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What IS
This??
Question of the Day
Question: How would you describe DNA to a
kid?
Answer: … … …
Notes: DNA & RNA
DNA
•
•
•
•
Located in nucleus
Too large to leave nucleus
Made of nucleotides
Nucleotide has 3 parts:
– Deoxyribose sugar
– Phosphate
– Base: A, T, C, G
• Bases always bond in pairs
– A&T
– C&G
DNA
• Watson & Crick discovered structure of DNA
– DNA shape = double helix
– Received Nobel Prize
– Used pictures from Rosalind Franklin
James Watson
Francis Crick
Rosalind Franklin
Franklin’s Picture of DNA
DNA
DNA Replication
• DNA copied before mitosis and meiosis
• New DNA is identical
• Occurs during interphase
Growth
DNA Replication
Growth
DNA Replication
• Replication:
1. DNA unwinds & unzips
2. Nucleotides are attached with DNA polymerase and ligase
• New molecules are attached until anaphase
DNA Replication
RNA
•
•
•
•
Single stranded
Can leave nucleus
Made of nucleotides
Nucleotide has 3 parts:
– Ribose sugar
– Phosphate
– Base: A, U, C, G
• Bases always bond in pairs
– A&U
– C&G
RNA
• Used carry information outside of nucleus
• Like a photocopy of DNA
Lab: Berry Full of DNA
Berry Full of DNA
1.
2.
3.
4.
5.
6.
Put your strawberry in baggie
Mush 2 minutes
Add 10 mL of extraction buffer
Mush 1 minute
Filter with cheesecloth & funnel
Add ethanol
Personal DNA
Exit Ticket:
Would you want your DNA analyzed?
Why or why not?
Explain in detail using examples.