and a very electronegative element (O, N, F) •These are important bonds in the human body. •Hydrogen bonds play an important role in the shape of complex molecules such as proteins and nucleic acids. Chapter 2 – The Body’s Chemical Makeup Chemical reactions •Chemical reactions drive the human body. •3 Types of Reactions: •Synthesis •Decomposition •Exchange (we learned these as single & double replacement reactions) •All reactions involve energy. Energy is either required or released. •Factors that effect reaction rates. Chapter 2 – The Body’s Chemical Makeup Acids and Bases Acid solutions have a high hydrogen ion concentration Base or alkaline solutions have a low hydrogen ion concentration A reaction between an Arrhenius acid and base will create a salt and water. Buffers prevent fluctuations in pH. Buffers are important in the human body. Chapter 2 – The Body’s Chemical Makeup water •Water is essential for life and has specific roles in the body •Water is a polar covalent moleculecharges are not distributed equally throughout the molecule. Chapter 2 – The Body’s Chemical Makeup water •Water is required for: •Stabilizing body temperature- remember heat capacity of liquid water is 4.18 J/goC (Does anyone remember the relationship of this to food calories?) •Protection - water lubricates and cushions •Chemical Reactions- water is required for chemical reactions to take place. •Transport- soluble substances can be transported through the body when dissolved. Chapter 2 – The Body’s Chemical Makeup Other important inorganic compounds •O2 - respiration •CO2 – photosynthesis Chapter 2 – The Body’s Chemical Makeup Organic Compounds •Carbon covalently bonded to functional groups of other elements create the molecules necessary for life. •Functional groups •Carboxyl – COOH •Amino •Carbonyl •Methyl •Phosphate •Hydroxyl Chapter 2 – The Body’s Chemical Makeup Carbohydrates •Carbohydrates include sugars, starches and cellulose •The are the main molecules for energy storage and energy production •Some can be used as building materials. •Monosaccharides – simple sugars •Glucose, fructose •Disaccharides – consist of 2 monosaccharide units •Sucrose, lactose •Polysaccharides-made of repeating monosaccharide units linked together by glycosidic bonds. •Starch, glycogen, cellulose Chapter 2 – The Body’s Chemical Makeup Carbohydrates Chapter 2 – The Body’s Chemical Makeup Lipids •Fats and fat-like substances •Insoluble in water •Consist mostly of carbon and hydrogen (hydrocarbons) •Functions: •store energy •form cell membranes •building blocks of steroid hormones •Can be saturated or unsaturated Chapter 2 – The Body’s Chemical Makeup Lipids Chapter 2 – The Body’s Chemical Makeup Proteins •Macromolecules that are polymers formed from amino acid monomers •great structural diversity •many functions: •structure •enzyme catalysis •defense •transport •motion Chapter 2 – The Body’s Chemical Makeup Proteins Chapter 2 – The Body’s Chemical Makeup Nucleic Acids •DNA & RNA •Transmit hereditary information by determining what proteins a cell makes •Made of nucleotide monomers (a ribose or deoxyribose, a phosphate group(s), and a nitrogenous base) Chapter 2 – The Body’s Chemical Makeup Nucleic Acids Chapter 2 – The Body’s Chemical Makeup