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... Prevent their associated proteins from being produced • histone acetylation • methylation • small RNA interference Sexual reproduction has been suggested to play a role in reducing the number of deleterious transposable elements ...
... Prevent their associated proteins from being produced • histone acetylation • methylation • small RNA interference Sexual reproduction has been suggested to play a role in reducing the number of deleterious transposable elements ...
The Toll immune-regulated Drosophila protein Fondue is involved in
... induced upon microbial infection (De Gregorio et al., 2002). Prior to this humoral response, coagulation acts to seal wounds and to trap microbes, blocking their entry into the hemocoel. In Drosophila larvae, a clot composed of fibers trapping hemocytes is rapidly generated at the site of injury. It ...
... induced upon microbial infection (De Gregorio et al., 2002). Prior to this humoral response, coagulation acts to seal wounds and to trap microbes, blocking their entry into the hemocoel. In Drosophila larvae, a clot composed of fibers trapping hemocytes is rapidly generated at the site of injury. It ...
cis-Regulatory Elements and trans-Acting Factors
... promoter to direct CAT expression.'7'18 There is a single recent study on a trans-acting factor controlling human renin gene expression showing that nuclear extracts isolated from a rat lactotrope precursor cell line (GC) interact with a pituitary-specific factor (Pit-1) binding site consensus seque ...
... promoter to direct CAT expression.'7'18 There is a single recent study on a trans-acting factor controlling human renin gene expression showing that nuclear extracts isolated from a rat lactotrope precursor cell line (GC) interact with a pituitary-specific factor (Pit-1) binding site consensus seque ...
Expression of Allene Oxide Synthase Determines - Bio
... Southern analysis of tomato genomic DNA indicated the existence of a single gene encoding AOS (Fig. 2a). Restriction with BamHI revealed only a single band, while that with either HindIII or EcoRI yielded two or three bands in concurrence with the presence of internal restriction sites for these enz ...
... Southern analysis of tomato genomic DNA indicated the existence of a single gene encoding AOS (Fig. 2a). Restriction with BamHI revealed only a single band, while that with either HindIII or EcoRI yielded two or three bands in concurrence with the presence of internal restriction sites for these enz ...
Identification of chromosome intervals from 129 and C57BL/6 mouse
... murine physiology. There is, however, accumulating evidence that genetic factors other than the actual disrupted gene can influence the resulting phenotype of the knockout mouse. In this regard, it is of note that the majority of the gene-targeted strains are initially developed on a hybrid genetic ...
... murine physiology. There is, however, accumulating evidence that genetic factors other than the actual disrupted gene can influence the resulting phenotype of the knockout mouse. In this regard, it is of note that the majority of the gene-targeted strains are initially developed on a hybrid genetic ...
Article Why There Are No Essential Genes on
... are differences between functions coded for by mobile genes and those in the “core” genome and that these differences can be seen between plasmids and chromosomes. In particular, it has been suggested that essential genes, such as those involved in the formation of structural proteins or in basic me ...
... are differences between functions coded for by mobile genes and those in the “core” genome and that these differences can be seen between plasmids and chromosomes. In particular, it has been suggested that essential genes, such as those involved in the formation of structural proteins or in basic me ...
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... RNA synthesis in embryos described previously (Kafiani & Timofeeva, 1964, 1965). The relative rate of dRNA synthesis ('dRNA-synthesizing activity') was estimated at different stages of development in normal embryos of loach (Misgumusfossilis) and in embryos partially or nearly wholly deprived of nuc ...
... RNA synthesis in embryos described previously (Kafiani & Timofeeva, 1964, 1965). The relative rate of dRNA synthesis ('dRNA-synthesizing activity') was estimated at different stages of development in normal embryos of loach (Misgumusfossilis) and in embryos partially or nearly wholly deprived of nuc ...
Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1a/tcf1
... conserved DNA binding domain including POU-like domain and atypical homeodomain with 21 amino acid (a.a.) loop between helix 2 and helix 3, but variant transactivation domain (Fig. 1). Zebrafish hnf1a is most similar to salmon hnf1 closer to tetrapodian hnf1a than to hnf1b. Compared with other verte ...
... conserved DNA binding domain including POU-like domain and atypical homeodomain with 21 amino acid (a.a.) loop between helix 2 and helix 3, but variant transactivation domain (Fig. 1). Zebrafish hnf1a is most similar to salmon hnf1 closer to tetrapodian hnf1a than to hnf1b. Compared with other verte ...
Supporting Information Parfenov et al. 10.1073/pnas.1416074111
... P values (adjusted by the Benjamini–Hochberg procedure) less than 0.05 were considered as significantly differentially methylated or expressed. The sites and corresponding statistics for all CpG loci and genes can be found in Dataset S1, Tables S3 and S4. Additionally, we carried out an unsupervised ...
... P values (adjusted by the Benjamini–Hochberg procedure) less than 0.05 were considered as significantly differentially methylated or expressed. The sites and corresponding statistics for all CpG loci and genes can be found in Dataset S1, Tables S3 and S4. Additionally, we carried out an unsupervised ...
Jigsaw handout - the Biology Scholars Program Wiki
... binds to lac repressor and causes a conformation change that alters the structure of lac repressor so that it cannot bind to DNA. Therefore, in the presence of lactose, lac repressor does not bind to the operator and RNA polymerase can transcribe the genes in the lac operon. Case study (homework or ...
... binds to lac repressor and causes a conformation change that alters the structure of lac repressor so that it cannot bind to DNA. Therefore, in the presence of lactose, lac repressor does not bind to the operator and RNA polymerase can transcribe the genes in the lac operon. Case study (homework or ...
Structure-Function Analysis of the Conserved Histone Chaperone
... Chromatin structure is crucial to regulate access to the genome for processes such as transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin struct ...
... Chromatin structure is crucial to regulate access to the genome for processes such as transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin struct ...
Chapter 3 Clustering Microarray Data
... then gene clusters should be based on all the samples, but it may be more appropriate to use a clustering method that is designed for clustering time series, which clusters genes on the basis of key features of their expression profiles. Assumptions of conventional clustering methods such as those d ...
... then gene clusters should be based on all the samples, but it may be more appropriate to use a clustering method that is designed for clustering time series, which clusters genes on the basis of key features of their expression profiles. Assumptions of conventional clustering methods such as those d ...
Functions of DNA methylation: islands, start sites, gene bodies and
... and are marked with trimethylation of histone H3 at lysine 4 (H3K4me3)30 (FIG. 1). The levels of gene expression are controlled by transcription factors31. CGI promoters can be repressed by various mechanisms, such as repression mediated by Polycomb proteins. For example, genes encoding master regul ...
... and are marked with trimethylation of histone H3 at lysine 4 (H3K4me3)30 (FIG. 1). The levels of gene expression are controlled by transcription factors31. CGI promoters can be repressed by various mechanisms, such as repression mediated by Polycomb proteins. For example, genes encoding master regul ...
Bridging the transgenerational gap with epigenetic memory
... in mammals during the 1980s provided the first indication that epigenetic modifications, such as DNA methylation, were not entirely erased between generations and could underlie transgenerational epigenetic inheritance [6–11]. It was also around this time that several cases of transgenerational epig ...
... in mammals during the 1980s provided the first indication that epigenetic modifications, such as DNA methylation, were not entirely erased between generations and could underlie transgenerational epigenetic inheritance [6–11]. It was also around this time that several cases of transgenerational epig ...
nar-02451-data-e-201
... include names/symbols of genes, diseases, methylation words, species, evidence sentences that include the association, PubMed Central ID of the article where the sentence is mentioned, PubMed ID of the abstract where the association is mentioned, and a confidence score generated by DEMGD system. The ...
... include names/symbols of genes, diseases, methylation words, species, evidence sentences that include the association, PubMed Central ID of the article where the sentence is mentioned, PubMed ID of the abstract where the association is mentioned, and a confidence score generated by DEMGD system. The ...
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... H3K27me3 mark targets both, genes and repetitive elements and is anti-correlated with transcriptional activity. We show that H3K27me3 distribution over its targets is not uniform, but can be grouped into several different clusters that correlate with different levels of repression. Furthermore, we d ...
... H3K27me3 mark targets both, genes and repetitive elements and is anti-correlated with transcriptional activity. We show that H3K27me3 distribution over its targets is not uniform, but can be grouped into several different clusters that correlate with different levels of repression. Furthermore, we d ...
Agilent Whole Human Genome Oligo Microarray Kit
... Optimizing probes for stellar performance Figures A & B depict Agilent’s proven process for ‘superclustering’ and choosing multiple probes within a GeneBin (gene and associated transcripts). In many cases, more than one consensus region will be selected for a given GeneBin. Figure A demonstrates the ...
... Optimizing probes for stellar performance Figures A & B depict Agilent’s proven process for ‘superclustering’ and choosing multiple probes within a GeneBin (gene and associated transcripts). In many cases, more than one consensus region will be selected for a given GeneBin. Figure A demonstrates the ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... Bacillus subtilis possesses interlinked routes for the synthesis of proline. The ProJ–ProA–ProH route is responsible for the production of proline as an osmoprotectant, and the ProB–ProA–ProI route provides proline for protein synthesis. We show here that the transcription of the anabolic proBA and ...
... Bacillus subtilis possesses interlinked routes for the synthesis of proline. The ProJ–ProA–ProH route is responsible for the production of proline as an osmoprotectant, and the ProB–ProA–ProI route provides proline for protein synthesis. We show here that the transcription of the anabolic proBA and ...
REVIEW ARTICLE Gene cassettes
... Gene cassettes form a diverse group of small mobile elements that already includes over 40 members. Usually, each cassette contains only a single gene and a specific recombination site. At present, the genes found in cassettes are mostly antibiotic-resistance genes, but it is likely that gene casset ...
... Gene cassettes form a diverse group of small mobile elements that already includes over 40 members. Usually, each cassette contains only a single gene and a specific recombination site. At present, the genes found in cassettes are mostly antibiotic-resistance genes, but it is likely that gene casset ...
Conservation of Brachyury (T) genes in amphioxus and vertebrates
... because these are the only invertebrate animals to possess a notochord. Yasuo and Satoh (1993, 1994) reported the cloning of a Brachyury homologue (As-T) from the ascidian tunicate Halocynthia roretzi. Their precise description of As-T expression, at the single cell level, revealed a significant dif ...
... because these are the only invertebrate animals to possess a notochord. Yasuo and Satoh (1993, 1994) reported the cloning of a Brachyury homologue (As-T) from the ascidian tunicate Halocynthia roretzi. Their precise description of As-T expression, at the single cell level, revealed a significant dif ...
Journal Club Pack - Circulation Research
... although we have previously shown that phenotypic switching of cultured SMC is dependent on Krupplelike factor (KLF)4. Objective: The goals of the present studies were to ascertain if (1) injury-induced repression of SM22α gene after vascular injury is mediated through KLF4 binding to the G/C Repres ...
... although we have previously shown that phenotypic switching of cultured SMC is dependent on Krupplelike factor (KLF)4. Objective: The goals of the present studies were to ascertain if (1) injury-induced repression of SM22α gene after vascular injury is mediated through KLF4 binding to the G/C Repres ...
A Conserved Molecular Framework for Compound Leaf Development
... search tree) from this multiple sequence alignment were generated with PhyML(2) using optimal amino acide substitution model JTT + G select using ModelGenerator (v0.84)(3). The NAC1 protein from A. thaliana was used as outgroup. Bootstrap confidence values were obtained by 100 replicates and only bo ...
... search tree) from this multiple sequence alignment were generated with PhyML(2) using optimal amino acide substitution model JTT + G select using ModelGenerator (v0.84)(3). The NAC1 protein from A. thaliana was used as outgroup. Bootstrap confidence values were obtained by 100 replicates and only bo ...