Recent Statistical Approaches
... A microarray is a new technology which allows the measurement of the expression levels of thousands of genes simultaneously. (1) sequencing of the genome (human, mouse, and others) (2) improvement in technology to generate high-density arrays on chips (glass slides or nylon membrane). ...
... A microarray is a new technology which allows the measurement of the expression levels of thousands of genes simultaneously. (1) sequencing of the genome (human, mouse, and others) (2) improvement in technology to generate high-density arrays on chips (glass slides or nylon membrane). ...
view pdf - University of Arizona
... gametophyte has presented a significant challenge to the plant biology community. The angiosperm female gametophyte is fairly inaccessible because it is a highly reduced structure relative to the sporophyte and is embedded within multiple layers of the sporophytic tissue of the ovule. Moreover, alth ...
... gametophyte has presented a significant challenge to the plant biology community. The angiosperm female gametophyte is fairly inaccessible because it is a highly reduced structure relative to the sporophyte and is embedded within multiple layers of the sporophytic tissue of the ovule. Moreover, alth ...
The relation of genetics to physiology and medicine
... order in the chromosomes is deducible, both from genetic evidence and from cytological observations. Whether the relative position is no more than a historical accident, or whether it is due to some relation between each gene and its neighbors, can not be definitely stated. But the evidence from the ...
... order in the chromosomes is deducible, both from genetic evidence and from cytological observations. Whether the relative position is no more than a historical accident, or whether it is due to some relation between each gene and its neighbors, can not be definitely stated. But the evidence from the ...
Biol115_2014_Lecture 10_Prokaryotic Gene Regulation
... • The operon can be switched off by a protein repressor! • The repressor prevents gene transcription by binding to the operator and blocking RNA polymerase" • The repressor is the product of a separate regulatory gene! • The repressor can be in an active or inactive form, depending on the presen ...
... • The operon can be switched off by a protein repressor! • The repressor prevents gene transcription by binding to the operator and blocking RNA polymerase" • The repressor is the product of a separate regulatory gene! • The repressor can be in an active or inactive form, depending on the presen ...
20.15 Enhancers contain the same elements that are
... An authentic GAL4 protein can activate a target gene only if it has a UAS. The LexA repressor by itself of course lacks the ability to activate either sort of target. The LexA-GAL4 hybrid can no longer activate a gene with a UAS, but it can now activate a gene that has a LexA operator! This result f ...
... An authentic GAL4 protein can activate a target gene only if it has a UAS. The LexA repressor by itself of course lacks the ability to activate either sort of target. The LexA-GAL4 hybrid can no longer activate a gene with a UAS, but it can now activate a gene that has a LexA operator! This result f ...
Gene Section DHX9 (DEAH (Asp Glu Ala
... a highly structured 5'UTR. DHX9 might be necessary for maintaining genomic stability as it plays a role in promoting the DNA processing function of WRN. Overexpression of a truncated DHX9 peptide prevents normal BRCA1 function, such as BRCA1 association with nuclear foci following DNA damage. DHX9 a ...
... a highly structured 5'UTR. DHX9 might be necessary for maintaining genomic stability as it plays a role in promoting the DNA processing function of WRN. Overexpression of a truncated DHX9 peptide prevents normal BRCA1 function, such as BRCA1 association with nuclear foci following DNA damage. DHX9 a ...
The relation of genetics to physiology and medicine
... order in the chromosomes is deducible, both from genetic evidence and from cytological observations. Whether the relative position is no more than a historical accident, or whether it is due to some relation between each gene and its neighbors, can not be definitely stated. But the evidence from the ...
... order in the chromosomes is deducible, both from genetic evidence and from cytological observations. Whether the relative position is no more than a historical accident, or whether it is due to some relation between each gene and its neighbors, can not be definitely stated. But the evidence from the ...
Genetic Regulatory Network Identification Using
... of our earlier work in [9], which proposed a different approach from those in the above references. Although we still use the dynamical system formulation, there is no assumption made about the type of the functions used in the regulation (e.g. linear, polynomial, Hill functions, etc.). The only imp ...
... of our earlier work in [9], which proposed a different approach from those in the above references. Although we still use the dynamical system formulation, there is no assumption made about the type of the functions used in the regulation (e.g. linear, polynomial, Hill functions, etc.). The only imp ...
- bioRxiv
... lowest we observed. This suggests that expression variation is reduced by X chromosome dosage compensation. Finally, a comparison with variations in control spike-in measures (Fig 1B) confirms that the observed variability is biological rather than technical. We confirm this observation below in ana ...
... lowest we observed. This suggests that expression variation is reduced by X chromosome dosage compensation. Finally, a comparison with variations in control spike-in measures (Fig 1B) confirms that the observed variability is biological rather than technical. We confirm this observation below in ana ...
PowerPoint 프레젠테이션
... - dsRNA is the interfering agent (stability) - it is highly specific - it is remarkably potent (only a few dsRNA molecules per cell are required for effective interference) - the interfering activity can cause interference in cells and tissues far removed from the site of introduction RNAi for analy ...
... - dsRNA is the interfering agent (stability) - it is highly specific - it is remarkably potent (only a few dsRNA molecules per cell are required for effective interference) - the interfering activity can cause interference in cells and tissues far removed from the site of introduction RNAi for analy ...
Chapter 25 RNA Metabolism
... Transcription is the first step in the complicated and energy-expensive pathway leading to protein synthesis, an ideal target for regulating gene expression. The RNA polymerase binds to each promoter in very different efficiency. Protein factors binding to DNA sequences close or distant to the p ...
... Transcription is the first step in the complicated and energy-expensive pathway leading to protein synthesis, an ideal target for regulating gene expression. The RNA polymerase binds to each promoter in very different efficiency. Protein factors binding to DNA sequences close or distant to the p ...
Arabidopsis VARIEGATED 3 encodes a chloroplast
... including failure in palisade cell expansion. As these genes encode chloroplast proteins, mutations in them may affect cell development because of incomplete chloroplast biogenesis. While most such mutations lead to decreased Lhcb and RbcS mRNA levels, pac1 accumulates normal levels of Lhcb mRNA. Th ...
... including failure in palisade cell expansion. As these genes encode chloroplast proteins, mutations in them may affect cell development because of incomplete chloroplast biogenesis. While most such mutations lead to decreased Lhcb and RbcS mRNA levels, pac1 accumulates normal levels of Lhcb mRNA. Th ...
PDF
... whose members have been implicated in RNAi and related phenomena in several organisms. In addition to roles in RNAi-like mechanisms, Argonaute proteins influence development, and at least a subset are involved in stem cell fate determination. Argonaute proteins are ∼100-kD highly basic proteins that ...
... whose members have been implicated in RNAi and related phenomena in several organisms. In addition to roles in RNAi-like mechanisms, Argonaute proteins influence development, and at least a subset are involved in stem cell fate determination. Argonaute proteins are ∼100-kD highly basic proteins that ...
Glycosylphosphatidyl inositol-anchored protein (GPI
... expressed genes. We validated the differential expression of several of the genes identified through Biochip analysis, by means of quantitative RT-PCR of RNA from 48 thymoma tumors. We found that GPI-80 was significantly higher in invasive thymoma (stage IV thymoma) than in stage I thymoma. It has p ...
... expressed genes. We validated the differential expression of several of the genes identified through Biochip analysis, by means of quantitative RT-PCR of RNA from 48 thymoma tumors. We found that GPI-80 was significantly higher in invasive thymoma (stage IV thymoma) than in stage I thymoma. It has p ...
lecture notes
... system of the adult fly. In principle, both high and low levels of the Dorsal gradient can activate Sog expression in both the mesoderm and neurogenic ectoderm. However, the Sog enhancer contains binding sites for both Dorsal and Snail, which functions as a transcriptional repressor to exclude Sog e ...
... system of the adult fly. In principle, both high and low levels of the Dorsal gradient can activate Sog expression in both the mesoderm and neurogenic ectoderm. However, the Sog enhancer contains binding sites for both Dorsal and Snail, which functions as a transcriptional repressor to exclude Sog e ...
Functional analyses of genetic pathways controlling
... The roles of paleoAP3 genes in non-core eudicot angiosperms are somewhat unclear. A variety of expression analyses have been carried out that, in general, support the idea that paleoAP3 genes have a conserved role in stamen identity specification, but their role in petal specification remains ambigu ...
... The roles of paleoAP3 genes in non-core eudicot angiosperms are somewhat unclear. A variety of expression analyses have been carried out that, in general, support the idea that paleoAP3 genes have a conserved role in stamen identity specification, but their role in petal specification remains ambigu ...
Genome-Wide Gene Expression Effects of Sex Chromosome
... X-X and X-Y chromosomes to generate three contrasts (Figure 1): males that inherit a maternal X chromosome and a paternal Y chromosome (XMYP) vs. males that inherit a paternal X and a maternal Y (XPYM); males that inherit a maternal compound X-Y chromosome and a paternal free Y (XYMYP) chromosome vs ...
... X-X and X-Y chromosomes to generate three contrasts (Figure 1): males that inherit a maternal X chromosome and a paternal Y chromosome (XMYP) vs. males that inherit a paternal X and a maternal Y (XPYM); males that inherit a maternal compound X-Y chromosome and a paternal free Y (XYMYP) chromosome vs ...
Identification of genes expressed in the angiosperm female
... gametophyte has presented a significant challenge to the plant biology community. The angiosperm female gametophyte is fairly inaccessible because it is a highly reduced structure relative to the sporophyte and is embedded within multiple layers of the sporophytic tissue of the ovule. Moreover, alth ...
... gametophyte has presented a significant challenge to the plant biology community. The angiosperm female gametophyte is fairly inaccessible because it is a highly reduced structure relative to the sporophyte and is embedded within multiple layers of the sporophytic tissue of the ovule. Moreover, alth ...
Gill: Gene Regulation II
... repression (that lowers/ablates tx output). • Transcription factors can bind key genomic sites, preventing/repelling the binding of – The RNA polymerase machinery – Activating transcription factors (including via competitive binding) • Some transcription factors have stereotypical roles as activator ...
... repression (that lowers/ablates tx output). • Transcription factors can bind key genomic sites, preventing/repelling the binding of – The RNA polymerase machinery – Activating transcription factors (including via competitive binding) • Some transcription factors have stereotypical roles as activator ...
Li, H., and Baker, B. S.
... necessary for male sexual behavior (Hall, 1994; Ito et al., 1996; Ryner et al., 1996; Taylor et al., 1994) and the development of a male-specific abdominal muscle, the Muscle of Lawrence (MOL) (Gailey et al., 1991; Ito et al., 1996; Lawrence and Johnston, 1986; Ryner et al., 1996). The female-specif ...
... necessary for male sexual behavior (Hall, 1994; Ito et al., 1996; Ryner et al., 1996; Taylor et al., 1994) and the development of a male-specific abdominal muscle, the Muscle of Lawrence (MOL) (Gailey et al., 1991; Ito et al., 1996; Lawrence and Johnston, 1986; Ryner et al., 1996). The female-specif ...
GAL4 enhancer trap strains with reporter gene expression during
... probably specified at the embryonic stage but become mitotically quiescent in the early larva. These cells re-enter the proliferative phase at 12–36 h of larval period and generate clusters of immature postmitotic neurons by late third instar. They do not have any obvious function in larva and are r ...
... probably specified at the embryonic stage but become mitotically quiescent in the early larva. These cells re-enter the proliferative phase at 12–36 h of larval period and generate clusters of immature postmitotic neurons by late third instar. They do not have any obvious function in larva and are r ...