Journal of Plant Physiology
... (Huang et al., 2004; Zhang et al., 2004a,b) also improved the tolerance of transgenic plants to various abiotic stress, such as high salinity, drought and low temperature conditions. Overexpression of AtEBP resulted in resistance to Bax-induced cell death and abiotic stresses such as hydrogen peroxi ...
... (Huang et al., 2004; Zhang et al., 2004a,b) also improved the tolerance of transgenic plants to various abiotic stress, such as high salinity, drought and low temperature conditions. Overexpression of AtEBP resulted in resistance to Bax-induced cell death and abiotic stresses such as hydrogen peroxi ...
Nkx5 genes in inner ear development and genome evolution
... Acampora, D., Mazan, S., Avantaggiato, V., Barone, P., Tuorto, F., Lallemand, Y., Brulet, P., and Simeone, A. (1996) Epilepsy and brain abnormalities in mice lacking the Otx1 gene. Nat. Genet. 14: 218-22 Acampora, D., Merlo, G. R., Paleari, L., Zerega, B., Postiglione, M. P., Mantero, S., Bober, E., ...
... Acampora, D., Mazan, S., Avantaggiato, V., Barone, P., Tuorto, F., Lallemand, Y., Brulet, P., and Simeone, A. (1996) Epilepsy and brain abnormalities in mice lacking the Otx1 gene. Nat. Genet. 14: 218-22 Acampora, D., Merlo, G. R., Paleari, L., Zerega, B., Postiglione, M. P., Mantero, S., Bober, E., ...
Gene silencing using a heat-inducible RNAi system in
... 1998). RNAi operates at post-transcriptional level, leading to sequence specific degradation of homologous mRNA in the cytoplasm. The mechanism involved is reliably initiated by double strand RNA (dsRNA) which is cleaved by an RNAse III like enzyme complex (Dicer) to produce small interfering RNAs ( ...
... 1998). RNAi operates at post-transcriptional level, leading to sequence specific degradation of homologous mRNA in the cytoplasm. The mechanism involved is reliably initiated by double strand RNA (dsRNA) which is cleaved by an RNAse III like enzyme complex (Dicer) to produce small interfering RNAs ( ...
Recombineering Hunchback identifies two conserved domains
... The Hunchback/Ikaros family of zinc-finger transcription factors is essential for specifying the anterior/posterior body axis in insects, the fate of early-born pioneer neurons in Drosophila, and for retinal and immune development in mammals. Hunchback/Ikaros proteins can directly activate or repres ...
... The Hunchback/Ikaros family of zinc-finger transcription factors is essential for specifying the anterior/posterior body axis in insects, the fate of early-born pioneer neurons in Drosophila, and for retinal and immune development in mammals. Hunchback/Ikaros proteins can directly activate or repres ...
Information Encoding in Biological Molecules: DNA and
... Catalog of software includes: • blat - Fast alignment of similar sequences. • autoSql - create SQL and C code for permanently storing a structure in database and loading it back into memory based on a specification file • ameme - Find motifs in DNA sequence. • 40 other command line programs for geno ...
... Catalog of software includes: • blat - Fast alignment of similar sequences. • autoSql - create SQL and C code for permanently storing a structure in database and loading it back into memory based on a specification file • ameme - Find motifs in DNA sequence. • 40 other command line programs for geno ...
pRSI17 Linearized shRNA Cloning and Expression Vector
... The HIV-based lentivector system is designed to maximize its biosafety features, which include: ...
... The HIV-based lentivector system is designed to maximize its biosafety features, which include: ...
Interfering RNA
... • what target regions are accessible for RNAi and provide for inhibition • showing of antisense targets across mRNA may be sufficient, but not all antisense targets are open to siRNA • intron targets may not be active for siRNA but may be for antisense – identify all elements claimed and their suppo ...
... • what target regions are accessible for RNAi and provide for inhibition • showing of antisense targets across mRNA may be sufficient, but not all antisense targets are open to siRNA • intron targets may not be active for siRNA but may be for antisense – identify all elements claimed and their suppo ...
Male-to-male transmission of X-linked Alport syndrome in a
... not the first time that a production of aneuploid embryos together with an increment of aneuploid sperm in the father has been detected.15 – 17 Moreover, the father of the proband presented with oligozoospermia, which has previously been related to augmented frequencies of sex chromosome disomies an ...
... not the first time that a production of aneuploid embryos together with an increment of aneuploid sperm in the father has been detected.15 – 17 Moreover, the father of the proband presented with oligozoospermia, which has previously been related to augmented frequencies of sex chromosome disomies an ...
Global Transposon Mutagenesis and a Minimal Mycoplasma Genome
... This data set is divided approximately equally between the two organisms. A total of 71% of the insertions were within genes in M. genitalium versus 61% in M. pneumoniae. This represents a substantial preference for intergenic insertion— because coding sequence constitutes 85% of the M. genitalium g ...
... This data set is divided approximately equally between the two organisms. A total of 71% of the insertions were within genes in M. genitalium versus 61% in M. pneumoniae. This represents a substantial preference for intergenic insertion— because coding sequence constitutes 85% of the M. genitalium g ...
Reconciling the many faces of lateral gene transfer
... delineates a continuous segment of transferred DNA containing one or more ORFs, and whose length is rounded to the nearest ~500 bp; different colours represent segments of transferred DNA identified by either or both methods. Despite several reasons why these procedures are expected to identify some ...
... delineates a continuous segment of transferred DNA containing one or more ORFs, and whose length is rounded to the nearest ~500 bp; different colours represent segments of transferred DNA identified by either or both methods. Despite several reasons why these procedures are expected to identify some ...
CONTROL OF THE ACTIVITY OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR
... cell through oxidative phosphorylation. This function is carried out by the electron transport chain (ETC), composed of five protein complexes (I to V), all of them anchored to the inner mitochondrial membrane, plus ubiquinone and cytochrome c acting as mobile electron carriers between complexes. Ea ...
... cell through oxidative phosphorylation. This function is carried out by the electron transport chain (ETC), composed of five protein complexes (I to V), all of them anchored to the inner mitochondrial membrane, plus ubiquinone and cytochrome c acting as mobile electron carriers between complexes. Ea ...
Identification of expressed sequences in the coffee - Funpec-RP
... Coffee researchers have benefited from the Brazilian Coffee Genome Project (PBGC), in which approximately 33,000 unigenes have been identified starting from 214,964 ESTs obtained from 37 cDNA libraries in different physiologic stages of Coffea arabica, C. canephora, and C. racemosa. These ESTs have ...
... Coffee researchers have benefited from the Brazilian Coffee Genome Project (PBGC), in which approximately 33,000 unigenes have been identified starting from 214,964 ESTs obtained from 37 cDNA libraries in different physiologic stages of Coffea arabica, C. canephora, and C. racemosa. These ESTs have ...
Wnt Genes Review - Stanford University
... and Varmus, 1982). But the numerous Writ genes isolated from diverse species in the past few years have now attracted unusual attention because of the dramatic developmental phenomena attributed to them. Ectopic expression of Writ genes induces axis duplication in frog embryos (McMahon and Moon, 198 ...
... and Varmus, 1982). But the numerous Writ genes isolated from diverse species in the past few years have now attracted unusual attention because of the dramatic developmental phenomena attributed to them. Ectopic expression of Writ genes induces axis duplication in frog embryos (McMahon and Moon, 198 ...
Introduction to the Analysis of Microarray Data
... consists of a glass slide on which thousands of distinct DNA sequences have been affixed. Each dot (or “feature”) on the slide represents the sequence of a different plant gene. After the unbound probe is washed away, a special slide scanner excites each feature on the array with a laser and measure ...
... consists of a glass slide on which thousands of distinct DNA sequences have been affixed. Each dot (or “feature”) on the slide represents the sequence of a different plant gene. After the unbound probe is washed away, a special slide scanner excites each feature on the array with a laser and measure ...
Adaptive Gene Expression Divergence Inferred from Population
... simulans and D. yakuba. This approach has the critical advantage that it does not confound expression divergence with sequence evolution across lineages. DNA polymorphism and divergence data allow one to directly test for both recent and recurrent directional selection on genes and noncoding regions ...
... simulans and D. yakuba. This approach has the critical advantage that it does not confound expression divergence with sequence evolution across lineages. DNA polymorphism and divergence data allow one to directly test for both recent and recurrent directional selection on genes and noncoding regions ...
Time-shift and inverse clustering of expression data finds new
... between genes. The current analysis of whole-genome expression data focuses on relationships based on global correlation over a whole time course, identifying clusters of genes whose expression levels simultaneously rise and fall. There are, of course, other potential relationships between genes, wh ...
... between genes. The current analysis of whole-genome expression data focuses on relationships based on global correlation over a whole time course, identifying clusters of genes whose expression levels simultaneously rise and fall. There are, of course, other potential relationships between genes, wh ...
Imprinted Genes and Human Disease
... sociated with these genes share a common motif. Second, we consider the nature and frequency of mutations of imprinted genes. We ask whether we should expect that imprinted genes are particularly fragile. That is, are they more likely to undergo mutation and/or are mutations of imprinted genes parti ...
... sociated with these genes share a common motif. Second, we consider the nature and frequency of mutations of imprinted genes. We ask whether we should expect that imprinted genes are particularly fragile. That is, are they more likely to undergo mutation and/or are mutations of imprinted genes parti ...
Supplemental File S9. Homologous Chromosomes
... present on the maternally and paternally inherited chromosomes for this autosomal chromosome pair in a normal individual? Explain. Answer 1-4: The maternal and paternal chromosomes inherited by each human individual are homologous: they encode the same array (order and number) of genes along their l ...
... present on the maternally and paternally inherited chromosomes for this autosomal chromosome pair in a normal individual? Explain. Answer 1-4: The maternal and paternal chromosomes inherited by each human individual are homologous: they encode the same array (order and number) of genes along their l ...
Epigenetics - Institute for Cancer Genetics
... non-coding RNAs, including small interfering RNA (siRNA), microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play important roles in gene expression regulation at several levels transcription, mRNA degradation, splicing, transport and translation (21). The main function of siRNAs and miRNAs is po ...
... non-coding RNAs, including small interfering RNA (siRNA), microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play important roles in gene expression regulation at several levels transcription, mRNA degradation, splicing, transport and translation (21). The main function of siRNAs and miRNAs is po ...
Chapter 16: Gene Regulation in Bacteria
... levels are high, tryptophan acts as a corepressor. It binds to the trp repressor and activates it. The complex can now bind to the trp operator site to inhibit transcription (See Figures 16.11A and B). The second mechanism by which the trp operon can be transcriptionally regulated is termed attenuat ...
... levels are high, tryptophan acts as a corepressor. It binds to the trp repressor and activates it. The complex can now bind to the trp operator site to inhibit transcription (See Figures 16.11A and B). The second mechanism by which the trp operon can be transcriptionally regulated is termed attenuat ...
Caspary T, Cleary MA, Baker CC, Guan XJ, Tilghman SM. Mol Cell Biol. 1998 Jun;18(6):3466-74. Multiple mechanisms of imprinting on distal mouse chromosome 7.
... parental copies of a gene. Although the precise mechanisms by which genomic imprinting occurs are unknown, the tendency of imprinted genes to exist in chromosomal clusters suggests long-range regulation through shared regulatory elements. We characterize a 800-kb region on the distal end of mouse ch ...
... parental copies of a gene. Although the precise mechanisms by which genomic imprinting occurs are unknown, the tendency of imprinted genes to exist in chromosomal clusters suggests long-range regulation through shared regulatory elements. We characterize a 800-kb region on the distal end of mouse ch ...
DNA-free CRISPR-Cas9 genome engineering in
... The CRISPR-Cas9 system permits researchers to quickly edit genes for functional protein knockout in mammalian, fish and plant genomes, among others, and consequently has dramatically transformed biological research. The CRISPR-Cas9 system requires exogenous Cas9 nuclease to be delivered into the cel ...
... The CRISPR-Cas9 system permits researchers to quickly edit genes for functional protein knockout in mammalian, fish and plant genomes, among others, and consequently has dramatically transformed biological research. The CRISPR-Cas9 system requires exogenous Cas9 nuclease to be delivered into the cel ...