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Methylation Dynamics in the Early Mammalian Embryo: Implications
Methylation Dynamics in the Early Mammalian Embryo: Implications

... genes becomes dependent on their parental origin (Bartolomei and Tilghman 1997). Following the establishment of imprinting in the male and female germ lines, respectively, the two parental genomes exhibit functional differences at fertilization. Methylation of 5 -cytosine residues in CpG dinucleoti ...
Methylation Dynamics in the Early Mammalian Embryo - Beck-Shop
Methylation Dynamics in the Early Mammalian Embryo - Beck-Shop

Thyroid Hormone and Adipocyte Differentiation
Thyroid Hormone and Adipocyte Differentiation

GhMYB25-like: a key regulator of early cotton fiber development.
GhMYB25-like: a key regulator of early cotton fiber development.

The Classical Genetic Switch in Lambda Phage- Lysis and
The Classical Genetic Switch in Lambda Phage- Lysis and

... simple organism like the lambda phage. Systems biology approaches will help understand the function of specific modules of these regulatory domains and will help understand the kinetic behavior and quantitative picture of the genetic circuit of the lambda phage. ...
Harnessing gene expression to identify the genetic basis of drug
Harnessing gene expression to identify the genetic basis of drug

... Box 1 (A) Growth in the presence of a subset of drugs is represented by the heat map on the left (blue corresponds to low growth yield and yellow to high growth yield). Each row represents the data for a single drug (SMP10 is 1,9-pyrazoloanthone, DFI is diphenyliodonium and SK&F is SK&F 96365) and e ...
Regulation of secondary metabolism in streptomycetes
Regulation of secondary metabolism in streptomycetes

... role in A-factor synthesis, but more recent studies of BarX [44] and ScbA [29] suggest that the AfsA family of proteins may play complex regulatory roles rather than function as catalytic enzymes. The only gene identified to date with a proven role in g-butyrolactone synthesis is barS1, which encode ...
Germline Mutation in NLRP2 (NALP2) in a Familial
Germline Mutation in NLRP2 (NALP2) in a Familial

... MS-PCR suggesting that NLRP2 mutations may be associated with an incomplete failure of imprinting establishment and/or a partial failure of maintenance methylation at this DMR. Interestingly, investigation of a mouse knockout of ZFP57 has suggested a role in both the establishment of germline methyl ...
Active and Inactive Genes Locafize Preferentially in the Periphery of
Active and Inactive Genes Locafize Preferentially in the Periphery of

Molecular Biology Reports
Molecular Biology Reports

... antioxidant enzymes and low-molecular weight antioxidants. Particularly, to protect themselves against the toxic ROS that result from stress conditions including dehydration, plants possess very efficient defense mechanisms that include the expression and activation of genes related to intracellular ...
The agouti mouse model: an epigenetic
The agouti mouse model: an epigenetic

... around nucleosomes, covalent modifications of histone tails (e.g. acetylation, methylation, phosphorylation), and DNA methylation. The influence of regulatory small RNAs and micro RNAs on gene transcription is also increasingly recognized as a key mechanism of epigenetic gene regulation. Conventional ...
Harnessing gene expression to identify the genetic basis of drug
Harnessing gene expression to identify the genetic basis of drug

document
document

... Polygenic Inheritance •Polygenic inheritance occurs when there is more than one gene involved in a particular phenotypic trait. •Each loci involved can also have multiple alleles. •Examples in humans include height, skin pigmentation, weight, cleft palate, neural tube defects, intelligence, the Rhe ...
From Genes to Proteins
From Genes to Proteins

... should see that many three-letter combinations can be produced. Compare this exercise to the table in Figure 4. Ask students how the two compare. (In the exercise, letters are combined to form words, but in the table the letters stand for combinations of ...
comparing quantitative trait loci and gene expression data
comparing quantitative trait loci and gene expression data

... also miss some interesting genes (Wayne and Mclntyre, 2002). Second, the high level of experimental error and limitations of analysis in microarray data introduce mistakes in the identification of relevant genes. Finally, QTL studies include the entire genome including noncoding regions, while micro ...
splicing.pdf
splicing.pdf

... This is just a preview, you will explore some of these different uses in more detail in the activity that follows. • In the example above, alternative splicing was used to include only one of several versions of an exon into a final protein product. This allows many slightly different versions of th ...
The Caenorhabditis elegans NK-2 class
The Caenorhabditis elegans NK-2 class

... Fig. 1. The myo-2 enhancer contains multiple elements that cooperate to activate transcription. (A) To characterize the myo-2 enhancer, DNA fragments are cloned upstream of a myo-3::lacZ fusion, which is normally expressed only in body wall muscle. The resulting plasmids are injected into the germli ...
Genetica per Scienze Naturali aa 04
Genetica per Scienze Naturali aa 04

... The map obtained by recombination frequency analysis does not place the gene loci at specific places on the chromosome; it simply allows us to determine the positions of genes relative to one another (linkage groups). The small cluster of three genes could in theory be anywhere on the actual chromos ...
manuscript pdf
manuscript pdf

... Figure 1. Scanning Electron Microscopy of Flowers from Transgenic Arabidopsis Plants Expressing the DEF Gene. Some perianth organs were removed to show more clearly the reproductive organs. (A) Wild-type flower with first-whorl sepals (S), second-whorl petals (P), third-whorl stamens (T), and a four ...


... models of cultivation, intensive and extensive, have been used in the large-scale cultivation of Dunaliella salina. • D.salina has the eukaryotic post-translational processing for proteins, such as the formation of disulfide bond and glycosylation, which simplifies processing of the downstream of ge ...
Gene Section PAX2 (Paired box gene 2) Atlas of Genetics and Cytogenetics
Gene Section PAX2 (Paired box gene 2) Atlas of Genetics and Cytogenetics

... and urogenital tract. PAX2 contains a DNA binding paired domain, a truncated homeodomain, an octapeptide region and a carboxyl-terminal transactivation domain. ...
ARVO 2004 poster file
ARVO 2004 poster file

... vesicle-mediated transport /// regulation of JNK cascade regulation of transcription, DNA-dependent; apoptosis ----regulation of transcription, DNA-dependent fatty acid biosynthesis DNA replication /// DNA repair /// protein biosynthesis ----signal transduction --apoptosis;activation of NF-kappaB-in ...
The murine homologue of HIRA, a DiGeorge
The murine homologue of HIRA, a DiGeorge

... various laboratories. These attempts led to the isolation of DGCR3 and DGCR5. DGCR3 is an open reading frame (ORF) of 260 amino acids (aa) that is interrupted by the translocation breakpoint (21). However, no cDNAs were isolated and expression studies were only informative under low stringency condi ...
AthaMap web tools for database-assisted identification of
AthaMap web tools for database-assisted identification of

... The AthaMap database is based on the in silico determination of binding sites and does not distinguish between experimentally verified and predicted sites. Therefore, it is desirable to discriminate between higher and lower conserved binding sites. A criterion for the conservation of a site is the i ...
Population Differences in Transcript
Population Differences in Transcript

... expression data from the profiling of Epstein-Barr virus (EBV)transformed lymphoblastoid cell lines from the individuals in each CEU and YRI HapMap population [33] were obtained from the National Center for Biotechnology Information Gene Expression Omnibus (GEO) database under accession number GSE10 ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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