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Evolution of synonymous codon usage in metazoans Laurent Duret
Evolution of synonymous codon usage in metazoans Laurent Duret

... rules out the possibility that the relationship between codon bias and gene expression is due to a transcriptioncoupled mutational process [8•] and thus shows directly that synonymous codon usage is shaped by natural selection in these two invertebrates. Few experimental data on the cellular abundan ...
The Optimal Discovery Procedure II: Applications to Comparative
The Optimal Discovery Procedure II: Applications to Comparative

... A microarray measures the abundance of mRNA transcripts of thousands of genes from a single biological sample (1, 2). Of much recent interest has been the problem of identifying genes that are differentially expressed across varying biological conditions based on microarray data (3). It is now possi ...
Database of cattle candidate genes and genetic markers for
Database of cattle candidate genes and genetic markers for

... A cattle database of candidate genes and genetic markers for milk production and mastitis has been developed to provide an integrated research tool incorporating different types of information supporting a genomic approach to study lactation, udder development and health. The database contains 943 g ...
Archives of Microbiology
Archives of Microbiology

... from A. azotica and Anabaena variabilis shared identities of 93% on DNA and 98% on amino acid levels, whereas identity values between the Anabaena sp. CH1 and A. variabilis sequences amounted to only 77% for the nucleotides and 73% for the amino acids. VnfD and vnfG, which are separate genes in othe ...
The novel Cer-like protein Caronte mediates the establishment of
The novel Cer-like protein Caronte mediates the establishment of

The Interplay of Temperature and Genotype on Patterns
The Interplay of Temperature and Genotype on Patterns

... 5). Further support for this lack of congruence comes from ROC for exon expression intensities as well as a difference in GO term enrichment for genes with significant genetic differences and plasticity (Figure H, File S1). Out of all splicing events that differed between the strains for a given temp ...
Chapter 3
Chapter 3

... domain (%1) and the WR motif (%2) at the right of the sequence. Helobdella is missing the WR motif (our observation). Other vertebrate bHLH and WR sequences (chick, rat and human) are identical to the mouse. The Patella bHLH domain is most similar to the chordate domains (score of at least 83%) and ...
The microRNAs of Caenorhabditis elegans
The microRNAs of Caenorhabditis elegans

... lin-4 was the natural candidate to coordinate the temporally graded expression of LIN-14. Genetic epistasis analysis showed that a wild type copy of lin-14 was required to mediate the lin-4 heterochronic phenotype, indicating lin-4 lay upstream of lin-14 [27]. Moreover, the temporally graded protein ...
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Document

... Enzyme classification (EC) numbers Phenotype information  Alleles  Gene knockouts  RNAi knockdowns Expression data  EST libraries (source of RNA material)  Microarrays  SAGE tags ...
ARGONAUTE1 Acts in Arabidopsis Root Radial
ARGONAUTE1 Acts in Arabidopsis Root Radial

... Mette et al. 2002, Park et al. 2002, Reinhart et al. 2002). Largescale sequencing approaches have revealed numerous miRNAs and their target genes (Rajagopalan et al. 2006, Fahlgren et al. 2007). Processed from imperfectly complementary stem–loop precursor RNAs (Bartel 2004), miRNAs regulate gene exp ...
A Complex Suite of Forces Drives Gene Traffic from Drosophila X
A Complex Suite of Forces Drives Gene Traffic from Drosophila X

... et al. 2004; Potrzebowski et al. 2008). The autosomal copies of these paralogs tend to be testis expressed, suggesting that these new genes are preferentially retained because they allow for escape from X-inactivation. However, there is still a deficiency of genes with male-biased expression on Dros ...
PDF 743ko
PDF 743ko

13-1
13-1

... In prokaryotes, RNA synthesis and protein synthesis take place in the cytoplasm. In eukaryotes, RNA is produced in the cell’s nucleus and then moves to the cytoplasm to play a role in the production of protein. Our focus here is on transcription in eukaryotic cells. Transcription requires an enzyme, ...
RNA-based regulation of genes of tryptophan synthesis
RNA-based regulation of genes of tryptophan synthesis

... Regulatory subtleties abound, however, therefore each event—at each stage—is not absolute. Other regulatory processes influence trp mRNA synthesis and survival, trp coding region translation, trp enzyme function and turnover, and trp enzyme activity (Landick and Yanofsky 1987; Yanofsky and Crawford ...
Gene prediction and Genome Annotation
Gene prediction and Genome Annotation

... • New genomes require new approaches or at least require re-optimilisation of software • Isoforms (NGS data) • “New genes” , eg. lncRNAs, anti-sense RNAs, … • New “organisation” of genes – Overlapping genes (transcript, CDS) – Nested genes ...
Genetic polymorphisms of vein wall remodeling in chronic venous
Genetic polymorphisms of vein wall remodeling in chronic venous

... From www.bloodjournal.org by guest on June 15, 2017. For personal use only. GENETIC POLYMORPHISMS IN CHRONIC VENOUS DISEASE ...
Occurrence of phosphate acquisition genes in Prochlorococcus cells
Occurrence of phosphate acquisition genes in Prochlorococcus cells

... the Sargasso Sea (as represented in the World Ocean Database). However, many samples and strains do not originate from such extremely low-P environments, but still do not show any relationship between genome content and N/P ratio. This suggests that the concentration of phosphate per se controls the ...
Real time PCR based determination of gene copy numbers in
Real time PCR based determination of gene copy numbers in

... Nevertheless, recent studies reported even higher expression rates when the target gene was under the control of deletion variants of the AOX1 promoter [3] or in some cases also with the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter (PGAP) [4]. Depending on the target gene, high cop ...
Evolution 2010 Wilkins
Evolution 2010 Wilkins

... will be selected solely on the basis of its effect on the patrilineal fitness. If we consider a single locus in isolation, this outcome is unproblematic, and most likely indistinguishable from the evolutionary end point that would be reached by an unimprinted locus, because the phenotypes that maxim ...
Familial nonrandom inactivation linked to the X inactivation
Familial nonrandom inactivation linked to the X inactivation

... out subsequent cell divisions and, by this process, the dosage of proteins encoded by genes on the X chromosome is equalised in males and females. The choice of which of the two X chromosomes is the active one is usually random. Although stochastic events may account for a less than equal distributi ...
Operon review
Operon review

... INACTIVE (Circle one) INACTIVE (Circle one) ...
Mitochondrial Transcript Processing and Restoration of Male Fertility
Mitochondrial Transcript Processing and Restoration of Male Fertility

... ping experiments with guanylyl transferase identified the one known exception to this hypothesis; the 1.85 kb transcript is a primary (initiated) transcript and hence not the result of RNA processing ( Kennell and Pring 1989). Plants segregating for the Rf1, Rf8, or Rf* restorers accumulate novel T- ...
Identification of Full and Partial Class Relevant Genes
Identification of Full and Partial Class Relevant Genes

... classification problems. Signal-to-noise ratio [1], t-test [2], between-groups to within-groups ratio [3], support vector machine (SVM) based on recursive feature elimination method [4], and least squares bound method [5], etc. are among those applicable mainly to two-class problems. Microarray data ...
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... RNA-Seq Lab v5 | Radhika S. Khetani ...
PHANTASTICA Regulates Development of the Adaxial Mesophyll in
PHANTASTICA Regulates Development of the Adaxial Mesophyll in

... 1996). The Arabidopsis studies show that several KNOX genes, including KNAT1/BREVIPEDICELLUS (BP), KNAT2, and KNAT6, are ectopically expressed in the absence of AS1 function. This concerted response makes it uncertain as to which KNOX gene causes the phenotype, and the functional overlap of KNOX gen ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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