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Transcript
Hypothalamic-anterior-pituitary System
Hypothalamus
Hypophysiotropic Hormones
Gonadatropic
Releasing
Hormone
GnRH
Follicle
Stimulating
Hormone
&
Leutenizing
Hormone
Growth
Hormone
Releasing
Hormone
GHRH
FSH
&
LH
Gonads
Germ
cell
Development
Secrete hormones
Female
Male
Estrogen, TestosProgesterone
terone
Somatostatin
Growth Hormone
Release-Inhibiting
Hormone
SS
Thyrotropin
Releasing
Hormone
TRH
Dopamine / (PIH) Corticotropin
Prolactin
Releasing
Inhibiting
Hormone
Hormone
DA
Adrenocorticotropic
Hormone
Anterior
Pituitary
Growth
Hormone
Thyroid
Stimulating
Hormone
Liver and Many organs
Other cells And tissues
Secrete
IGF-1
(Insulin-like Protein synthesis,
Carbohydrate &
Growth
lipid
metabolism
Factor I)
Reprod. Reprod.
Long loop
system; system;
Negative
breasts, growth/
Feedback
growth/ develop;
exerted on
develop; Sex drive; hypothalamus,
influences influences (i.e., an increase
gametes. gametes.
in plasma GH
Results in
Inhibition of
GH secretion).
IGF-I also acts
directly on the
pituitary to inhibit
the stimulatory
effect of GHRH
on GH secretion.
CRH
TSH
Thyroid
Prolactin
Breasts
Breast
Secretes
Development and
Thyroxine (T4),
Milk production
Triiodothyronine
(in male may
(T3)
Facilitate
Reproductive func.)
Metabolic
rate; growth;
brain.
T3 is more
Active than
T4, but T4 is
secreted in much
larger amounts.
Most cells can
convert T4 to T3.
ACTH
Adrenal
Cortex
Secretes
Cortisol
Organic
metabolism;
response to
stress;
immune
system.