Download Chap 19 - Iowa State University

Adam
Leader:
Biology 212
Course:
Developmental Genetics
Instructor: Emeka Kemdirim
Supplemental Instruction
Iowa State University
Date:
 The science of developmental genetics is concerned with understanding how gene
expression controls the process of development.
Chapter 19:
I.
Development is due to arrangement of cells and their differentiation called
_______________.
a. Organized along 3 axes in animals
i. Dorsoventral axis
ii. Anterior posterior axis
iii. Left right axis
Can you identify these 3 axes on the picture?
II.
Pattern formation depends on what?
III.
Fill out the different ways cells respond to positional information
i.
ii.
iii.
iv.
Molecular Mechanisms used to Convey positional information
i. ___________- molecules that convey positional information, promote cell
division/migration/differentiation and apoptosis.
IV.
1. Do morphogens convey positional information during High or Low
concentrations?
2. Explain what induction is?
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ii. We learned that Morphogens are a way to convey positioning but what is
the other way?
1. Each cell makes surface receptors called what? And what do these
enable cell to do?
V.
Phases of development in animal body (describe what occurs in each of the 4 phases)
i.
ii.
iii.
iv.
VI.
In normal oocte development products of the _______ gene is accumulated at the
anterior end and they later act as _________ causing development of anterior end of
the embryo.
VII.
________ cells supply the products of maternal effect gene (bicoid mRNA) to the
developing oocyte.
VIII.
The development of segments is controlled by ________ genes.
IX.
Explain the phenomenon colinearity rule.
X.
Stem Cells are undifferentiated cells that divide and supply cells to living organism.
Characteristics: i. Stem cells have capacity to _________.
ii. Daughter cells can differentiate into…..
a. A Fertilized egg is an example of what kind of stem cell? (think about how one
egg can produce all cells of an adult organism)
b. Embryonic stem cells are an example of what kind of stem cell?
c. Describe a multipotent stem cell:
d. Describe unipotent stem cell: