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Mendel’s Genetics Gregory Mendel 1851 Gregory Mendel Mendel became a monastery priest, high school teacher, and gardener. He became fascinated with the diversity of his pea plants. Gregory Mendel Mendel discovered that there were “purebred” peas for each of the traits. In other words, there were round seeded plants that if bred with other round seeded plants always produced round seeds. Gregory Mendel Wrinkled seeded plants that with other wrinkled seeded plants always produced wrinkled seeds. Etc. Etc. Gregory Mendel The curious thing was what happened when two different “purebred” plants were bred together. Mendel’s Conclusions Mendel concluded a couple of things. 1. Heredity 2. Dominant vs. Recessive Traits 3. Two sets of “genes” 4. Hybrids Heredity Mendel concluded that when organisms such as peas reproduce, some traits from the parents can be passed on to offspring. Traits that can be passed on are considered heritable. For example, the color of a pea plant is determined by heredity. Being green is a heritable trait. Heredity Not all traits are heritable. For example, if a pea plant is dried out because it didn’t get watered, that has nothing to do with its parents. Dominance Mendel also concluded that the traits being passed on by parents can come in forms that are dominant or recessive. Dominant traits are able to somehow mask or hide recessive ones. For example, having round seeds is a dominant trait since a purebred round seeded pea plant crossed with a purebred wrinkled seeded plant produces only round seeded offspring. 2 Genes The challenge for Mendel was trying to come up with an explanation for why the second generation of a purebred cross began to produce offspring that showed the recessive trait once again. 2 Genes The answer came in the ratio. Nearly every time he performed his experiment, he found that ~25% of the F2 offspring had the recessive trait. That got him thinking about…. MATH!!! MATH!!! MATH!!! MATH!!! MATH!!! How can you explain it? 2 GENES! If the round plant has 2 dominant genes for being round. And the wrinkled plant has 2 dominant genes for being wrinkled. Then... In the first generation, every offspring would get a dominant and a recessive copy. MATH!!! But in the second generation, 1 out of every 4 offspring would get 2 recessive genes! Mendel showed that life is mathematical and that every individual must have 2 sets of each code or gene. Hybrids Mendel used the term hybrids for plants that must contain a dominant and a recessive gene that were able to produce both dominant and recessive offspring. Genetics DNA wasn’t known to have any effect on inheritance until 1943 so Mendel didn’t know how traits were passed on, he was only able to show the mathematical way it works with dominance and recessivity. Genetics To make it easier to write out the genes of an organism, scientists came up with a system of capital and lowercase letters. Capital letters are used to represent dominant genes. Lowercase letters are used to represent recessive genes. Genetics For example: Black fur in rabbits is dominant. This rabbit is a purebred, so its genotype is BB. A genotype is the genetic code. A phenotype is the way something looks. Genetics This white rabbit is albino. Albinism is a recessive trait. That means its genotype must be bb. What’s its phenotype? Genetics What would the offspring look like if these two rabbits bred? Genetics What would the offspring look like if these two rabbits bred? Why? Punnett Square The square Mendel came up with is called a Punnett Square. Punnett Square The square Mendel came up with is called a Punnett Square. Uh oh! 2 of these bunnies are allowed to breed. What color will their babies be? Why?