Evolutionary relationships of the Tas2r receptor gene families in
... (ftp://ftp.ncbi.nlm.nih.gov/blast). HSPs found by the same query sequence, and lying in proximity to each other on a single chromosome, were assembled into complete genes using the publicly available software GeneWise from the Wise2 package by Ewan Birney at the Sanger Centre, Hinxton, UK (http://ww ...
... (ftp://ftp.ncbi.nlm.nih.gov/blast). HSPs found by the same query sequence, and lying in proximity to each other on a single chromosome, were assembled into complete genes using the publicly available software GeneWise from the Wise2 package by Ewan Birney at the Sanger Centre, Hinxton, UK (http://ww ...
Networks in leaf development
... molecular networks that are involved in many different aspects of leaf development. This review aims only to spotlight several of the more recent studies that have contributed to our understanding of the mechanisms that regulate leaf initiation, ground-plan patterning and specification of final form ...
... molecular networks that are involved in many different aspects of leaf development. This review aims only to spotlight several of the more recent studies that have contributed to our understanding of the mechanisms that regulate leaf initiation, ground-plan patterning and specification of final form ...
RT-PCR Analysis - Shiu Lab - Michigan State University
... expression of these 23 PGs in a T87 suspension culture cell line that had been previously shown to have >60% genes expressed (24). Only one PG (At2g43860) was detected. To rule out the possibility of faulty primer designs, a second primer set was designed for each of these 23 PGs, but none led to d ...
... expression of these 23 PGs in a T87 suspension culture cell line that had been previously shown to have >60% genes expressed (24). Only one PG (At2g43860) was detected. To rule out the possibility of faulty primer designs, a second primer set was designed for each of these 23 PGs, but none led to d ...
Full Text - The International Journal of Developmental Biology
... In the mouse. the initial distribution of the Pax2gene transcripts is in postmitotic cells on both sides of the sulcus limitans of the neural tube, and later in the intermediate zone of the spinal cord, myelencephalon and metencephalon (Names at af., 1990; Asano and Gruss. 1992). Pax2 is also expres ...
... In the mouse. the initial distribution of the Pax2gene transcripts is in postmitotic cells on both sides of the sulcus limitans of the neural tube, and later in the intermediate zone of the spinal cord, myelencephalon and metencephalon (Names at af., 1990; Asano and Gruss. 1992). Pax2 is also expres ...
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... (1) The 3'-OH of the guanine nucleotide is the nucleophile that attacks and joins to the 5' phosphate of the first nucleotide of the intron. (2) This leaves the 3'-OH of the last nucleotide of the upstream exon available to attack and join the 5' phosphate of the first nucleotide of the downstream e ...
... (1) The 3'-OH of the guanine nucleotide is the nucleophile that attacks and joins to the 5' phosphate of the first nucleotide of the intron. (2) This leaves the 3'-OH of the last nucleotide of the upstream exon available to attack and join the 5' phosphate of the first nucleotide of the downstream e ...
Supplementary Data File Supplementary Figures Figure S1
... reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category. B. The count distribution of Pathway 1 contains a total of 100 genes from the dataset. From these 100 g ...
... reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category. B. The count distribution of Pathway 1 contains a total of 100 genes from the dataset. From these 100 g ...
Complex Inheritance of the 5-Lipoxygenase Locus
... from both mouse and human studies, we reasoned that the differing conclusions drawn from this study may be due to the complexity of the 5LO locus. If the chromosome 6 region flanking the 5LO gene contains other genes that influence atherosclerosis or aneurysm development, then studies of the 5LO kno ...
... from both mouse and human studies, we reasoned that the differing conclusions drawn from this study may be due to the complexity of the 5LO locus. If the chromosome 6 region flanking the 5LO gene contains other genes that influence atherosclerosis or aneurysm development, then studies of the 5LO kno ...
Specification of unique neuronal sub-types by integration of positional and temporal cues
... unload their content consisting of neurotransmitters into the synaptic cleft. There are many different neurotransmitters (GABA, Acetylcholine etc) identified, and they will dictate if the interneuron is inhibitory or excitatory. These molecules will bind to an appropriate receptor located on the pos ...
... unload their content consisting of neurotransmitters into the synaptic cleft. There are many different neurotransmitters (GABA, Acetylcholine etc) identified, and they will dictate if the interneuron is inhibitory or excitatory. These molecules will bind to an appropriate receptor located on the pos ...
QSTAR - Institute of Bioinformatics
... multiple conditions can only be detected if transcript is DE ...
... multiple conditions can only be detected if transcript is DE ...
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... echinoderms, endomesodermal set-aside cells produce the tripartite coeloms from which the mesodermal components of the adult body plan arise. These are the anterior coelom or protocoel, paired middle coeloms or mesocoels and paired posterior coeloms or metacoels; these coeloms are called the axocoel ...
... echinoderms, endomesodermal set-aside cells produce the tripartite coeloms from which the mesodermal components of the adult body plan arise. These are the anterior coelom or protocoel, paired middle coeloms or mesocoels and paired posterior coeloms or metacoels; these coeloms are called the axocoel ...
Transcript Isoform Differences Across Human Tissues Are
... isoforms can behave like completely distinct proteins when considering their proteinprotein interaction capabilities 15 . Recently, it has been reported that a large majority of alternatively spliced RNAs bind to ribosomes 16 , which suggests that most of them could be translated into proteins and t ...
... isoforms can behave like completely distinct proteins when considering their proteinprotein interaction capabilities 15 . Recently, it has been reported that a large majority of alternatively spliced RNAs bind to ribosomes 16 , which suggests that most of them could be translated into proteins and t ...
GIN Transposons: Genetic Elements Linking Retrotransposons and
... often essential, genes of the hosts derive from different classes of mobile sequences (reviewed by Volff 2006; Dooner and Weil 2007; Feschotte and Pritham 2007; Jurka et al. 2007). The emergence of many of these novel genes follows simple patterns. For example, the insertion of mobile sequences may ...
... often essential, genes of the hosts derive from different classes of mobile sequences (reviewed by Volff 2006; Dooner and Weil 2007; Feschotte and Pritham 2007; Jurka et al. 2007). The emergence of many of these novel genes follows simple patterns. For example, the insertion of mobile sequences may ...
Manipulating the Plasmodium Genome
... interfering’ RNAs (21-23 nucleotide fragments), which guide the cleavage of homologous mRNA by the silencing complex RISC (Hammond et al., 2001; Sharp, 2001). This evolutionarily conserved pathway, which may be part of a basic surveillance system that degrades transposon or viral messages, has alrea ...
... interfering’ RNAs (21-23 nucleotide fragments), which guide the cleavage of homologous mRNA by the silencing complex RISC (Hammond et al., 2001; Sharp, 2001). This evolutionarily conserved pathway, which may be part of a basic surveillance system that degrades transposon or viral messages, has alrea ...
Specific Combinations of Zein Genes and Genetic Backgrounds
... and the H2 are almost undetectable; in Wo2T, Moo2R, and Yo2It they are severely reduced; in No2It, Xo2It, and 33o2It the H2 is absent, whereas the H1 is only partially affected in the first two lines and almost unaffected in the third. As in O2 lines, in the o2 genotypes the pattern that occurs at m ...
... and the H2 are almost undetectable; in Wo2T, Moo2R, and Yo2It they are severely reduced; in No2It, Xo2It, and 33o2It the H2 is absent, whereas the H1 is only partially affected in the first two lines and almost unaffected in the third. As in O2 lines, in the o2 genotypes the pattern that occurs at m ...
Depleting Gene Activities in Early Drosophila Embryos
... An example of a Mat&Zyg gene that yields diverse phenotypes when it is depleted at different stages of development is the D-Raf serine-threonine kinase (Perrimon et al. 1985; Ambrosio et al. 1989; see review by Duffy and Perrimon 1994). D-raf mutant offspring derived from heterozygous females die du ...
... An example of a Mat&Zyg gene that yields diverse phenotypes when it is depleted at different stages of development is the D-Raf serine-threonine kinase (Perrimon et al. 1985; Ambrosio et al. 1989; see review by Duffy and Perrimon 1994). D-raf mutant offspring derived from heterozygous females die du ...
Attanasio et al.
... Glis2lacZ/lacZ mutant kidneys demonstrated that at 8 weeks, the hallmarks of NPHP were already present and were very pronounced at 6 months6. First, there was diffuse tubulointerstitial cell infiltration with interstitial fibrosis and deposition of collagen throughout the kidney. Second, there was t ...
... Glis2lacZ/lacZ mutant kidneys demonstrated that at 8 weeks, the hallmarks of NPHP were already present and were very pronounced at 6 months6. First, there was diffuse tubulointerstitial cell infiltration with interstitial fibrosis and deposition of collagen throughout the kidney. Second, there was t ...
MAMMALS THAT BREAK THE RULES:Genetics of Marsupials and
... offer informative variation on inactivation and even on the role of the X and Y in sex determination. The X chromosome is unique in the genome because of its extreme conservation and the inactivation of one X in females. Ohno showed three decades ago that among eutherian mammals, the X chromosome wa ...
... offer informative variation on inactivation and even on the role of the X and Y in sex determination. The X chromosome is unique in the genome because of its extreme conservation and the inactivation of one X in females. Ohno showed three decades ago that among eutherian mammals, the X chromosome wa ...
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... material Fig. S2B,D), which could be an indirect effect, but CDK9 has been reported to phosphorylate Ser5 in human cells (GloverCutter et al., 2009). Decreased Ser2-P after cdk-12 knockdown could be an indirect result of increased Pol II CTD phosphatase activity. Knockdown of the best characterized ...
... material Fig. S2B,D), which could be an indirect effect, but CDK9 has been reported to phosphorylate Ser5 in human cells (GloverCutter et al., 2009). Decreased Ser2-P after cdk-12 knockdown could be an indirect result of increased Pol II CTD phosphatase activity. Knockdown of the best characterized ...
How were introns inserted into nuclear genes?
... A group II intron could mutate into a classical intron. (a) Proposed sequence of about intron insertion19, and group I events. (b) Example of a group II intron (from Ref. 22) which would have introns are now known to insert then> classical splice signals given a single-base mutation ('). selves (see ...
... A group II intron could mutate into a classical intron. (a) Proposed sequence of about intron insertion19, and group I events. (b) Example of a group II intron (from Ref. 22) which would have introns are now known to insert then> classical splice signals given a single-base mutation ('). selves (see ...
Gene Section DLX6 (distal-less homeobox 6) Atlas of Genetics and Cytogenetics
... This disruption has been found to be finely tuned during a surprisingly short timeframe spanning a critical period of neurulation. This exposure creates a functional invalidation of Dlx5/Dlx6-controlled cranio-facial morphogenesis (reviewed in Gitton et al., 2010); ii) the food contaminant ochratoxi ...
... This disruption has been found to be finely tuned during a surprisingly short timeframe spanning a critical period of neurulation. This exposure creates a functional invalidation of Dlx5/Dlx6-controlled cranio-facial morphogenesis (reviewed in Gitton et al., 2010); ii) the food contaminant ochratoxi ...
Cluster Analysis in DNA Microarray Experiments
... View clustering as a deterministic rule that can be applied to parameters (or estimates thereof) of the distribution of gene expression measures. Parameters of interest include covariances between the expression measures of different genes. The parametric bootstrap can be used to study distributional ...
... View clustering as a deterministic rule that can be applied to parameters (or estimates thereof) of the distribution of gene expression measures. Parameters of interest include covariances between the expression measures of different genes. The parametric bootstrap can be used to study distributional ...
Investigation of Four Genes Responsible for Autosomal Recessive
... protein EphA2 is an epithelial cell kinase that interacts with membrane-bound ephrin ligands, which play an important role in morphogenesis and in numerous developmental processes [22]. For the first time, it was reported responsible for autosomal dominant cataracts (ADCC) and recently it was implic ...
... protein EphA2 is an epithelial cell kinase that interacts with membrane-bound ephrin ligands, which play an important role in morphogenesis and in numerous developmental processes [22]. For the first time, it was reported responsible for autosomal dominant cataracts (ADCC) and recently it was implic ...