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1Department of Hematology, 2Department of Dermatology, Leiden
1Department of Hematology, 2Department of Dermatology, Leiden

Article 1 Title: The pseudoautosomal regions of the U/V sex
Article 1 Title: The pseudoautosomal regions of the U/V sex

... recombining region is usually not lost completely and it is thought that most species retain a PAR because homologous recombination in this region plays a critical role in chromosomal pairing and segregation during meiosis [4,5]. Moreover, there are situations where sexually antagonistic forces may ...
GENE NUMBER, KIND, AND SIZE IN DROSOPHILA The
GENE NUMBER, KIND, AND SIZE IN DROSOPHILA The

... new heritable characters. In order that the problem may be sharply defined, we shall confine the discussion to data bearing upon the kind and size of the genes present in an animal organism. The approach lies in a knowledge of the physical characteristics of X-rays in relation to their biological ef ...
3- PARTE I Comparative cytogenetic mapping of Sox2 and
3- PARTE I Comparative cytogenetic mapping of Sox2 and



... Expression patterns of MSTN isoforms in fish are different from that of mammals and different from each other. MSTN1 is expressed in many tissues in fish [13, 17, 24], whereas MSTN2 expression is primarily confined to the brain [12]. In silver sea bream, MSTN1 mRNA was detected in white and red musc ...
HapTree-X: An integrative Bayesian framework for haplotype
HapTree-X: An integrative Bayesian framework for haplotype

Ectopic segmentation gene expression and
Ectopic segmentation gene expression and

... segmentation genes and the rapidity with which they organize themselves make it clear that pattern cannot be the result of strictly sequential gene action. As gene interactions become more complicated, in number and temporal complexity, it becomes increasingly difficult to distinguish between direct ...
Reconstruction of a Functional Human Gene Network, with an
Reconstruction of a Functional Human Gene Network, with an

... loci identified in linkage studies is difficult because these loci may contain hundreds of genes. However, in any disorder, most of the disease genes will be involved in only a few different molecular pathways. If we know something about the relationships between the genes, we can assess whether som ...
Imprinting capacity of gamete lineages in C. elegans
Imprinting capacity of gamete lineages in C. elegans

... the germline-sex-specific modification of the X chromosome in C. elegans. In their study, they observed a difference in chromatin state in the zygote between the spermatogenesis-derived and oogenesis-derived X chromosome. The differential chromatin marks persisted up to the 20-cell stage of embryoge ...
Application of Bruchin B to pea pods results in
Application of Bruchin B to pea pods results in

... either bruchin treatment-specific or genotype-specific (data not shown). One of these, designated GT13, obtained with the primer combination T11GT/OPA-13, appeared to have been derived from a gene that was up-regulated by bruchin treatment, with stronger up-regulation in Np/Np pods than in np/np pod ...
Gadd45g Is Essential for Primary Sex Determination, Male
Gadd45g Is Essential for Primary Sex Determination, Male

... usually contained mainly interstitial cells and multiple primordial follicles, but no other stages of oocyte and follicle development (Fig. 1Q,W). All fertility-tested XY-F mice were infertile. The third group consisted of intersex mice (XY-intersex, Fig. 1F,L) with male, female, or ambiguous extern ...
Functional SNPs in the SCGB3A2 promoter are
Functional SNPs in the SCGB3A2 promoter are

... additional markers around D5s436 were used, a maximum two-point LOD score of 4.31 and a maximum multipoint LOD score of 4.12 were obtained for marker D5s2090 (11). Interestingly, from a dataset of 123 Japanese sibling pairs, the 5q31 locus was also linked with autoimmune thyroid disease (AITD), incl ...
A CRISPR-based yeast two-hybrid system for investigating
A CRISPR-based yeast two-hybrid system for investigating

... Design and construction of a yeast two-hybrid system to study RNA-protein binding We constructed the yeast strain used for CARRY two-hybrid, “CARRYeast (1.0),” by integrating a dCas9 expression cassette4 in the genome of a previously published yeast twohybrid strain, L40, w ...
TYPES OF GENE ACTION The interaction with in alleles of gene
TYPES OF GENE ACTION The interaction with in alleles of gene

Relationships Between RNA Polymerase II Activity and Spt
Relationships Between RNA Polymerase II Activity and Spt

... Extensive molecular characterization of intragenic cryptic transcription and control of the yeast gene SER3 repression by transcription and transcription-dependent chromatin control (by the SRG1 noncoding RNA that overlaps the SER3 promoter) have revealed principles by which transcription units may ...
A CRISPR-based yeast two-hybrid system for investigating
A CRISPR-based yeast two-hybrid system for investigating

... Design and construction of a yeast two-hybrid system to study RNA-protein binding We constructed the yeast strain used for CARRY two-hybrid, “CARRYeast (1.0),” by integrating a dCas9 expression cassette4 in the genome of a previously published yeast twohybrid strain, L40, w ...
Negative regulation of defense responses in Arabidopsis by two
Negative regulation of defense responses in Arabidopsis by two

... less than twofold in the wild-type plants (Figure 3e,f), suggesting that induction of PR-1 in the double mutant is quicker than that in the wild-type plants. Two days after INA induction, the PR-1 level is similar in the npr3-1 npr4-3 and wild-type plants. The npr3-1 npr4-3 double mutant shows enhan ...
Principals of General Zoology (Zoo-103)
Principals of General Zoology (Zoo-103)

... chromosomes. In the diploid state, members of the same chromosome pair are referred to as homologous chromosome, or homologs. One member of each pair comes from each parent.  Humans have 23 homologous chromosome pairs, which is often expressed as 2n=46. This expression indicate that humans are dipl ...
Twinning and Embryonic Left-Right Asymmetry
Twinning and Embryonic Left-Right Asymmetry

... body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exhibits when viewed from the outside. Interestingly though, the internal organs of most animals reveal an individually and evolutionarily conserved asymme ...
Attachment PDF Icon
Attachment PDF Icon

... Short  tags  used  in  GIS-­‐PET  sequencing  provide  signatures  of  the  5'  start  and  the  3'   end  of  individual  mRNA  transcripts,  thus  demarcating  the  first  and  last  exon,  and   contain  enough  coding  information   ...
Genome position and gene amplification | SpringerLink
Genome position and gene amplification | SpringerLink

... and rare sites (RFS), which appear only in certain individuals. The sites are further distinguished by agents used to induce expression, which include aphidicolin, bromo-deoxyuridine (BrdU), 5-azacytidine and distamycin A. Folate stress caused by methotrexate exposure also induces a group of rare fr ...
Prep1.1 has essential genetic functions in hindbrain development
Prep1.1 has essential genetic functions in hindbrain development

... Published by The Company of Biologists 2004 doi:10.1242/dev.00948 ...
B. Eukaryotic RNA polymerases
B. Eukaryotic RNA polymerases

... (2) Located 5 - 10 bases upstream of first codon (+1) transcribed (a) Located within -21 to -4, depending on the gene (3) This sequence orients RNA polymerase and is place of strand separation 6. There is also another conserved sequence further upstream a) -35 sequence (1) TTGACA (2) Mutations in t ...
Prof. Kamakaka`s Lecture 16 Notes
Prof. Kamakaka`s Lecture 16 Notes

Prep1.1 has essential genetic functions in hindbrain development
Prep1.1 has essential genetic functions in hindbrain development

... Published by The Company of Biologists 2004 doi:10.1242/dev.00948 ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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