B-catenin
... •C-myc (red in (d) and (e)) was not expressed in islets of normal mice (marked by dotted lines and glucagon in green in (d)) • but was induced in islets and some ducts of high-fat fed mice (islets marked by glucagon in green). •C-myc expression is quantitated in (f). ...
... •C-myc (red in (d) and (e)) was not expressed in islets of normal mice (marked by dotted lines and glucagon in green in (d)) • but was induced in islets and some ducts of high-fat fed mice (islets marked by glucagon in green). •C-myc expression is quantitated in (f). ...
Slide 1
... presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the classes established. ...
... presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the classes established. ...
Letter Gene Survival and Death on the Human Y
... homologs. Although previous comparisons showed that X-linked genes are more broadly expressed than their functional Y homologs (Wilson and Makova 2009), it was unclear whether, among X-linked genes, those with functional Y homologs show different expression patterns than those without functional Y h ...
... homologs. Although previous comparisons showed that X-linked genes are more broadly expressed than their functional Y homologs (Wilson and Makova 2009), it was unclear whether, among X-linked genes, those with functional Y homologs show different expression patterns than those without functional Y h ...
Strategies for Improving Soluble Protein Production in E. coli
... Origins of error: Low tRNA availability mRNA secondary structure Translation rate too slow or too fast ...
... Origins of error: Low tRNA availability mRNA secondary structure Translation rate too slow or too fast ...
Integrative Genome-wide Analysis of the Determinants of RNA
... that have a potential for new biomarkers. We identified a subset of genes that show introns only observable in tumor but not in normal samples, ENCODE and GEUVADIS samples. In order to improve our understanding of the underlying genetic mechanisms of splicing variation we performed a large-scale ass ...
... that have a potential for new biomarkers. We identified a subset of genes that show introns only observable in tumor but not in normal samples, ENCODE and GEUVADIS samples. In order to improve our understanding of the underlying genetic mechanisms of splicing variation we performed a large-scale ass ...
Praktikum der Microarray-Datenanalyse
... the experiement performed • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a n ...
... the experiement performed • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a n ...
pdf
... amino acids from small dicarboxylic acids (components of the the citric acid cycle). If the cell has plenty of the product already (in the presence of the product), the the enzymes catalyzing its synthesis are not needed, and the operon encoding them is repressed. In the absence of the product, when ...
... amino acids from small dicarboxylic acids (components of the the citric acid cycle). If the cell has plenty of the product already (in the presence of the product), the the enzymes catalyzing its synthesis are not needed, and the operon encoding them is repressed. In the absence of the product, when ...
Article Selection Is No More Efficient in Haploid than in Diploid Life
... and only expressed in the diploid phase may be hidden from haploid selection, and thus may accumulate recessive deleterious or beneficial mutations without affecting haploid fitness (Shaw and Beer 1997; Otto 2004). In other words, diploid-specific genes should evolve more rapidly. This applies espec ...
... and only expressed in the diploid phase may be hidden from haploid selection, and thus may accumulate recessive deleterious or beneficial mutations without affecting haploid fitness (Shaw and Beer 1997; Otto 2004). In other words, diploid-specific genes should evolve more rapidly. This applies espec ...
Statistical analysis of DNA microarray data
... Which genes to use for normalization Housekeeping genes Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation These genes will be similarly expressed in all samples. Difficult to identify – need to be confirmed Affymetrix GeneC ...
... Which genes to use for normalization Housekeeping genes Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation These genes will be similarly expressed in all samples. Difficult to identify – need to be confirmed Affymetrix GeneC ...
model for Escherichia coli chromosome packaging supports
... need to be expressed in different concentrations in dependence of the genomic distance from their target genes and of the number of target genes regulated (20). Additionally, it was shown that expressed mRNAs largely display limited dispersion from their sites of transcription, which suggests that t ...
... need to be expressed in different concentrations in dependence of the genomic distance from their target genes and of the number of target genes regulated (20). Additionally, it was shown that expressed mRNAs largely display limited dispersion from their sites of transcription, which suggests that t ...
Developmental Psychobiology - Champagne Lab
... is double stranded, between 15 and 20 kb long, circular, intron-less, and contains typically 37 genes that encode ribosomal RNAs, transfer RNAs and subunits of the oxidative phosphorlyation pathway which are required for the regulation of energy metabolism. Across different cell types there is great ...
... is double stranded, between 15 and 20 kb long, circular, intron-less, and contains typically 37 genes that encode ribosomal RNAs, transfer RNAs and subunits of the oxidative phosphorlyation pathway which are required for the regulation of energy metabolism. Across different cell types there is great ...
Integrated Analysis of Microarray Data and Gene Function Information.
... some experimental conditions. The modules reflect the modular organization of the yeast transcription network. Here we use Homogeneity Analysis to present a global view of the relations between the modules and their connections to the underlying biological processes. We selected 72 modules that cont ...
... some experimental conditions. The modules reflect the modular organization of the yeast transcription network. Here we use Homogeneity Analysis to present a global view of the relations between the modules and their connections to the underlying biological processes. We selected 72 modules that cont ...
[Full text/PDF]
... The other two QTTs had positive effects on lint yield, indicating that high expression levels of these QTTs could result in increased lint yield. 2.2 Contributed genetic effects of the QTTs on lint yield and its component traits The predicted additive effects and the contributed effects of the six s ...
... The other two QTTs had positive effects on lint yield, indicating that high expression levels of these QTTs could result in increased lint yield. 2.2 Contributed genetic effects of the QTTs on lint yield and its component traits The predicted additive effects and the contributed effects of the six s ...
Deciphering the developmental program in the ascidian
... determined by interactions among multiple upstream regulators. It is difficult to determine how many upstream regulators exist for a certain gene. When considering the number of upstream regulators, researchers can exclude factors with a broad DNA-binding specificity from consideration. For the 211 ...
... determined by interactions among multiple upstream regulators. It is difficult to determine how many upstream regulators exist for a certain gene. When considering the number of upstream regulators, researchers can exclude factors with a broad DNA-binding specificity from consideration. For the 211 ...
You`re one in a googol: optimizing genes for protein expression
... Jordan 2008; Yang & Nielsen 2008). Whatever the evolutionary factors contributing to codon usage biases, the relevance of natural biases to designing genes for heterologous expression is not clear. Weak correlations between codon bias and expression of individual intragenomic genes have been observe ...
... Jordan 2008; Yang & Nielsen 2008). Whatever the evolutionary factors contributing to codon usage biases, the relevance of natural biases to designing genes for heterologous expression is not clear. Weak correlations between codon bias and expression of individual intragenomic genes have been observe ...
Invited Review: How sleep deprivation affects gene expression in
... postsynaptic neurotransmission machinery may represent a general compensatory response of the brain to the increased synaptic neurotransmission during wakefulness relative to sleep. In addition, the induction of at least some of these genes, such as GluR2, may more specifically mediate the occurrenc ...
... postsynaptic neurotransmission machinery may represent a general compensatory response of the brain to the increased synaptic neurotransmission during wakefulness relative to sleep. In addition, the induction of at least some of these genes, such as GluR2, may more specifically mediate the occurrenc ...
Tutorial: RNA-Seq Analysis Part II (Tracks): Non-Specific
... Figure 10: The dot in the scatter plot corresponding to the gene "Rps13" and the corresponding region in the trackm list "zoomed-to-selection". area showing the visible reads by grabbing at the bottom of the track's editor and dragging it downwards. You will get a view similar to that in figure 11. ...
... Figure 10: The dot in the scatter plot corresponding to the gene "Rps13" and the corresponding region in the trackm list "zoomed-to-selection". area showing the visible reads by grabbing at the bottom of the track's editor and dragging it downwards. You will get a view similar to that in figure 11. ...
Mef2 gene expression marks the cardiac and skeletal muscle
... MEF2 DNA-binding activity is also present in neonatal cardiac myocytes, indicating that MEF2 expression can be controlled independently of the skeletal muscle bHLH proteins (Zhu et al., 1991; Yu et al., 1992; Navankasattusas et al., 1992; Ianello et al., 1991). The majority of cardiac gene control r ...
... MEF2 DNA-binding activity is also present in neonatal cardiac myocytes, indicating that MEF2 expression can be controlled independently of the skeletal muscle bHLH proteins (Zhu et al., 1991; Yu et al., 1992; Navankasattusas et al., 1992; Ianello et al., 1991). The majority of cardiac gene control r ...
Chromosome Linkage and Mapping
... It is usually a simple matter to determine which of the gametes are recombinant. These are the gametes that are found in the lowest frequency. This is the direct result of the reduced recombination that occurs between two genes that are located close to each other on the same chromosome. Also by lo ...
... It is usually a simple matter to determine which of the gametes are recombinant. These are the gametes that are found in the lowest frequency. This is the direct result of the reduced recombination that occurs between two genes that are located close to each other on the same chromosome. Also by lo ...
209 Original Scientific Article THE INFLUENCE OF
... One of the main reason for the incorrect development of embryos derived from somatic cell nuclear transfer is caused by insufficient demethylation of injected somatic chromatin to a state comparable with an early embryonic nucleus. It is already known that the epigenetic enzymes transcription in ooc ...
... One of the main reason for the incorrect development of embryos derived from somatic cell nuclear transfer is caused by insufficient demethylation of injected somatic chromatin to a state comparable with an early embryonic nucleus. It is already known that the epigenetic enzymes transcription in ooc ...
Functional significance of the discordance between
... of integrated biological changes in cardiac myocyte size and function, as well as changes in LV structure and organization that allow for normalization of the LV end-diastolic pressure–volume (LVEDP-volume) relationship (reviewed in ref. 3). Although many of the individual components of reverse LV r ...
... of integrated biological changes in cardiac myocyte size and function, as well as changes in LV structure and organization that allow for normalization of the LV end-diastolic pressure–volume (LVEDP-volume) relationship (reviewed in ref. 3). Although many of the individual components of reverse LV r ...
AN INTEGRATED MAP OF CATTLE CANDIDATE GENES FOR
... candidate loci on chromosomes 7, 23, 19, 5 and 9 and the lowest on chromosome 28. The gene map shows mastitis candidate loci on all chromosomes except chromosome Y. ...
... candidate loci on chromosomes 7, 23, 19, 5 and 9 and the lowest on chromosome 28. The gene map shows mastitis candidate loci on all chromosomes except chromosome Y. ...
12859_2006_1447_MOESM4_ESM
... resulting data are provided. including summary, gene structure, transcripts, functional annotation, SAGE by disease, and EST expression by tissue and disease. Using over 5 million ESTs and over 139,000 mRNAs, ECgene identified 9,312 spliced genes in humans. Submission of the gene DDR1 yielded 7 spli ...
... resulting data are provided. including summary, gene structure, transcripts, functional annotation, SAGE by disease, and EST expression by tissue and disease. Using over 5 million ESTs and over 139,000 mRNAs, ECgene identified 9,312 spliced genes in humans. Submission of the gene DDR1 yielded 7 spli ...