Patterns of gene action in plant development revealed by enhancer
... McClintock's investigations on alterations in the patterns of "gene action" in maize kernels led to the discovery of transposable elements (McClintock 1950). Subsequently, transposable elements have been found in almost all organisms examined and are believed to constitute a major agent for the gene ...
... McClintock's investigations on alterations in the patterns of "gene action" in maize kernels led to the discovery of transposable elements (McClintock 1950). Subsequently, transposable elements have been found in almost all organisms examined and are believed to constitute a major agent for the gene ...
The role of Dby mRNA in early development of male mouse zygotes
... and shedding cytoplasm during the later stage of spermatogenesis. However, recent evidence suggests that a complex specific mRNA population is retained in freshly ejaculated spermatozoa of several species [1–4]. In addition, some spermatozoa mRNAs are transferred into the oocyte during fertilization ...
... and shedding cytoplasm during the later stage of spermatogenesis. However, recent evidence suggests that a complex specific mRNA population is retained in freshly ejaculated spermatozoa of several species [1–4]. In addition, some spermatozoa mRNAs are transferred into the oocyte during fertilization ...
presentation_ewggd_2..
... There is UPR in GD patients There is UPR in one animal models (out of few we have tested) There is UPR in GD carriers including the 84GG carriers There is upregulation of the GBA gene in patients in response to UPR, through CHOP binding Even without ERAD there is UPR (ER stress) that may lead to dea ...
... There is UPR in GD patients There is UPR in one animal models (out of few we have tested) There is UPR in GD carriers including the 84GG carriers There is upregulation of the GBA gene in patients in response to UPR, through CHOP binding Even without ERAD there is UPR (ER stress) that may lead to dea ...
Supplementary Information (doc 1628K)
... primeview assay for target synthesis and labeling. Samples were hybridized to the Genechip primeview human gene expression array and those demonstrating a cutoff greater or less than 1.5-fold difference from the parental cell line used for further analysis. The quality of the total RNA was confirmed ...
... primeview assay for target synthesis and labeling. Samples were hybridized to the Genechip primeview human gene expression array and those demonstrating a cutoff greater or less than 1.5-fold difference from the parental cell line used for further analysis. The quality of the total RNA was confirmed ...
Microarray Data Analysis
... value for a particular sample for a particular gene, followed by preprocessing or data normalization and transformation. Basically this step eliminates house keeping or control genes, genes with less than two fold change in expression level to reduce the noise and identify genes with specific change ...
... value for a particular sample for a particular gene, followed by preprocessing or data normalization and transformation. Basically this step eliminates house keeping or control genes, genes with less than two fold change in expression level to reduce the noise and identify genes with specific change ...
Impact of nucleosome dynamics and histone modifications
... the SWR1/SRCAP ATPase complex (March-Diaz and Reyes, 2009), that is associated with transcriptionally active genes. SWI/SNF chromatin remodeling complexes, which contribute to the ATP hydrolysis-dependent nucleosome sliding, regulate transcriptional programmes in response to exogenous and endogenous ...
... the SWR1/SRCAP ATPase complex (March-Diaz and Reyes, 2009), that is associated with transcriptionally active genes. SWI/SNF chromatin remodeling complexes, which contribute to the ATP hydrolysis-dependent nucleosome sliding, regulate transcriptional programmes in response to exogenous and endogenous ...
Genomic Survey and Gene Expression Analysis
... genes. The OsbZIP genes were given a number designation from 1 to 89 to provide a unique identifier for each bZIP transcription factor gene as proposed for bZIP transcription factors in Arabidopsis (Jakoby et al., 2002). The nomenclature was based on their position on rice chromosomes 1 to 12 and fr ...
... genes. The OsbZIP genes were given a number designation from 1 to 89 to provide a unique identifier for each bZIP transcription factor gene as proposed for bZIP transcription factors in Arabidopsis (Jakoby et al., 2002). The nomenclature was based on their position on rice chromosomes 1 to 12 and fr ...
Virus on virus infects bacterium
... other. For example, not all strains of V. cholerae that express TCP can form transferable bacteriophage particles. Perhaps most of the TcpA is incorporated into a colonization pilus, and the remainder is used to coat the DNA in infectious phage particles (but only in those strains that can produce t ...
... other. For example, not all strains of V. cholerae that express TCP can form transferable bacteriophage particles. Perhaps most of the TcpA is incorporated into a colonization pilus, and the remainder is used to coat the DNA in infectious phage particles (but only in those strains that can produce t ...
Induction of the white egg3 mutant phenotype by injection of the
... of GFP dsRNA did not reduce endogenous Bmwh3 mRNA. Sequence-specific silencing was also shown for GFP expression by interfering with the transient expression of GFP from a plasmid without affecting the colour of the eggs and larvae. This is the first report in which it is shown that RNAi acts in the ...
... of GFP dsRNA did not reduce endogenous Bmwh3 mRNA. Sequence-specific silencing was also shown for GFP expression by interfering with the transient expression of GFP from a plasmid without affecting the colour of the eggs and larvae. This is the first report in which it is shown that RNAi acts in the ...
Evolutionary interactions between sex chromosomes and autosomes
... are located on the X appeared to avoid inserting its retrogenes onto the X chromosome. Among 44 X-derived retrogenes, only one was re-inserted onto the X whereas the other 43 moved to autosomes 2 and 3. Thus, these within-chromosomal data further supported the interchromosomal analysis: the X chromo ...
... are located on the X appeared to avoid inserting its retrogenes onto the X chromosome. Among 44 X-derived retrogenes, only one was re-inserted onto the X whereas the other 43 moved to autosomes 2 and 3. Thus, these within-chromosomal data further supported the interchromosomal analysis: the X chromo ...
Chromatin regulation during C. elegans germline development
... modifications, Kelly et al. [8] report that the C. elegans X chromosome is subject to selective repression during much of germline development. It is well accepted that chromatin is organized by linker histones and other binding proteins, which in turn respond to differential modification of core h ...
... modifications, Kelly et al. [8] report that the C. elegans X chromosome is subject to selective repression during much of germline development. It is well accepted that chromatin is organized by linker histones and other binding proteins, which in turn respond to differential modification of core h ...
Creating conditional dual fluorescence labelled transgenic animals
... In addition to messenger RNA that encodes proteins, non-coding RNAs, including microRNA (miRNA) and long non-coding RNA (lncRNA) have been shown to be involved in gene regulation at post-transcriptional and translational levels. For example, microRNAs, about 22 nucleotide long, are among the largest ...
... In addition to messenger RNA that encodes proteins, non-coding RNAs, including microRNA (miRNA) and long non-coding RNA (lncRNA) have been shown to be involved in gene regulation at post-transcriptional and translational levels. For example, microRNAs, about 22 nucleotide long, are among the largest ...
Human, yeast and hybrid 3-phosphoglycerate kinase gene
... expression unit b, protein levels of all hPGK containing expression units are significantly decreased. Differences in migration of the various PGKs are due to differences in amino acid compositions (15). The above results are summarized in Table 1. mRNA Production by the Different Expression Units F ...
... expression unit b, protein levels of all hPGK containing expression units are significantly decreased. Differences in migration of the various PGKs are due to differences in amino acid compositions (15). The above results are summarized in Table 1. mRNA Production by the Different Expression Units F ...
AllBio_DJK
... • Most significant gene from eQTL study • Mitochondrial gene • Function of this particular gene not clear. • “Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the ...
... • Most significant gene from eQTL study • Mitochondrial gene • Function of this particular gene not clear. • “Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the ...
Ch. 15 The Chromosomal Basis of Inheritance
... *due to random orientation of homologous chromosomes on metaphase 1 plate of meiosis = independent assortment of alleles ...
... *due to random orientation of homologous chromosomes on metaphase 1 plate of meiosis = independent assortment of alleles ...
Gene targeting by hybridization-hydrolysis process
... A new technology used to specifically target any transcript from a complex population of single-strand cDNA molecules was applied to dramatically decrease the abundance of selected genes in cDNA libraries. This innovative procedure offers new alternatives to previous efforts focused on normalizing t ...
... A new technology used to specifically target any transcript from a complex population of single-strand cDNA molecules was applied to dramatically decrease the abundance of selected genes in cDNA libraries. This innovative procedure offers new alternatives to previous efforts focused on normalizing t ...
GATA factor function in heart development
... y w67c23 served as our wild-type stock. The Gal4 strain used to direct gene expression in the mesoderm and mesectoderm was twi-Gal4 (Baylies and Bate, 1996). The UAS lines included UAS-pnr (Haenlin et al., 1997), UAS-tin (Yin and Frasch, 1998) and UAS-GATA4 generated in this study. The latter was ob ...
... y w67c23 served as our wild-type stock. The Gal4 strain used to direct gene expression in the mesoderm and mesectoderm was twi-Gal4 (Baylies and Bate, 1996). The UAS lines included UAS-pnr (Haenlin et al., 1997), UAS-tin (Yin and Frasch, 1998) and UAS-GATA4 generated in this study. The latter was ob ...
Methods of screening for bioactive agents using cells transformed
... draWbacks. First, the presence of viral promoters at the 5‘ long terminal repeats (LTR) may result in mobiliZation or rescue of an integrated provirus by endogenous retroviruses or upon infection With retroviral vectors that express viral ...
... draWbacks. First, the presence of viral promoters at the 5‘ long terminal repeats (LTR) may result in mobiliZation or rescue of an integrated provirus by endogenous retroviruses or upon infection With retroviral vectors that express viral ...
Regulation and Flexibility of Genomic Imprinting
... Imprinted genes encode a wide range of molecular functions, ranging from the regulation of pigmentation, protein storage, transcriptional regulation, chromatin modification, and cytoskeletal function to mRNA regulation (Table 1). For instance, five recently described potentially imprinted genes, for ...
... Imprinted genes encode a wide range of molecular functions, ranging from the regulation of pigmentation, protein storage, transcriptional regulation, chromatin modification, and cytoskeletal function to mRNA regulation (Table 1). For instance, five recently described potentially imprinted genes, for ...