Coffee, B, Zhang, F, Warren, ST and Reines, D: Acetylated histones are associated with the FMR1 gene in normal but not fragile X syndrome cells. Nature Genetics 22:98-101 (1999).
... patients appears to be associated with unacetylated histones. RT-PCR analysis of total RNA from five normal and five fragile X cell lines showed that FMR1 was transcriptionally active in the former and transcriptionally silent in the latter (Fig. 1b). These results show a direct correlation between ...
... patients appears to be associated with unacetylated histones. RT-PCR analysis of total RNA from five normal and five fragile X cell lines showed that FMR1 was transcriptionally active in the former and transcriptionally silent in the latter (Fig. 1b). These results show a direct correlation between ...
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting Open Access
... imprinted [11,17,26-33]. These are IGF2, IGF2R, PEG1/ MEST, PEG10, INS and H19, and are from 4 independent domains. We have previously reported that there is no evidence of genomic imprinting of CDKN1C (also known as p57KIP2) in a marsupial, the tammar wallaby (Macropus eugenii) [28,34]. CDKN1C is l ...
... imprinted [11,17,26-33]. These are IGF2, IGF2R, PEG1/ MEST, PEG10, INS and H19, and are from 4 independent domains. We have previously reported that there is no evidence of genomic imprinting of CDKN1C (also known as p57KIP2) in a marsupial, the tammar wallaby (Macropus eugenii) [28,34]. CDKN1C is l ...
Alu Human Polymorphism
... – -/- has one smaller band around 400bp, +/+ has one larger band around 700bp; +/- has two bands one at 400 and one at 700 – There is a picture of a control gel on: http://www.geneticorigins.org/pv92/aluframeset.htm under the ...
... – -/- has one smaller band around 400bp, +/+ has one larger band around 700bp; +/- has two bands one at 400 and one at 700 – There is a picture of a control gel on: http://www.geneticorigins.org/pv92/aluframeset.htm under the ...
The Chloroplast trnT–trnF Region in the Seed Plant
... Plant DNeasy minikits. Concentration and quality of extracted DNAs were checked by 1% agarose gel electrophoresis with a (kHindIII/EcoRI size marker. The chloroplast tRNALeu(UAA) intron and adjacent IGSs were amplified using primers designed by Taberlet et al. (1991) (Fig. 1 shows their placement). T ...
... Plant DNeasy minikits. Concentration and quality of extracted DNAs were checked by 1% agarose gel electrophoresis with a (kHindIII/EcoRI size marker. The chloroplast tRNALeu(UAA) intron and adjacent IGSs were amplified using primers designed by Taberlet et al. (1991) (Fig. 1 shows their placement). T ...
Major influence of repetitive elements on disease
... syndrome (OMIM #194050) [6]. Genes within this region are dosage-sensitive and the recurrently deleted region encompasses a total of 28 genes. This locus is characterized by highly homologous flanking LCRs that contribute to NAHR events [6]. Antonell and colleagues [36] reported the presence of Alu ...
... syndrome (OMIM #194050) [6]. Genes within this region are dosage-sensitive and the recurrently deleted region encompasses a total of 28 genes. This locus is characterized by highly homologous flanking LCRs that contribute to NAHR events [6]. Antonell and colleagues [36] reported the presence of Alu ...
This article appeared in a journal published by Elsevier. The
... NLS(s) but still within the arginine-rich region (ARR) located in the N-terminal half of the 2b protein [9]. Based on RNA sequence data, CMV strains can be classified into three subgroups, IA, IB and II [20]. It has been found that subgroup I strains are, in general, more virulent than subgroup II st ...
... NLS(s) but still within the arginine-rich region (ARR) located in the N-terminal half of the 2b protein [9]. Based on RNA sequence data, CMV strains can be classified into three subgroups, IA, IB and II [20]. It has been found that subgroup I strains are, in general, more virulent than subgroup II st ...
Effects of cis and trans Genetic Ancestry on Gene Expression in
... number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that individuals from this population inherit variable proportion ...
... number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that individuals from this population inherit variable proportion ...
Molecular cloning and functional characterisation of a glucose
... PDR3, which are present in HXT9 and HXT11 of S. cerevisiae, were absent in CaHGT1 promoter. 3.3. CaHGT1 could complement the glucose transport defect when expressed in S. cerevisiae In order to check the functionality of the cloned putative glucose transporter, the glucose uptake-de¢cient strain RE7 ...
... PDR3, which are present in HXT9 and HXT11 of S. cerevisiae, were absent in CaHGT1 promoter. 3.3. CaHGT1 could complement the glucose transport defect when expressed in S. cerevisiae In order to check the functionality of the cloned putative glucose transporter, the glucose uptake-de¢cient strain RE7 ...
Gene overexpression reveals alternative
... increase in GCN4 mRNA translation, coupled with an extensive protein synthesis shut down. However, both phenomena are independent of Gcn2 function (Tzamarias et al., 1989). In addition, the assimilation of GCN4 mRNA translational derepression in vitro, does not require the Gcn2 kinase (Krupitza and ...
... increase in GCN4 mRNA translation, coupled with an extensive protein synthesis shut down. However, both phenomena are independent of Gcn2 function (Tzamarias et al., 1989). In addition, the assimilation of GCN4 mRNA translational derepression in vitro, does not require the Gcn2 kinase (Krupitza and ...
The chromatin remodelling factor Brg1 interacts with catenin to
... protein CBP/p300 (Hecht et al., 2000; Takemaru and Moon, 2000). CBP/p300 is considered to promote gene activation by virtue of its HAT activity, following its recruitment to target gene promoters via interaction with the activation domains of transcription factors (Cheung et al., 2000). Additionally ...
... protein CBP/p300 (Hecht et al., 2000; Takemaru and Moon, 2000). CBP/p300 is considered to promote gene activation by virtue of its HAT activity, following its recruitment to target gene promoters via interaction with the activation domains of transcription factors (Cheung et al., 2000). Additionally ...
Information Encoding in Biological Molecules: DNA and protein
... • Among the test samples, 7 have not recurred within 5 years and 12 did. • The data were collected on two color Agilent oligo arrays containing about 24K genes. ...
... • Among the test samples, 7 have not recurred within 5 years and 12 did. • The data were collected on two color Agilent oligo arrays containing about 24K genes. ...
hindlimb - bthsresearch
... engineered to express a gene of interest • The embryo can then be injected with the virus at an early stage • As virus spreads through the developing tissue, gene expression is turned on • In this way we can express genes ectopically in chick tissue – Like a gain of function mutation in a mouse, but ...
... engineered to express a gene of interest • The embryo can then be injected with the virus at an early stage • As virus spreads through the developing tissue, gene expression is turned on • In this way we can express genes ectopically in chick tissue – Like a gain of function mutation in a mouse, but ...
Analysis of non‐polar deletion mutations in the genes of the spo0K
... dipeptides into the cell, but this transport is dependent on spo0K (F. Slack and A.L. Sonenshein, personal communication). Another example more pertinent to these results is the ability of UgpC, the single ATP-binding protein of the sn-glycerol-3-phosphate ABC transporter Ugp, to substitute for MalK ...
... dipeptides into the cell, but this transport is dependent on spo0K (F. Slack and A.L. Sonenshein, personal communication). Another example more pertinent to these results is the ability of UgpC, the single ATP-binding protein of the sn-glycerol-3-phosphate ABC transporter Ugp, to substitute for MalK ...
ChromatinDB: a database of genome-wide
... this manner in yeast alone (Millar and Grunstein, 2006). These data provide a genome-wide map of genomic regions that are enriched or depleted of each type of histone modification. Also available are data sets measuring the relative association of the histone proteins themselves (histone H2A, H2A.Z, ...
... this manner in yeast alone (Millar and Grunstein, 2006). These data provide a genome-wide map of genomic regions that are enriched or depleted of each type of histone modification. Also available are data sets measuring the relative association of the histone proteins themselves (histone H2A, H2A.Z, ...
2.5.6 Genetic Inheritance 2.5.7 Causes of Variation 2.5.8 Evolution
... Q. Name the sex chromosomes that are present in a human female cell. Allele only expressed in the homozygous condition ...
... Q. Name the sex chromosomes that are present in a human female cell. Allele only expressed in the homozygous condition ...
Seven
... To compare the results obtained by our algorithm with some well-established genefinding program, we introduced new simple rules for deciding if a given ORF is coding or non-coding. For every ORF, we calculate 64-dimensional vector of it’s codon frequencies and find the closest centroid in the codon ...
... To compare the results obtained by our algorithm with some well-established genefinding program, we introduced new simple rules for deciding if a given ORF is coding or non-coding. For every ORF, we calculate 64-dimensional vector of it’s codon frequencies and find the closest centroid in the codon ...
Knockdown of Parhyale Ultrabithorax - IMBB
... of the same individual as well. Appendages of the posterior head segments are part of the jaw apparatus that crushes food and moves it to the mouth during feeding. The more posterior appendages of the crustacean trunk serve numerous roles including mating, defense, and locomotion. The pattern of the ...
... of the same individual as well. Appendages of the posterior head segments are part of the jaw apparatus that crushes food and moves it to the mouth during feeding. The more posterior appendages of the crustacean trunk serve numerous roles including mating, defense, and locomotion. The pattern of the ...
1471-2164-10-531-S3
... Figure S3. Tag Count Distribution of PGK1. PGK1 has 11 known exons. Among randomly selected 0.5, 1.0, 1.5, 2.0, 3.0, 5.0, 10. 15, and 20 million tags from UHRR sample, we have consistently observed 5 tags from the 3’ most exon, and 1 tag from the 5th exon from the 3’ end. As shown in the figure abov ...
... Figure S3. Tag Count Distribution of PGK1. PGK1 has 11 known exons. Among randomly selected 0.5, 1.0, 1.5, 2.0, 3.0, 5.0, 10. 15, and 20 million tags from UHRR sample, we have consistently observed 5 tags from the 3’ most exon, and 1 tag from the 5th exon from the 3’ end. As shown in the figure abov ...