Download Severe Combined Immunodeficiency (SCID)

Severe Combined
Immunodeficiency (SCID)
Severe Combined
Immunodeficiency (SCID)
What is SCID?
• Severe Combined Immunodeficiency,
otherwise known as SCID.
• SCID is a group of very rare-and
potentially fatal-inherited disorders
related to the immune system.
• SCID makes those affected highly
susceptible to life-threatening infections
by viruses, bacteria and fungi.
What is SCID?
• Severe Combined Immunodeficiency,
otherwise known as SCID.
• SCID is a group of very rare-and
potentially fatal-inherited disorders
related to the immune system.
• SCID makes those affected highly
susceptible to life-threatening infections
by viruses, bacteria and fungi.
Is SCID
Inherited?
Is SCID
Inherited?
Chromosome Location?
• There are several
types of SCID.
• The most common
form is caused by a
mutation in the
SCIDX1 gene located
on the X
chromosome.
Chromosome Location?
• There are several types of
SCID.
• The most common form is caused
by a mutation in the
SCIDX1 gene located on
the X chromosome.
Interesting Facts!
• One form of SCID became the first
human illness treated by human gene
therapy in 1990.
• About 1 out of every 100,000 babies is
born with SCID.
• SCID is sometimes called Bubble Boy
disease. In the 1970s, a boy named
David Vetter had to live in a plastic
bubble for 12 years because of SCID.
Interesting Facts!
• One form of SCID became the first
human illness treated by human gene
therapy in 1990.
• About 1 out of every 100,000 babies is
born with SCID.
• SCID is sometimes called Bubble Boy
disease. In the 1970s, a boy named
David Vetter had to live in a plastic
bubble for 12 years because of SCID.
Citations
• http://www.genome.gov/13014325
• http://learn.genetics.utah.edu/content/disorders/w
hataregd/scid/
IMAGES
• http://kidshealth.org/PageManager.jsp?dn=girlshea
lth&lic=175&cat_id=132&article_set=21836
• US national library of Health