Genomic approaches for the understanding of aging
... up-regulated genes in Drosophila head include genes involved in the immune response and amino acid metabolism. Aging in another important tissue in Drosophila melanogaster, the thorax, also results in the induction of genes involved in the immune response (40). In addition, genes linked to cellular ...
... up-regulated genes in Drosophila head include genes involved in the immune response and amino acid metabolism. Aging in another important tissue in Drosophila melanogaster, the thorax, also results in the induction of genes involved in the immune response (40). In addition, genes linked to cellular ...
finding the genes that regulate development
... See the development of the fruit fly from egg cell to larva laid out in Fig. 18.19 An important point to note: Each segment in the embryo is individually recognisable. It is possible to see if the pattern has been altered (as in the two mutants illustrated below). But this is not only true of the ad ...
... See the development of the fruit fly from egg cell to larva laid out in Fig. 18.19 An important point to note: Each segment in the embryo is individually recognisable. It is possible to see if the pattern has been altered (as in the two mutants illustrated below). But this is not only true of the ad ...
-Chain Gene in Epididymis α Expression of the C4b
... and on the surfaces of blood cells and various epithelial cells. In the reproductive organs the distribution of membrane-associated complement regulators, such as decay-accelerating factor (DAF),2 membrane cofactor protein (MCP), and CD59, has been well characterized in humans (1– 6) and in guinea p ...
... and on the surfaces of blood cells and various epithelial cells. In the reproductive organs the distribution of membrane-associated complement regulators, such as decay-accelerating factor (DAF),2 membrane cofactor protein (MCP), and CD59, has been well characterized in humans (1– 6) and in guinea p ...
The microRNA, miR-29c, participates in muscle development
... differentiation and apoptosis[4–6]. The miR-29 family contains three members, miR-29a, miR-29b and miR29c[7], and they have similar expression patterns and biofunctions. MiR-29 can participate in many physiological and chemical processes. It has been reported that miR29a can inhibit apoptosis and pr ...
... differentiation and apoptosis[4–6]. The miR-29 family contains three members, miR-29a, miR-29b and miR29c[7], and they have similar expression patterns and biofunctions. MiR-29 can participate in many physiological and chemical processes. It has been reported that miR29a can inhibit apoptosis and pr ...
Spatially restricted domains of homeo-gene
... the tongue (Fig. 5). Posterior to the pharynx, Hox.5 transcripts were readily detected in the trachea and the lung (Fig. 4D) . Hox-L .4 transcripts were detected in the thyroid gland but, unlike Hox-1.5 transcripts, were not present generally in tissues that formed the floor of the pharynx (Fig. 48) ...
... the tongue (Fig. 5). Posterior to the pharynx, Hox.5 transcripts were readily detected in the trachea and the lung (Fig. 4D) . Hox-L .4 transcripts were detected in the thyroid gland but, unlike Hox-1.5 transcripts, were not present generally in tissues that formed the floor of the pharynx (Fig. 48) ...
Supplementary table I: Yeast strains Used in this study
... remains repressed producing pink/white sectoring in about 16-17% of the colonies, as indicated, despite the recruitment of lexA-VP16 to the HXK1 locus. Note that the lacop array separates ADE2 from the HXK1 promoter. ...
... remains repressed producing pink/white sectoring in about 16-17% of the colonies, as indicated, despite the recruitment of lexA-VP16 to the HXK1 locus. Note that the lacop array separates ADE2 from the HXK1 promoter. ...
Article Positive Selection Underlies Faster-Z
... effective population size. Recent work in birds suggests that Fast-Z of coding sequence is primarily due to relaxed purifying selection resulting from reduced relative effective population size. However, gene sequence and gene expression are often subject to distinct evolutionary pressures; therefor ...
... effective population size. Recent work in birds suggests that Fast-Z of coding sequence is primarily due to relaxed purifying selection resulting from reduced relative effective population size. However, gene sequence and gene expression are often subject to distinct evolutionary pressures; therefor ...
Chapter 18 Regulation of Gene Expression Multiple-Choice
... genes in eukaryotic cells? A) organization of the genes into clusters, with local chromatin structures influencing the expression of all the genes at once B) each of the genes sharing a common control element, allowing several activators to turn on their transcription, regardless of their location i ...
... genes in eukaryotic cells? A) organization of the genes into clusters, with local chromatin structures influencing the expression of all the genes at once B) each of the genes sharing a common control element, allowing several activators to turn on their transcription, regardless of their location i ...
Analysis of mRNA - quantitation (contd)
... – Nearly half of ORFs are of unknown function – About 25% of all ORFs are unique to a particular species! • Suggests that many new protein families remain to be discovered • Many new functions may be uncovered – Periodic re-evaluation of sequenced genomes is useful • Compare with newly acquired data ...
... – Nearly half of ORFs are of unknown function – About 25% of all ORFs are unique to a particular species! • Suggests that many new protein families remain to be discovered • Many new functions may be uncovered – Periodic re-evaluation of sequenced genomes is useful • Compare with newly acquired data ...
Ribosome stalls at trp codons, allowing 2+3 pairing Transcription
... Enzymes acting in pathway to produce tryptophan. Gene order correlates with order of reactions in pathway. ...
... Enzymes acting in pathway to produce tryptophan. Gene order correlates with order of reactions in pathway. ...
Altering gene expression by aminocoumarins: the role of DNA
... To obtain a more comprehensive overview on the effect of GyrB inhibition, and thus relaxation of supercoiling, we performed microarray analysis. Bacteria were grown to OD600 = 0.6 followed by one hour of incubation with or without novobiocin. Microarray analysis confirmed that recA and arlRS express ...
... To obtain a more comprehensive overview on the effect of GyrB inhibition, and thus relaxation of supercoiling, we performed microarray analysis. Bacteria were grown to OD600 = 0.6 followed by one hour of incubation with or without novobiocin. Microarray analysis confirmed that recA and arlRS express ...
Discovery of MLL1 binding units, their localization to CpG Islands
... Background: Mixed Lineage Leukemia 1 (MLL1) is a mammalian ortholog of the Drosophila Trithorax. In Drosophila, Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothin ...
... Background: Mixed Lineage Leukemia 1 (MLL1) is a mammalian ortholog of the Drosophila Trithorax. In Drosophila, Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothin ...
doc - Sol Genomics Network
... (pepper etc). BAC analysis shows that gene order is highly conserved between the sol species, even some (more complex) ordering is preserved in arabadopsis. ...
... (pepper etc). BAC analysis shows that gene order is highly conserved between the sol species, even some (more complex) ordering is preserved in arabadopsis. ...
Two enhancer regions in the mouse En-2 locus
... et al., 1991). In the adult, En-2 is strongly expressed in cells of the internal granular layer of the cerebellum. No expression is detected in the neighbouring Purkinje cells, whereas weak expression is detectable in cells of the molecular layer (Davis et al., 1988; Davis and Joyner, 1988; K. Mille ...
... et al., 1991). In the adult, En-2 is strongly expressed in cells of the internal granular layer of the cerebellum. No expression is detected in the neighbouring Purkinje cells, whereas weak expression is detectable in cells of the molecular layer (Davis et al., 1988; Davis and Joyner, 1988; K. Mille ...
Transcriptional profiling of interleukin-2
... Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence Supplementary Material ...
... Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence Supplementary Material ...
... injected must match the mature “trimmed” mRNA sequence for the gene and the interference could not be elicited by intron sequences. This implies that interference takes place after transcription, probably in the cytoplasm rather than in the cell nucleus (4) The mRNA was revealed to be targeted with ...
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... Carmen Birchmeier3 and James Briscoe1,† Monoaminergic neurons include the physiologically important central serotonergic and noradrenergic subtypes. Here, we identify the zinc-finger transcription factor, Insm1, as a crucial mediator of the differentiation of both subtypes, and in particular the acq ...
... Carmen Birchmeier3 and James Briscoe1,† Monoaminergic neurons include the physiologically important central serotonergic and noradrenergic subtypes. Here, we identify the zinc-finger transcription factor, Insm1, as a crucial mediator of the differentiation of both subtypes, and in particular the acq ...