Analyzing microRNA Data and Integrating microRNA with Gene
... regulate many genes, the PutativeGenes list will be much longer than the input microRNA list. The PutativeGenes list might be used for Biological Interpretation. Another useful way to examine the data would be to right-click on the Gene Symbol column (last one on the right) and select Create List w ...
... regulate many genes, the PutativeGenes list will be much longer than the input microRNA list. The PutativeGenes list might be used for Biological Interpretation. Another useful way to examine the data would be to right-click on the Gene Symbol column (last one on the right) and select Create List w ...
Full Text
... Alkaline phosphatase (AP) activity, a marker of endoderm differentiation (Fig. 4I) was detected in embryos developed from eggs injected with a high dose of Cs-HNF3 mRNA (Fig. 4J). To examine further whether overexpression of Cs-HNF3 leads to ectopic endoderm differentiation, we took advantage of cle ...
... Alkaline phosphatase (AP) activity, a marker of endoderm differentiation (Fig. 4I) was detected in embryos developed from eggs injected with a high dose of Cs-HNF3 mRNA (Fig. 4J). To examine further whether overexpression of Cs-HNF3 leads to ectopic endoderm differentiation, we took advantage of cle ...
The RNA world meets behavior: AfiI pre
... that can be generated from an edited gene. Another difference between editing and normal genetic variation is the potential for spatial and temporal regulation. Because an ADAR enzyme introduces modifications into mRNAs, editing is thus dependent on the amount and location of that protein. Indeed, d ...
... that can be generated from an edited gene. Another difference between editing and normal genetic variation is the potential for spatial and temporal regulation. Because an ADAR enzyme introduces modifications into mRNAs, editing is thus dependent on the amount and location of that protein. Indeed, d ...
iron-regulatory protein 1
... been previously described by Moeder et al. [20] and was named KO-661 [20]. Lines homozygous for the disruption were isolated, and used for further studies. When the mutants were grown in a greenhouse, or in hydroponic cultures under controlled conditions, they displayed no macroscopic phenotype. Fur ...
... been previously described by Moeder et al. [20] and was named KO-661 [20]. Lines homozygous for the disruption were isolated, and used for further studies. When the mutants were grown in a greenhouse, or in hydroponic cultures under controlled conditions, they displayed no macroscopic phenotype. Fur ...
IMPROVE SMALL RNA-MEDIATED GENE SILENCING
... perfectly dsRNA precursors and miRNAs derived from single-stranded RNA transcripts (transcribed from MIR genes) with imperfectly fold-back stem-loop structures. Endogenously expressed siRNAs (endo-siRNAs) can be further divided into several secondary classifications, including: heterochromatic siRNA ...
... perfectly dsRNA precursors and miRNAs derived from single-stranded RNA transcripts (transcribed from MIR genes) with imperfectly fold-back stem-loop structures. Endogenously expressed siRNAs (endo-siRNAs) can be further divided into several secondary classifications, including: heterochromatic siRNA ...
Gene Section ID4 (inhibitor of DNA binding 4, dominant negative helix-loop-helix protein)
... proteins act as trans-cription factors, ID genes are transcription repress-sors, modulating various functions. ID proteins play critical roles in early embryonic processes, growth, differentiation, senescence and apoptosis; they are also involved in angiogenesis. ID4 is expressed in the central nerv ...
... proteins act as trans-cription factors, ID genes are transcription repress-sors, modulating various functions. ID proteins play critical roles in early embryonic processes, growth, differentiation, senescence and apoptosis; they are also involved in angiogenesis. ID4 is expressed in the central nerv ...
WHITE PANICLE1, a Val-tRNA Synthetase
... phenotype during early leaf development. Seedlings showing the severe albino phenotype (wp1s) died when they reached the four-leaf stage (Fig. 1A, a–b; Supplemental Figure S1A), while wp1 seedlings showing the weak virescent phenotype (wp1w) could reach the flowering stage when they displayed white p ...
... phenotype during early leaf development. Seedlings showing the severe albino phenotype (wp1s) died when they reached the four-leaf stage (Fig. 1A, a–b; Supplemental Figure S1A), while wp1 seedlings showing the weak virescent phenotype (wp1w) could reach the flowering stage when they displayed white p ...
Expression of p53 Target Genes in the Early Phase of Long
... experimental model of synaptic plasticity. We have studied the expression of at least 50 genes that are transcriptionally regulated by p53, as well as other genes that are related to p53-dependent processes, in the early phase of LTP. Within 30 min after Schaffer collaterals (SC) tetanization, incre ...
... experimental model of synaptic plasticity. We have studied the expression of at least 50 genes that are transcriptionally regulated by p53, as well as other genes that are related to p53-dependent processes, in the early phase of LTP. Within 30 min after Schaffer collaterals (SC) tetanization, incre ...
Human karyotype
... female has twice the genetic material than males for genes on the X chromosome dosage compensation: adjust for levels of gene expression in humans and many organisms dosage compensation occurs by X-inactivation the X-chromosome inactivated in each cell is randomly chosen can observe inacti ...
... female has twice the genetic material than males for genes on the X chromosome dosage compensation: adjust for levels of gene expression in humans and many organisms dosage compensation occurs by X-inactivation the X-chromosome inactivated in each cell is randomly chosen can observe inacti ...
NeuroGeM, a knowledgebase of genetic modifiers
... Modifiers can be grouped into aggregation modifiers and toxicity modifiers depending on the quantification method: the primary effect of aggregation modifiers is to increase or decrease aggregates while the primary effect of toxicity modifiers is to change the phenotype eventually leading to cell de ...
... Modifiers can be grouped into aggregation modifiers and toxicity modifiers depending on the quantification method: the primary effect of aggregation modifiers is to increase or decrease aggregates while the primary effect of toxicity modifiers is to change the phenotype eventually leading to cell de ...
Vertebrate genomics : More fishy tales about Hox genes
... probably duplicated twice, giving the four Hox clusters (clusters A–D) seen in the human and mouse genomes. These duplications from one to two, and then from two to four, clusters probably occurred, not as tandem gene duplications but either as a result of individual chromosome duplications or, more ...
... probably duplicated twice, giving the four Hox clusters (clusters A–D) seen in the human and mouse genomes. These duplications from one to two, and then from two to four, clusters probably occurred, not as tandem gene duplications but either as a result of individual chromosome duplications or, more ...
From bedside to bench: how to analyze a splicing
... removal of introns from pre/messenger RNA by splicing is a very complex step in eukaryotic gene expression which necessitates a more widespread use than previously thought of cis and trans-acting elements in order to identify the exon. As a result, the widespread occurrence of this class of mutation ...
... removal of introns from pre/messenger RNA by splicing is a very complex step in eukaryotic gene expression which necessitates a more widespread use than previously thought of cis and trans-acting elements in order to identify the exon. As a result, the widespread occurrence of this class of mutation ...
HbF inducers
... been shown to induce HbF synthesis in vitro ● Some studies have been carried out using valproic acid, a compound related to short fatty acid derivatives, reported increased HbF levels ...
... been shown to induce HbF synthesis in vitro ● Some studies have been carried out using valproic acid, a compound related to short fatty acid derivatives, reported increased HbF levels ...
MicroRNA Analysis
... of an miRNA, i.e. in which host gene it is encoded, its expression in different tissues and its known or proposed function, its potential target genes including Gene Ontology annotation, as well as miRNA families and proteins known to be involved in miRNA processing. ...
... of an miRNA, i.e. in which host gene it is encoded, its expression in different tissues and its known or proposed function, its potential target genes including Gene Ontology annotation, as well as miRNA families and proteins known to be involved in miRNA processing. ...
IGA 8/e Chapter 4
... 14. If only two of the three genes are linked, the data can still be grouped, but the grouping will differ from that mentioned in (12) above. In this situation, the unlinked gene will show independent assortment with the two linked genes. There will be one class composed of four phenotypes in approx ...
... 14. If only two of the three genes are linked, the data can still be grouped, but the grouping will differ from that mentioned in (12) above. In this situation, the unlinked gene will show independent assortment with the two linked genes. There will be one class composed of four phenotypes in approx ...
comparative evolution and development of the butterfly eyespot and
... pigment (exe. Koch et al. 1998). These patterns have proven amenable to a detailed developmental characterization, classically through surgical manipulations of pupal wings (e.g., Nijhout 1980, French and Brakefield 1995), and more recently through the study of gene expression patterns (e.g., Brakef ...
... pigment (exe. Koch et al. 1998). These patterns have proven amenable to a detailed developmental characterization, classically through surgical manipulations of pupal wings (e.g., Nijhout 1980, French and Brakefield 1995), and more recently through the study of gene expression patterns (e.g., Brakef ...
Tombola, a tesmin/TSO1-family protein, regulates
... mutants display defects in chromatin organisation. Finally, a small subset of genes are much more dependent on topi and/or achi/vis than on aly or comr for their transcription (Jiang and White-Cooper, 2003; Perezgazga et al., 2004). To find further transcriptional regulators in primary spermatocytes ...
... mutants display defects in chromatin organisation. Finally, a small subset of genes are much more dependent on topi and/or achi/vis than on aly or comr for their transcription (Jiang and White-Cooper, 2003; Perezgazga et al., 2004). To find further transcriptional regulators in primary spermatocytes ...
MEF2 activity during embryogenesis - Development
... et al., 1989; Cserjesi and Olson, 1991). Whereas a single MEF2-binding site is transcriptionally inactive, when the ...
... et al., 1989; Cserjesi and Olson, 1991). Whereas a single MEF2-binding site is transcriptionally inactive, when the ...
Multi-petal cyclamen flowers produced by
... Figure 2 | Phenotypes of 35S:CpAG1-SRDX and 35S:CpAG2-SRDX Arabidopsis. (a) A flower of wild-type Arabidopsis. (b) A flower of 35S:CpAG1SRDX Arabidopsis with petaloid stamens (red arrowhead). (c) A double flower of 35S:CpAG2-SRDX plant. Inside the carpel is shown by dissection. Solid arrow and dashe ...
... Figure 2 | Phenotypes of 35S:CpAG1-SRDX and 35S:CpAG2-SRDX Arabidopsis. (a) A flower of wild-type Arabidopsis. (b) A flower of 35S:CpAG1SRDX Arabidopsis with petaloid stamens (red arrowhead). (c) A double flower of 35S:CpAG2-SRDX plant. Inside the carpel is shown by dissection. Solid arrow and dashe ...
Reliable classification of two-class cancer data using evolutionary
... The DNA microarray is an orchestrated arrangement of thousands of different single-stranded DNA probes in the form of cDNAs or oligonucleotides immobilized onto a glass or silicon substrate. The underlying principle of microarray technology is the hybridization or the base pairing of nucleotides. An ...
... The DNA microarray is an orchestrated arrangement of thousands of different single-stranded DNA probes in the form of cDNAs or oligonucleotides immobilized onto a glass or silicon substrate. The underlying principle of microarray technology is the hybridization or the base pairing of nucleotides. An ...
Gene Section LMO2 (LIM domain only 2 (rhombotin-like 1))
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
Clustering of mandibular organ-inhibiting hormone and moult
... directly or following sub-cloning into Bluescript vector) by using M13 forward and reverse primers, together with gene-specific primers. In addition, the sequence of continuous regions of 8.5 kb from a representative group 1 clone (l1) and 4.3 kb from a representative group 4 clone (l12) were determ ...
... directly or following sub-cloning into Bluescript vector) by using M13 forward and reverse primers, together with gene-specific primers. In addition, the sequence of continuous regions of 8.5 kb from a representative group 1 clone (l1) and 4.3 kb from a representative group 4 clone (l12) were determ ...
Article Old but Not (So) Degenerated—Slow
... evolution, we performed ostrich transcriptome sequencing and studied genes from the nonrecombining region of the W chromosome. Fourteen gametologous gene pairs present on the W chromosome and Z chromosome were identified, with synonymous sequence divergence of 0.027–0.177. The location of these gene ...
... evolution, we performed ostrich transcriptome sequencing and studied genes from the nonrecombining region of the W chromosome. Fourteen gametologous gene pairs present on the W chromosome and Z chromosome were identified, with synonymous sequence divergence of 0.027–0.177. The location of these gene ...