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Journal of Bacteriology
Journal of Bacteriology

... initiation of cortical cell division (6, 9, 14, 45, 56, 61). The common nodABC genes are involved in the synthesis of extracellular factors (48), one of which has recently been identified in R. meliloti (29). This factor is modified by host-specific nod gene products, resulting in effective nodules ...
Gene Section myeloid leukemia 1; aml1 oncogene)) Atlas of Genetics and Cytogenetics
Gene Section myeloid leukemia 1; aml1 oncogene)) Atlas of Genetics and Cytogenetics

... This article is an update of : AML1 (acute myeloid leukemia 1). RUNX1 (runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)). Atlas Genet Cytogenet Oncol Haematol.1997;1(2):59-61. This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2. ...
Section D - Prokaryotic and Eukaryotic Chromosome Structure
Section D - Prokaryotic and Eukaryotic Chromosome Structure

... B sigma factor dramatically increases the relative affinity of the enzyme for correct promoter sites. C almost all RNA start sites consist of a purine residue, with A being more common than G. D all promoters are inhibited by negative ...
Identifying Factors that Control Mechanoreceptor Neuron
Identifying Factors that Control Mechanoreceptor Neuron

... studied as a basic behavioral component in C. elegans since the organism’s entire genome has been mapped. Investigating mechanosensation is much more challenging in complex eukaryotes because the mechanosensing cells and their scarce transducing molecules are more difficult to isolate and observe (C ...
Regulation
Regulation

... → Decreases synthesis of enzymes • Positive gene regulation – Activator protein binds separate binding site near promoter → Enhance RNA polymerase activity • Regulon: multiple operons regulated by the same regulator. – >40 regulons identified in E. coli ...
Abnormalities of epidermal differentiation associated with
Abnormalities of epidermal differentiation associated with

... is involved. Viral D N A replication is detectable only in the suprabasal layers; however it appears likely that the viral episome is present within cells of the basal layer, where early gene products might act to interfere with the normal control of cell proliferation and differentiation (Pfister, ...
1. Interpreting rich epigenomic datasets
1. Interpreting rich epigenomic datasets

... links increases linearly with number of cell types • Can estimate number of non22 random links at any FDR • 30 cell types: 15,000 links ...
Supplementary Material PDF
Supplementary Material PDF

... Fig. S2. ChIP controls demonstrate the specificity of the Prdm1a antibody. (A-C) Prdm1a pulls down previously identified enhancers for MyHC (A,C) and MyLC (A) at 24 hpf and does not pull down the genomic regions Upstream 1 and 2 and Downstream 1 and 2 (distance from the MyHC transcription start sit ...
Gene Section ERCC3  (Excision  repair  cross-complementing 3)
Gene Section ERCC3 (Excision repair cross-complementing 3)

... initiation and NER and the role of TFIIH in NER might closely mimic its role in the transcription initiation process. In transcription initiation TFIIH is thought to be involved in unwinding of the promoter site to allowing promoter clearance. In the NER process TFIIH causes unwinding of the lesion- ...
Gene Regulation Notes
Gene Regulation Notes

... 18.2 Organization of a Typical Eukaryotic Gene • Associated with most eukaryotic genes are control elements, segments of noncoding DNA that help regulate transcription by binding certain proteins • Control elements can be proximal (close) to the gene, or distal (far from the gene, thousands of ...
Transcriptional profiling of wheat caryopsis development using
Transcriptional profiling of wheat caryopsis development using

... wheat caryopses was analyzed using cDNA arrays. Using a mixed model analysis of variance (ANOVA) method, 29% (2,237) of the genes on the array were identified to be differentially expressed at the 6 different time-points examined, which covers the developmental stages from coenocytic endosperm to ph ...
supplementary material
supplementary material

... For eQTL mapping, the combined results from PC-, cis- and trans-mapping detected most eQTLs found in SPA and many more. Methods which utilize multiple correlated etraits in some form (PC- and trans-mapping) exhibited a strong increase in the power of eQTL detection over SPA. For PC-mapping, 24% of ...
Characterization of Two Rice MADS Box Genes That Control
Characterization of Two Rice MADS Box Genes That Control

... Plants contain a variety of the MADS box genes that encode regulatory proteins and play important roles in both the formation of flower meristem and the determination of floral organ identity. We have characterized two flower-specific cDNAs from rice, designated OsMADS7 and OsMADS8. The cDNAs displa ...
Interpreting the prevalence of regulatory Snps in cancers and protein coding SNPs among non-cancer diseases using GWAS Association Studies
Interpreting the prevalence of regulatory Snps in cancers and protein coding SNPs among non-cancer diseases using GWAS Association Studies

... Hence it is known that concentrating on few SNP and genes showing strong association with the disease is not sufficient to understand the underlying disease mechanism, because there exists a chance that those biologically important genetic variants that have a small disease risk are might get overlo ...
Yeast whole-genome analysis of conserved regulatory motifs
Yeast whole-genome analysis of conserved regulatory motifs

... • Dozens of chromatin tracks • Understand their function • Reveal their combinations • Annotate systematically ...
Gene Section EXT1 (exostoses (multiple) 1) Atlas of Genetics and Cytogenetics
Gene Section EXT1 (exostoses (multiple) 1) Atlas of Genetics and Cytogenetics

... Two patients with multiple osteochondromas demonstrated a germline mutation combined with loss of the remaining wild type allele in three osteochondromas, supporting the Knudson's two hit model for tumour suppressor genes in osteochondroma development; these results indicate that in cartilaginous ce ...
4.11 Repro Biol 053 Reik NEW
4.11 Repro Biol 053 Reik NEW

... Figure 2 Effects of imprinted genes on resource acquisition by offspring6. Imprinted genes that are expressed from the maternally derived copy are in purple; those expressed from the paternally derived copy are in blue. a, Growth of the fetus — promoted by, for example, Igf 2, a paternally expressed ...
Protein expression in plastids Peter B Heifetz* and Ann Marie Tuttle
Protein expression in plastids Peter B Heifetz* and Ann Marie Tuttle

Supplemental Data Whorl-Specific Expression of
Supplemental Data Whorl-Specific Expression of

... activity as described previously [S3]. The patterns of whole-mount floral staining from at least six independent stable transformants for each construct were characterized. The number of transgenic lines examined for each construct is given in Figures 1 and 5. Wholemount tissues were mounted in 100% ...
open access - Max-Planck-Institut für Pflanzenzüchtungsforschung
open access - Max-Planck-Institut für Pflanzenzüchtungsforschung

Online Repository - Nederlands Tweelingen Register
Online Repository - Nederlands Tweelingen Register

... associated with variation in gene expression levels (ie. expression quantitative trait loci, eQTLs). First, a database of eQTLs associated with gene expression levels in cis (located < 1 Mb from gene boundaries) or trans (> 1 Mb away or in a different chromosome) was created from 16 published transc ...
Human Chromosomes - Speedway High School
Human Chromosomes - Speedway High School

... British geneticist Mary Lyon discovered that in female cells, one X chromosome is randomly switched off. This chromosome forms a dense region in the nucleus known as a Barr body. Barr bodies are generally not found in males because their single X chromosome is still active. ...
Chromatin-Remodeling and Memory Factors
Chromatin-Remodeling and Memory Factors

... mediated through specific states of the chromatin structure. Therefore, changes in the chromatin structure associated with activation and silencing of gene expression are of paramount importance during development. Here, we discuss recent findings on plant proteins involved in modifying, remodeling, ...
Conservation and Coevolution in the Scale
Conservation and Coevolution in the Scale

... Fraser, Wall, and Hirsh 2003). A recent study that dealt with several such relationships simultaneously demonstrated correlations between different measures of evolutionary conservation and various functional genomic parameters (Krylov et al. 2003). However, the findings of some of these evolutionar ...
Human Cytomegalovirus UL34 Early and late Proteins Are Essential
Human Cytomegalovirus UL34 Early and late Proteins Are Essential

... (day 6) results in very little viral gene expression by 8 days post-transfection, corresponding to the defect in viral replication. Some variations in transcript levels were seen when comparing the UL34 mutant HCMV BACs. Expression of only the late UL34 protein resulted in detectable levels of UL36 ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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