Gene Section MUC17 (mucin 17, cell surface associated) in Oncology and Haematology
... Radiation hybridization mapping was performed using the GeneBridge4 radiation hybrid panel (Research Genetics, Huntsville, AL). Following hybridization, the MUC17 probe was detected in the panel of 93 independent human/hamster fusion clones with MUC17 specific primers, and data were analyzed using t ...
... Radiation hybridization mapping was performed using the GeneBridge4 radiation hybrid panel (Research Genetics, Huntsville, AL). Following hybridization, the MUC17 probe was detected in the panel of 93 independent human/hamster fusion clones with MUC17 specific primers, and data were analyzed using t ...
identifying parent-daughter relationships among duplicated genes1
... definition, the “probability of co-occurrence” and the “length of the region harboring the higher probability.” In our simple model, we assume that the probability of co-occurrence of a homologous gene between two genomes is different between regions of shared synteny (psyn) and regions outside shar ...
... definition, the “probability of co-occurrence” and the “length of the region harboring the higher probability.” In our simple model, we assume that the probability of co-occurrence of a homologous gene between two genomes is different between regions of shared synteny (psyn) and regions outside shar ...
Involvement of HLS1 in Sugar and Auxin
... grown in the dark did not form an apical hook, similar to hls1-1 (Supplementary Fig. S1). Furthermore, strong alleles of hls1 mutants such as hls1-1, hls1-7 and hls1-9 in the Columbia ecotype also showed increases in amylase activity and anthocyanin accumulation in Suc-supplied excised leaf petioles ...
... grown in the dark did not form an apical hook, similar to hls1-1 (Supplementary Fig. S1). Furthermore, strong alleles of hls1 mutants such as hls1-1, hls1-7 and hls1-9 in the Columbia ecotype also showed increases in amylase activity and anthocyanin accumulation in Suc-supplied excised leaf petioles ...
Regulation of CO2 fixation via the Calvin cycle in the facultative
... heterotrophic growth may exist. Evidence supporting this is presentedin chapters II, III and V. Biochemical and genetic evidence shows that X. flavus possessestwo FBPase enzyme forms (chapter III). The cloning and characterizationof two transketolasegenes (tkt, cbbn is describedin chaptersII and V. ...
... heterotrophic growth may exist. Evidence supporting this is presentedin chapters II, III and V. Biochemical and genetic evidence shows that X. flavus possessestwo FBPase enzyme forms (chapter III). The cloning and characterizationof two transketolasegenes (tkt, cbbn is describedin chaptersII and V. ...
Vital Genes in the Heterochromatin of
... genetic and molecular studies have shown that this ubiquitous component of eukaryotic chromosomes may perform important biological functions. In D. melanogaster, about 30 genes that are essential for viability and/or fertility have been mapped to the heterochromatin of the major autosomes. Thus far, ...
... genetic and molecular studies have shown that this ubiquitous component of eukaryotic chromosomes may perform important biological functions. In D. melanogaster, about 30 genes that are essential for viability and/or fertility have been mapped to the heterochromatin of the major autosomes. Thus far, ...
Gene Regulatory Network of Ikaros in T cell development and
... Ikaros is a master regulator of lymphogenesis, especially critical for lymphoid differentiation and maturation. Recurrent genomic lesions of Ikaros have been found associated with high risks of relapse of leukemia and poor outcome of therapy. However, it remains unclear about the gene regulatory net ...
... Ikaros is a master regulator of lymphogenesis, especially critical for lymphoid differentiation and maturation. Recurrent genomic lesions of Ikaros have been found associated with high risks of relapse of leukemia and poor outcome of therapy. However, it remains unclear about the gene regulatory net ...
A CONTRIBUTION TO AN UNDERSTANDING OF CROSSING
... the chromosomes remain unpaired in zygotene and pachytene, as DARLINGTON suggests, the chief contention of the early telosynaptists is supported in Oenothera, for the great bulk of the pachytene spireme would then be univalent. If,bn the other hand, the homologous segments are long and the greater p ...
... the chromosomes remain unpaired in zygotene and pachytene, as DARLINGTON suggests, the chief contention of the early telosynaptists is supported in Oenothera, for the great bulk of the pachytene spireme would then be univalent. If,bn the other hand, the homologous segments are long and the greater p ...
What Do You Mean, “Epigenetic”?
... 2010). Those in the field of genetics concerned with DNA methylation, chromatin activity states, chromosomal imprinting, centromere function, etc., predominantly use Holliday’s notion of epigenetics. They are interested in how expression patterns persist across different cells (mitosis) and generatio ...
... 2010). Those in the field of genetics concerned with DNA methylation, chromatin activity states, chromosomal imprinting, centromere function, etc., predominantly use Holliday’s notion of epigenetics. They are interested in how expression patterns persist across different cells (mitosis) and generatio ...
Key transcriptional regulators of the vasoprotective effects of shear
... Direct targets for KLF2 have also been identified, even though a consensus KLF2 binding sequence in promoters of target genes has not yet been identified. The general GC rich KLF binding site 5’-CACC-3’ seems not very specific and can in principle be bound by all 20-odd KLF family members, as well a ...
... Direct targets for KLF2 have also been identified, even though a consensus KLF2 binding sequence in promoters of target genes has not yet been identified. The general GC rich KLF binding site 5’-CACC-3’ seems not very specific and can in principle be bound by all 20-odd KLF family members, as well a ...
Article
... three nuclear localization signals, suggesting that it is linked to the transcriptional machinery (Luo et al., 1999). In general terms, the polycomb proteins may be thought to regulate, by hitherto unknown mechanisms, target genes involved in cell proliferation in the embryo and endosperm of develop ...
... three nuclear localization signals, suggesting that it is linked to the transcriptional machinery (Luo et al., 1999). In general terms, the polycomb proteins may be thought to regulate, by hitherto unknown mechanisms, target genes involved in cell proliferation in the embryo and endosperm of develop ...
Toxicity Mechanisms Identification via Gene Set
... Pathway analysis is one family of bioinformatic tools for toxicity mechanisms elucidation, which aims at pinpointing key functional gene groups and regulatory pathways evoked during the toxicant exposure under a given condition.12,13 Through shifting the focus from detecting differentially expressed ...
... Pathway analysis is one family of bioinformatic tools for toxicity mechanisms elucidation, which aims at pinpointing key functional gene groups and regulatory pathways evoked during the toxicant exposure under a given condition.12,13 Through shifting the focus from detecting differentially expressed ...
PDF
... pCR2.1-ACF1-flag using the Site-directed Mutagenesis Kit (Stratagene). The following pairs of oligonucleotides were used to delete the PHD1 or PHD2, respectively: PHD1F, 5⬘-ACCAATAAGTCATTAGTCGACGTAAAGAGTCTGGGTCTCAGC-3⬘; PHD1R, 5⬘-ACCCAGACTCTTTACGTCGACTAATGACTTATTGGTGGAACGC-3⬘; PHD2F, 5⬘-GATGAGGAAAAG ...
... pCR2.1-ACF1-flag using the Site-directed Mutagenesis Kit (Stratagene). The following pairs of oligonucleotides were used to delete the PHD1 or PHD2, respectively: PHD1F, 5⬘-ACCAATAAGTCATTAGTCGACGTAAAGAGTCTGGGTCTCAGC-3⬘; PHD1R, 5⬘-ACCCAGACTCTTTACGTCGACTAATGACTTATTGGTGGAACGC-3⬘; PHD2F, 5⬘-GATGAGGAAAAG ...
PDF
... Fig.2.The minimal inferred complexity of Hox gene clusters in the lineage leading to the insects. Panels on the right summarise the diversity of Hox genes described from insects, Crustacea, annelids (Class Hirudinea, leeches) and chordates(Amphioxus, and several vertebrates; a single 'complete' chor ...
... Fig.2.The minimal inferred complexity of Hox gene clusters in the lineage leading to the insects. Panels on the right summarise the diversity of Hox genes described from insects, Crustacea, annelids (Class Hirudinea, leeches) and chordates(Amphioxus, and several vertebrates; a single 'complete' chor ...
The Schistosoma gene discovery program: state of the art
... and even a transcript of unknown function have been used for full length sequencing and detailed characterisation of the gene of interest [21±27] or as probes for chromosome mapping [28]. It is very dicult to keep Schistosoma in the laboratory. The complex life cycle can only be maintained by passa ...
... and even a transcript of unknown function have been used for full length sequencing and detailed characterisation of the gene of interest [21±27] or as probes for chromosome mapping [28]. It is very dicult to keep Schistosoma in the laboratory. The complex life cycle can only be maintained by passa ...
THE STRUCTURE OF CHROMATIN
... is the binding of these proteins that causes the changes in chromatin. Gene silencing and cell “memory” The cells of the very early embryo are said to be totipotent; that is they can differentiate into any of the cells required by the adult organism. After a certain number of divisions (mitoses), ho ...
... is the binding of these proteins that causes the changes in chromatin. Gene silencing and cell “memory” The cells of the very early embryo are said to be totipotent; that is they can differentiate into any of the cells required by the adult organism. After a certain number of divisions (mitoses), ho ...
Expression of the Mitochondrial ATPase6 Gene and Tfam in Down
... Furthermore, we have shown that decreased Tfam expression may cause nondisjunction because the required energy for spindle assembly has not been supplied. Therefore, our research suggests that mitochondrial dysfunction due to various extrinsic or intrinsic influences can induce aneuploidies such as ...
... Furthermore, we have shown that decreased Tfam expression may cause nondisjunction because the required energy for spindle assembly has not been supplied. Therefore, our research suggests that mitochondrial dysfunction due to various extrinsic or intrinsic influences can induce aneuploidies such as ...
journals - the biopsychology research group
... removed during early germ cell development, re-established later in germ cell development or after fertilization, and maintained during embryonic development. ‘‘Imprinting’’ of the gene effectively tells the molecular machinery within the cell to express only one allele in the cell and its progeny. ...
... removed during early germ cell development, re-established later in germ cell development or after fertilization, and maintained during embryonic development. ‘‘Imprinting’’ of the gene effectively tells the molecular machinery within the cell to express only one allele in the cell and its progeny. ...
Document
... (MLG) 13_A2, pairs of isolates representing other dominant MLGs from the 2006 Great Britain (GB) population, additional isolates from other parts of Europe (The Netherlands, Sweden and Poland) and two reference isolates from Scotland in the 1990s. The isolates from the Netherlands were MLG 13_A2 whe ...
... (MLG) 13_A2, pairs of isolates representing other dominant MLGs from the 2006 Great Britain (GB) population, additional isolates from other parts of Europe (The Netherlands, Sweden and Poland) and two reference isolates from Scotland in the 1990s. The isolates from the Netherlands were MLG 13_A2 whe ...
5` Flanking Sequences of the Rat Tyrosine Hydroxylase Gene Target
... disparate cell groups might be expected to rely on multiple regulatory elements, some that may be needed in all TH tissues and others that may mediate expression in a particular cell group. As a first step in defining elements that direct cell-specific expression of TH, we sought to identify those D ...
... disparate cell groups might be expected to rely on multiple regulatory elements, some that may be needed in all TH tissues and others that may mediate expression in a particular cell group. As a first step in defining elements that direct cell-specific expression of TH, we sought to identify those D ...
Chromosome Structure Variations
... present in the haploid genome. • Some duplications are “dispersed”, found in very different locations from each other. • Other duplications are “tandem”, found next to each other. • Tandem duplications play a major role in evolution, because it is easy to generate extra copies of the duplicated gene ...
... present in the haploid genome. • Some duplications are “dispersed”, found in very different locations from each other. • Other duplications are “tandem”, found next to each other. • Tandem duplications play a major role in evolution, because it is easy to generate extra copies of the duplicated gene ...
Mary Ann Osley*, Alastair Fleming, and Cheng
... linkage between ubiquitin and the target protein or between individual ubiquitin molecules in the case of polyubiquitylation. The large family of Ubps suggests that, like E3s, Ubps have significant specificity with respect their targets. Moreover, multiple Ubps may act on a single target. For exampl ...
... linkage between ubiquitin and the target protein or between individual ubiquitin molecules in the case of polyubiquitylation. The large family of Ubps suggests that, like E3s, Ubps have significant specificity with respect their targets. Moreover, multiple Ubps may act on a single target. For exampl ...
