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Hyper-eccentric structural genes in the mitochondrial genome of the
Hyper-eccentric structural genes in the mitochondrial genome of the

... pattern is generally conserved among the diplonemid species studied to date (Marande and Burger 2007; Kiethega et al. 2011); the number of modules and fragmented positions found in cox1 are generally the same among four diplonemid species sequenced to date. Each module is independently transcribed, ...
First report of a tetracycline-inducible gene
First report of a tetracycline-inducible gene

... Mollicutes are known as having lost most of their regulatory systems during their reductive evolution. Very few regulators have been identified and studies on transcription regulation are still limited (Halbedel et al., 2007; Musatovova et al., 2006; Weiner et al., 2003). In S. citri, the existence ...
PDF
PDF

... with the JIL-1 mAb 5C9 and with antibody to the elongating form of RNA polymerase II (Pol IIoser2), which is phosphorylated at serine 2 in the C-terminal domain and which serves as a marker for active transcription (Weeks et al., 1993; Boehm et al., 2003; Ivaldi et al., 2007). In non-heat shock prep ...
Genomic Consequences of Background Effects on scalloped Mutant
Genomic Consequences of Background Effects on scalloped Mutant

... mutations can establish whether a gene is necessary for a particular developmental event or regulation of other genes. Developmental genetic analyses often use allelic series ranging from weak hypomorphic to null (amorphic) mutations to study specific aspects of the gene structure/function relations ...
Maimbo, M., Ohnishi, K., Hikichi, Y., Yoshioka, H. and Kiba, A.
Maimbo, M., Ohnishi, K., Hikichi, Y., Yoshioka, H. and Kiba, A.

Modifiers of epigenetic reprogramming show paternal effects in the mouse
Modifiers of epigenetic reprogramming show paternal effects in the mouse

... if heterozygosity results in a detectable phenotype. Because the mouse screen is dominant, it will specifically identify such genes. The experiments described below investigate the effects of mutations in such genes in the male parent on a maternally inherited reporter allele in the offspring (that ...
Mapping the histone code at hMLH1. - JScholarship
Mapping the histone code at hMLH1. - JScholarship

... 2002). More recently, it was shown that induction of a heat shock gene displaces both H3.3 and H3, followed by selective deposition of H3.3 (Wirbelauer et al., 2005). When comparing histone tail modification profiles of H3 and H3.3, although none of the modifications examined were exclusive to eithe ...
Epigenetic memory in mammals
Epigenetic memory in mammals

... indicating that most protamines were removed within 30 min following fertilization (van der Heijden et al., 2005). The histones, which associate with the paternal chromatin, are more acetylated than those already present in the maternal chromatin (Lange and Schneider, 2010). It is possible this imba ...
Axial homeosis and appendicular skeleton defects in mice with a
Axial homeosis and appendicular skeleton defects in mice with a

... The vertebrate limb initially appears as a bud of mesenchyme that originates from the lateral plate mesoderm. The outgrowth of the limb bud is controlled by the apical ectodermal ridge (AER), which maintains the underlying mesoderm (the progress zone) in a highly proliferative state. As the limb gro ...
Animal Models of human DCG`s
Animal Models of human DCG`s

... Lecture Goal – Exam Question You are reading a Times article with a friend and you come across the following statement: “The study hypothesized that some of these susceptibility factors may be allelic variants of genes that govern embryonic serotonin neuron development and that these alleles may co ...
Pre-made tetracycline regulator (TetR) expression lentiviral
Pre-made tetracycline regulator (TetR) expression lentiviral

... TetR is used in tetracycline inducible expression. It binds to any inducible promoters that have incorporated Tet binding sequence to repress target expression. Target expression is induced once tetracycline is added. The added tetracycline binds to TetR, which releases TetR from target's promoter, ...
PDF
PDF

... Uncovering the direct regulatory targets of doublesex (dsx) and fruitless (fru) is crucial for an understanding of how they regulate sexual development, morphogenesis, differentiation and adult functions (including behavior) in Drosophila melanogaster. Using a modified DamID approach, we identified ...
gene_expression
gene_expression

... At each step, a gene is selected at random The distance between the gene’s expression profile and each cluster’s weight vector is calculated, and the cluster with closest weight vector becomes the winner The winner’s and its neighbors’ (according to the 2D mapping) weight vectors are adjusted to rep ...
HMMs for gene predictions.
HMMs for gene predictions.

... i  codons  f  codoni  max ...
Fine mapping of Restorer-of-fertility in pepper (Capsicum
Fine mapping of Restorer-of-fertility in pepper (Capsicum

... genes originated from the same ancestral gene that existed before the speciation of land plants. Finally, RFL genes show much higher rates of non-synonymous to synonymous substitutions than other PPR genes (Fujii et al. 2011). The rate of diversifying selection is highest on the first, third and six ...
form/activity - Science of Security
form/activity - Science of Security

... • “We know how to construct airplanes.” (lift and drag) • “..and to build engines.” (propulsion) • “Inability to balance/steer [is the] problem.” (control) • “When this one feature has been worked out, the age of flying will have arrived, for all other difficulties are of minor importance.” ...
The influence of genomic imprinting on brain
The influence of genomic imprinting on brain

... low ( < 0.5), compared to the probability for a maternally derived allele ( = 0.5) (Hurst & McVean, 1997). Thus, the male parent’s genetic interest in any future offspring of the female is decreased, as is the coefficient of relatedness between offspring of the same female (Haig, 2000; Haig & Westob ...
Differential Gene Expression in the Siphonophore
Differential Gene Expression in the Siphonophore

... tissue samples that were mapped to the references to quantify expression. We collected and compared expression data with three short-read expression workflows that differ in sample preparation, sequencing technology, and mapping tools. These workflows were Illumina mRNA-Seq, which generates sequence ...
Distinct functions of two olfactory marker protein genes derived from
Distinct functions of two olfactory marker protein genes derived from

... Background: Whole genome duplications (WGDs) have been proposed to have made a significant impact on vertebrate evolution. Two rounds of WGD (1R and 2R) occurred in the common ancestor of Gnathostomata and Cyclostomata, followed by the third-round WGD (3R) in a common ancestor of all modern teleosts ...
VegT activates Bix4 to specify endodermal
VegT activates Bix4 to specify endodermal

... The three germ layers of the amphibian embryo are established by mechanisms involving both cytoplasmic localisation and cellcell interactions (Harland and Gerhart, 1997). The localisation of cytoplasmic determinants occurs during oogenesis, when various mRNAs and proteins become differentially distr ...
Original Article Genetic and epigenetic association studies suggest
Original Article Genetic and epigenetic association studies suggest

... breast cancer risk (OR=1.59, 95% CI: 1.06 -2.39), compared to the homozygous common genotype. When stratified by menopausal status, the variant alleles of both rs11544382 (OR=1.82, 95% CI: 1.09-3.03) and rs34324334 (OR=1.76, 95% CI: 1.10-2.83) were significantly associated with breast cancer risk in ...
The genomic substrate for adaptive radiation in African cichlid fish
The genomic substrate for adaptive radiation in African cichlid fish

... while genes of the four East African cichlids were annotated solely by EVM/PASA with support from the O. niloticus Ensembl gene predictions. All annotation pipelines used assembled RNAseq data generated from several tissues from each of the sequenced species (See RNAsequencing – Sample source). All ...
click to - White Rose Research Online
click to - White Rose Research Online

Cloning and expression analysis of follicle
Cloning and expression analysis of follicle

Ds - e-Acharya
Ds - e-Acharya

... chromosome structure. Some of the most popular controlling elements found in maize are activatordissociation (Ac-Ds) system and suppressormutator (spm) system. The number, type and location of these elements are characteristic of each maize strain. These elements can be classified in to two classes- ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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