The RNAi mechanism
... • See which genes can be knocked out to effect tumor growth • Paper describing this: “RNA interference microarrays: High-throughput loss-offunction genetics in mammalian cells” available from pubmed From Gene To Bio Function, Fall 04 ...
... • See which genes can be knocked out to effect tumor growth • Paper describing this: “RNA interference microarrays: High-throughput loss-offunction genetics in mammalian cells” available from pubmed From Gene To Bio Function, Fall 04 ...
Hammond 1 Regulation of gene expression during flocculation in
... of ybgC to flocculation is probably indirect while both PM21 and PM29 specifically function in this differentiation process. Data also suggest that PM21 and PM29 are under FlcA regulation. ...
... of ybgC to flocculation is probably indirect while both PM21 and PM29 specifically function in this differentiation process. Data also suggest that PM21 and PM29 are under FlcA regulation. ...
Finding Clusters of Positive and Negative Coregulated Genes in
... The metabolism of all organisms is tightly controlled by internal and external conditions so that not all proteins are produced under all circumstances. Products which function 1-4244-1509-8/07/$25.00 ©2007 IEEE ...
... The metabolism of all organisms is tightly controlled by internal and external conditions so that not all proteins are produced under all circumstances. Products which function 1-4244-1509-8/07/$25.00 ©2007 IEEE ...
Silencing by nuclear matrix attachment distinguishes cell
... enabling the resolution of each fraction following nuclease digestion. In comparison, scaffold-attached DNA, SARs, are isolated in a similar manner using 25 mM LIS (lithium 3,5-diiodosalicylate). It is clear from both small scale (20) and genomic (19) studies that these differential isolation methods ...
... enabling the resolution of each fraction following nuclease digestion. In comparison, scaffold-attached DNA, SARs, are isolated in a similar manner using 25 mM LIS (lithium 3,5-diiodosalicylate). It is clear from both small scale (20) and genomic (19) studies that these differential isolation methods ...
Basic Science for Clinicians
... experimental protocol in cardiovascular research is to examine gene functions through the use of transgenic or genetargeted mice. Although clearly informative, it is becoming increasingly clear that such studies alone are not sufficient to explain complex processes such as arrhythmias, heart failure ...
... experimental protocol in cardiovascular research is to examine gene functions through the use of transgenic or genetargeted mice. Although clearly informative, it is becoming increasingly clear that such studies alone are not sufficient to explain complex processes such as arrhythmias, heart failure ...
Genetic and Epigenetic Aspects of Polyploid Evolution in Plants
... mosomes; the latter are the divergent chromosome sets originating from the different species making up the allopolyploid genome [Stebbins, 1947]. In addition to these 2 canonical forms of polyploidy, a continuum of cytotypic states is possible during meiosis. For example, there may be majority diso ...
... mosomes; the latter are the divergent chromosome sets originating from the different species making up the allopolyploid genome [Stebbins, 1947]. In addition to these 2 canonical forms of polyploidy, a continuum of cytotypic states is possible during meiosis. For example, there may be majority diso ...
PPT
... In our study, as the keywords are extracted from gene specific sentences but not from full abstracts, the number of keywords associated with each gene is small. Further, the frequency of occurance of most keywords ...
... In our study, as the keywords are extracted from gene specific sentences but not from full abstracts, the number of keywords associated with each gene is small. Further, the frequency of occurance of most keywords ...
How Genes and Genomes Evolve
... functional RNAs – Processing requires variety of small RNAs (90 – 300 nucleotides long) & their associated proteins ...
... functional RNAs – Processing requires variety of small RNAs (90 – 300 nucleotides long) & their associated proteins ...
Effects of increased concentrations of chloride on the expression of
... medium«, issued by Parvaneh Sheydaei, supervisor Assist. Prof. Akbar Norastehnia, Ph. D. ...
... medium«, issued by Parvaneh Sheydaei, supervisor Assist. Prof. Akbar Norastehnia, Ph. D. ...
Gene Section EXT1 (exostoses (multiple) 1) Atlas of Genetics and Cytogenetics
... Germline mutations in EXT1 are causative for hereditary multiple exostoses, a genetically heterogeneous autosomal dominant disorder; mutations include nucleotide substitutions (54%), small deletions (27%) and small insertions (16%), of which the majority is predicted to result in a truncated or nonf ...
... Germline mutations in EXT1 are causative for hereditary multiple exostoses, a genetically heterogeneous autosomal dominant disorder; mutations include nucleotide substitutions (54%), small deletions (27%) and small insertions (16%), of which the majority is predicted to result in a truncated or nonf ...
TimeClust: a clustering tool for gene expression time series
... Before starting the Temporal Abstraction algorithm [3], it is often useful to smooth the data in order to make the algorithm more robust to noise. To this end, the moving average smoother has been implemented in the TimeClust tool. It computes a new time series from the original one by substituting ...
... Before starting the Temporal Abstraction algorithm [3], it is often useful to smooth the data in order to make the algorithm more robust to noise. To this end, the moving average smoother has been implemented in the TimeClust tool. It computes a new time series from the original one by substituting ...
Induction of XIST expression from the human active
... The XIST gene is the only gene known to be expressed exclusively from the inactive X chromosome (8) and is localised to the smallest interval of the X chromosome required in cis for inactivation to occur (9,10). The XIST RNA, which is not translated, remains in the nucleus where it is associated wit ...
... The XIST gene is the only gene known to be expressed exclusively from the inactive X chromosome (8) and is localised to the smallest interval of the X chromosome required in cis for inactivation to occur (9,10). The XIST RNA, which is not translated, remains in the nucleus where it is associated wit ...
RNA Genes: Retroelements and Virally Retroposable microRNAs in
... nucleolar RNA (snoRNA), short interfering RNA (siRNA), microRNA (miRNA), other classes of small RNAs and longer RNA intermediates including complex patterns of interacting and overlapping sense and antisense transcripts from both coding and non-coding regions of genomic DNA [2, 3]. The small RNAs ar ...
... nucleolar RNA (snoRNA), short interfering RNA (siRNA), microRNA (miRNA), other classes of small RNAs and longer RNA intermediates including complex patterns of interacting and overlapping sense and antisense transcripts from both coding and non-coding regions of genomic DNA [2, 3]. The small RNAs ar ...
Comparison of Statistical Models for Affymetrix GeneChip
... Model-based estimators are superior to simple averaging Full model superior to reduced this does not necessarily mean that the mismatch probes are a good idea - but if they are present we should use them we have demonstrated this using both analytic considerations and experimental data a carefully d ...
... Model-based estimators are superior to simple averaging Full model superior to reduced this does not necessarily mean that the mismatch probes are a good idea - but if they are present we should use them we have demonstrated this using both analytic considerations and experimental data a carefully d ...
Appendix S1.
... pseudo, putative or hypothetical genes (genes that are non-functional or not protein-coding). Extensive literature search was done. Genes were given higher credits and corresponding prioritization if there were evidences for relevant biological functions, involvement as structural constituents or in ...
... pseudo, putative or hypothetical genes (genes that are non-functional or not protein-coding). Extensive literature search was done. Genes were given higher credits and corresponding prioritization if there were evidences for relevant biological functions, involvement as structural constituents or in ...
Eye Development
... The transcription factor Pax6 is possibly required for maintenance of lens competence in mice. Expressed from early stages in head ectoderm in a region which overlaps, but is wider than the area fated to form the lens. In chimeric mice that were a mixture of Pax6+/+ and Pax6-/- cells, the mutant cel ...
... The transcription factor Pax6 is possibly required for maintenance of lens competence in mice. Expressed from early stages in head ectoderm in a region which overlaps, but is wider than the area fated to form the lens. In chimeric mice that were a mixture of Pax6+/+ and Pax6-/- cells, the mutant cel ...
1 Supporting Materials and Methods Plasmid expression vectors
... to target all Cnc isoforms. The UAS-rasV12 transgene encodes Ras with the G12V mutation [9]. The UAS-cncC-RNAi, UAS-rasV12 double transgenic line was generated by crossing the lines containing each allele and was maintained as an UAS-cncC-RNAi / CyO, Dfd-YFP; UAS-rasV12 stock. To generate larvae for ...
... to target all Cnc isoforms. The UAS-rasV12 transgene encodes Ras with the G12V mutation [9]. The UAS-cncC-RNAi, UAS-rasV12 double transgenic line was generated by crossing the lines containing each allele and was maintained as an UAS-cncC-RNAi / CyO, Dfd-YFP; UAS-rasV12 stock. To generate larvae for ...
Gene Expression Profiles and Microarray Data Analysis - BIDD
... • Cells are different because of differential gene expression. • About 40% of human genes are expressed at one time. • Gene is expressed by transcribing DNA into singlestranded mRNA • mRNA is later translated into a protein • Microarrays measure the level of mRNA expression ...
... • Cells are different because of differential gene expression. • About 40% of human genes are expressed at one time. • Gene is expressed by transcribing DNA into singlestranded mRNA • mRNA is later translated into a protein • Microarrays measure the level of mRNA expression ...
View Poster - Technology Networks
... miRNAs are involved in tissue development and maintenance and, until now, miRNAs appeared to be absent altogether from unicellular organisms. This has often led to the speculation that miRNAs have co-evolved with multicellularity in plants and animals. In contrast, we found that miRNA precursors are ...
... miRNAs are involved in tissue development and maintenance and, until now, miRNAs appeared to be absent altogether from unicellular organisms. This has often led to the speculation that miRNAs have co-evolved with multicellularity in plants and animals. In contrast, we found that miRNA precursors are ...
