Regulation of the S100B gene by α1-adrenergic - AJP
... of this adaptive response. Because adult cardiac myocytes are terminally differentiated and have lost the ability to divide, this increase in mass is due to enlargement of individual myocytes. The hypertrophic response can be reproduced in rat and mouse experimental models and cultured neonatal card ...
... of this adaptive response. Because adult cardiac myocytes are terminally differentiated and have lost the ability to divide, this increase in mass is due to enlargement of individual myocytes. The hypertrophic response can be reproduced in rat and mouse experimental models and cultured neonatal card ...
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... strikingly reminiscent of those of the corresponding Drosophila (e.g. Leptin et al. 1992; Nieto 2002) and vertebrate genes (e.g. Sefton et al. 1998). That an Acropora snail ortholog should be expressed in such a strikingly Drosophila-like pattern during a process that is strongly reminiscent of gast ...
... strikingly reminiscent of those of the corresponding Drosophila (e.g. Leptin et al. 1992; Nieto 2002) and vertebrate genes (e.g. Sefton et al. 1998). That an Acropora snail ortholog should be expressed in such a strikingly Drosophila-like pattern during a process that is strongly reminiscent of gast ...
Unexpected Complexity of Poly(A)-Binding Protein Gene Families in
... Manuscript received August 16, 2002 Accepted for publication October 9, 2002 ABSTRACT Eukaryotic poly(A)-binding protein (PABP) is a ubiquitous, essential factor involved in mRNA biogenesis, translation, and turnover. Most eukaryotes examined have only one or a few PABPs. In contrast, eight expresse ...
... Manuscript received August 16, 2002 Accepted for publication October 9, 2002 ABSTRACT Eukaryotic poly(A)-binding protein (PABP) is a ubiquitous, essential factor involved in mRNA biogenesis, translation, and turnover. Most eukaryotes examined have only one or a few PABPs. In contrast, eight expresse ...
Disruption of an N-acetyltransferase gene in the
... according to published literature (True, 2003; Wittkopp et al., 2003a; Arakane et al., 2009)] is illustrated in the center (see Discussion). (A)Adult wildtype (+/+) and mln mutant (mln/mln) Bombyx mori. (B)Regional pigmentation phenotypes of mln and wild-type larvae. In mln, the head and forelegs ...
... according to published literature (True, 2003; Wittkopp et al., 2003a; Arakane et al., 2009)] is illustrated in the center (see Discussion). (A)Adult wildtype (+/+) and mln mutant (mln/mln) Bombyx mori. (B)Regional pigmentation phenotypes of mln and wild-type larvae. In mln, the head and forelegs ...
Recurrent patterns of DNA copy number alterations in tumors reflect
... and more specifically that recurrent profiles at the level of PCA correlate with measured glycolytic phenotypes (FDGavidity in the tumor) as well as with increased proliferation. This primary PCA signature is also associated with p53 mutations, and hence may point towards a preponderance towards gen ...
... and more specifically that recurrent profiles at the level of PCA correlate with measured glycolytic phenotypes (FDGavidity in the tumor) as well as with increased proliferation. This primary PCA signature is also associated with p53 mutations, and hence may point towards a preponderance towards gen ...
Alu
... Place K points into the space represented by the objects that are being clustered. These points represent initial group centroids. Assign each object to the group that has the closest centroid. When all objects have been assigned, recalculate the positions of the K centroids. Repeat Steps 2 an ...
... Place K points into the space represented by the objects that are being clustered. These points represent initial group centroids. Assign each object to the group that has the closest centroid. When all objects have been assigned, recalculate the positions of the K centroids. Repeat Steps 2 an ...
D. melanogaster - GEP Community Server
... Retrieve the sequences of the initial exons from the Transcript Details tab of the Gene Record Finder Use placement of the flanking exons to reduce the size of the search region if possible Increase sensitivity of nucleotide searches Change Program Selection to blastn Change Word size to 7 Change Ma ...
... Retrieve the sequences of the initial exons from the Transcript Details tab of the Gene Record Finder Use placement of the flanking exons to reduce the size of the search region if possible Increase sensitivity of nucleotide searches Change Program Selection to blastn Change Word size to 7 Change Ma ...
Get PDF - Wiley Online Library
... 2009). We recently suggested that some aneuploid CNVs may be selected to balance the effects of mutations, epigenetic silencing, and other gene losses acquired during the continuous division of chromosomally unstable cancer cells (Bazeley et al., 2011). We now show evidence for increased mRNA levels ...
... 2009). We recently suggested that some aneuploid CNVs may be selected to balance the effects of mutations, epigenetic silencing, and other gene losses acquired during the continuous division of chromosomally unstable cancer cells (Bazeley et al., 2011). We now show evidence for increased mRNA levels ...
Testing the ABC floral-organ identity model: expression of
... Clone and sequence the ABC genes. Look for similarities with sequenced genes already in the database. ...
... Clone and sequence the ABC genes. Look for similarities with sequenced genes already in the database. ...
The molecular genetics of head development in Drosophila
... during evolution. In various species, segmental appendages are greatly reduced and apodemes and neuromeres difficult to discern. In addition to a metameric body plan, both arthropods and annelids have other similarities in general body structure. Both groups have dorsal hearts and related nervous sy ...
... during evolution. In various species, segmental appendages are greatly reduced and apodemes and neuromeres difficult to discern. In addition to a metameric body plan, both arthropods and annelids have other similarities in general body structure. Both groups have dorsal hearts and related nervous sy ...
Bayesian Partition Models for Identifying Expression Quantitative
... certain genes. By assaying gene expression and genetic variation (e.g., SNPs and/or copy number variations (CNVs)) simultaneously in segregating populations, scientists wish to correlate variations in the gene expression with genomic sequence variations. In such cases we say that a gene’s expression ...
... certain genes. By assaying gene expression and genetic variation (e.g., SNPs and/or copy number variations (CNVs)) simultaneously in segregating populations, scientists wish to correlate variations in the gene expression with genomic sequence variations. In such cases we say that a gene’s expression ...
Keverne et al (2001)
... Keverne, 1994; Brown et al., 1996). These transcription factors (Fos proteins or estradiol and its receptor complex) then activate the protein synthesis cascades required for the expression of maternal behavior. A similar role may be played by Peg3, presumably encoding a transcription factor and hig ...
... Keverne, 1994; Brown et al., 1996). These transcription factors (Fos proteins or estradiol and its receptor complex) then activate the protein synthesis cascades required for the expression of maternal behavior. A similar role may be played by Peg3, presumably encoding a transcription factor and hig ...
Analysis of DNA transcription termination sequences of gene coding
... whom the optimal hairpins have a stem-length of 4-8 base pairs or even more. Analysis of phaC1-phaZ intergenic region revealed that it contains from 52% to 73% GC nucleotides. Research into nucleotide content of the phaC1phaZ intergenic region showed that the GC pairs were from 52% to 73%. Recently ...
... whom the optimal hairpins have a stem-length of 4-8 base pairs or even more. Analysis of phaC1-phaZ intergenic region revealed that it contains from 52% to 73% GC nucleotides. Research into nucleotide content of the phaC1phaZ intergenic region showed that the GC pairs were from 52% to 73%. Recently ...
1 X chromosome crossover formation and genome stability in
... responding to DNA damage. Interestingly, a hypomorphic allele of the HAT mys1 completely rescued xnd-1 IR sensitivity, improved fecundity, and restored meiotic DSB kinetics. This allele also reduced H2AK5ac levels, suggesting these phenotypes may be a consequence of altered H2AK5ac levels. Although ...
... responding to DNA damage. Interestingly, a hypomorphic allele of the HAT mys1 completely rescued xnd-1 IR sensitivity, improved fecundity, and restored meiotic DSB kinetics. This allele also reduced H2AK5ac levels, suggesting these phenotypes may be a consequence of altered H2AK5ac levels. Although ...
Genetic determinants of sense organ identity in
... sense organs: the mono-innervated external sense organs (mes), the poly-innervated external sense organs (p-es) and the chordotonal internal sense organs (ch). The three types of organs differ in their lineage, morphology and neuronal connectivity, thereby providing a useful system to examine the ge ...
... sense organs: the mono-innervated external sense organs (mes), the poly-innervated external sense organs (p-es) and the chordotonal internal sense organs (ch). The three types of organs differ in their lineage, morphology and neuronal connectivity, thereby providing a useful system to examine the ge ...
The Effect of Chromosomal Position on the Expression of the
... the influence of flanking sequences on gene expression. The tissue distribution of XDH activity in all the strains was normal. Each line exhibited a characteristic level of adult XDH-specific activity. The majority of these values were close to wild-type levels; however, the total variation in speci ...
... the influence of flanking sequences on gene expression. The tissue distribution of XDH activity in all the strains was normal. Each line exhibited a characteristic level of adult XDH-specific activity. The majority of these values were close to wild-type levels; however, the total variation in speci ...
Mendelian and Non-Mendelian Regulation of Gene Expression in
... between the population and the parents. We first focused on the expression levels of 22,242 genes that were detected in both parents and at least 90% of the IBM RILs. The mean expression levels in the RILs were similar to the mid-parent values for most genes (Figure 1B). Transgressive segregation, d ...
... between the population and the parents. We first focused on the expression levels of 22,242 genes that were detected in both parents and at least 90% of the IBM RILs. The mean expression levels in the RILs were similar to the mid-parent values for most genes (Figure 1B). Transgressive segregation, d ...
The amphioxus hairy family: differential fate after duplication.
... but in contrast to its paralog, neither in segmented somites nor in the PSM. Within the CNS, her9 is predominantly expressed in the fore- and midbrain, and transiently in the hindbrain, leaving a non-expressing gap at the midbrain-hindbrain boundary (MHB), and it is also expressed in the midline mes ...
... but in contrast to its paralog, neither in segmented somites nor in the PSM. Within the CNS, her9 is predominantly expressed in the fore- and midbrain, and transiently in the hindbrain, leaving a non-expressing gap at the midbrain-hindbrain boundary (MHB), and it is also expressed in the midline mes ...
Synthetic Chemical Inducers and Genetic
... induction of PrhaBAD resulted from poor rhaS expression, which in turn was due to suboptimum interaction of candidate inducers with RhaR. A new reporter plasmid, pCK302, was thus constructed that expresses the MG1655 rhaS gene constitutively (rhaS+), insulating it from the native rhaSR regulatory ca ...
... induction of PrhaBAD resulted from poor rhaS expression, which in turn was due to suboptimum interaction of candidate inducers with RhaR. A new reporter plasmid, pCK302, was thus constructed that expresses the MG1655 rhaS gene constitutively (rhaS+), insulating it from the native rhaSR regulatory ca ...
Multiple Testing Corrections
... Multiple testing corrections adjust p-values derived from multiple statistical tests to correct for occurrence of false positives. In microarray data analysis, false positives are genes that are found to be statistically different between conditions, but are not in reality. B. Importance of Multiple ...
... Multiple testing corrections adjust p-values derived from multiple statistical tests to correct for occurrence of false positives. In microarray data analysis, false positives are genes that are found to be statistically different between conditions, but are not in reality. B. Importance of Multiple ...
Involvement of Pax6 and Otx2 in the forebrain
... Received for publication 29 January 2004, accepted 29 January 2004 ...
... Received for publication 29 January 2004, accepted 29 January 2004 ...