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Transcript
Hypothalamic-anterior-pituitary System Hypothalamus Hypophysiotropic Hormones Gonadatropic Releasing Hormone GnRH Follicle Stimulating Hormone & Leutenizing Hormone Growth Hormone Releasing Hormone GHRH FSH & LH Gonads Germ cell Development Secrete hormones Female Male Estrogen, TestosProgesterone terone Somatostatin Growth Hormone Release-Inhibiting Hormone SS Thyrotropin Releasing Hormone TRH Dopamine / (PIH) Corticotropin Prolactin Releasing Inhibiting Hormone Hormone DA Adrenocorticotropic Hormone Anterior Pituitary Growth Hormone Thyroid Stimulating Hormone Liver and Many organs Other cells And tissues Secrete IGF-1 (Insulin-like Protein synthesis, Carbohydrate & Growth lipid metabolism Factor I) Reprod. Reprod. Long loop system; system; Negative breasts, growth/ Feedback growth/ develop; exerted on develop; Sex drive; hypothalamus, influences influences (i.e., an increase gametes. gametes. in plasma GH Results in Inhibition of GH secretion). IGF-I also acts directly on the pituitary to inhibit the stimulatory effect of GHRH on GH secretion. CRH TSH Thyroid Prolactin Breasts Breast Secretes Development and Thyroxine (T4), Milk production Triiodothyronine (in male may (T3) Facilitate Reproductive func.) Metabolic rate; growth; brain. T3 is more Active than T4, but T4 is secreted in much larger amounts. Most cells can convert T4 to T3. ACTH Adrenal Cortex Secretes Cortisol Organic metabolism; response to stress; immune system.