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Download Figure 1. A) The gut epithelium is a single layer of cells organized in
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New insight into how colon cancer arises B Differentiation A Villus Enterocyte Goblet cell Proliferation Enteroendocrine cell Transit-amplifying cell Stem cell Paneth cell Crypt Figure 1. A) The gut epithelium is a single layer of cells organized in highly folded structures called crypts and villi. At the base of the crypts, stem cells give rise to all the specialized cell types of the gut, essential for the digestive, secretory and immune functions. B) Intestinal stem cells shown in red (arrowhead) can be visualized by detecting gene products specifically expressed in the stem cells. References: http://research.lunenfeld.ca/rssnews/?page=New insight into how colon cancer arises http://www.nature.com/nature/journal/vaop/ncurrent/full/nature15382.html
