RNA Structure, Function, and Synthesis RNA - Rose
... contrast, RNA polymerase II, which generates the mRNA used for protein synthesis, is heavily regulated. Multicellular organisms need an additional level of control – different cell types, which all contain the same genome, need to express different genes even under the same conditions. This is achie ...
... contrast, RNA polymerase II, which generates the mRNA used for protein synthesis, is heavily regulated. Multicellular organisms need an additional level of control – different cell types, which all contain the same genome, need to express different genes even under the same conditions. This is achie ...
Microarrays
... Identify groups of possibly co-regulated genes (e.g. so you can look for common sequence motifs) ...
... Identify groups of possibly co-regulated genes (e.g. so you can look for common sequence motifs) ...
Elongation and Termination of Transcription
... – In Drosophila, the RNA polymerase can pause after synthesizing ~ 25 nucleotides of RNA in many genes. – under elevated temperature conditions, the heat shock factor stimulates elongation by release from pausing. – Other possible examples: mammalian c-myc, HIV LTR • This is in addition to regulatio ...
... – In Drosophila, the RNA polymerase can pause after synthesizing ~ 25 nucleotides of RNA in many genes. – under elevated temperature conditions, the heat shock factor stimulates elongation by release from pausing. – Other possible examples: mammalian c-myc, HIV LTR • This is in addition to regulatio ...
BIO 208 Homework: Bacterial Genetics 2011 17.1 constitutive gene
... 17.1 constitutive gene expression – certain genes are always “on” because the gene products (proteins) are required by the cell all of the time. Regulated gene expression for gene active in response to cellular needs. 17.3 polycistronic mRNA – coding information from more than one gene on one mRNA m ...
... 17.1 constitutive gene expression – certain genes are always “on” because the gene products (proteins) are required by the cell all of the time. Regulated gene expression for gene active in response to cellular needs. 17.3 polycistronic mRNA – coding information from more than one gene on one mRNA m ...
Molecular Cell Biology - Biomedical Informatics
... proteins, whose presence on the DNA affects the rate of transcription initiation. These sequences can be located adjacent to the promoter, far upstream of it, or even downstream of the gene. DNA looping is thought to allow gene regulatory proteins bound at any of these positions to interact with the ...
... proteins, whose presence on the DNA affects the rate of transcription initiation. These sequences can be located adjacent to the promoter, far upstream of it, or even downstream of the gene. DNA looping is thought to allow gene regulatory proteins bound at any of these positions to interact with the ...
Chapter 8
... that are partially double-helical. The pri-miRNA is processed to a shorter ~ 70 nt pre-miRNA that is then transported to the cytoplasm. The pre-miRNA, which folds into a hairpin structure, is bound by a protein complex containing the enzyme known as Dicer. Dicer cleaves the molecule producing a 21-2 ...
... that are partially double-helical. The pri-miRNA is processed to a shorter ~ 70 nt pre-miRNA that is then transported to the cytoplasm. The pre-miRNA, which folds into a hairpin structure, is bound by a protein complex containing the enzyme known as Dicer. Dicer cleaves the molecule producing a 21-2 ...
1 Biological information flow
... Cis-acting element : DNA sequences that regulate expression of gene located on same DNA molecule Inr: initiator element ...
... Cis-acting element : DNA sequences that regulate expression of gene located on same DNA molecule Inr: initiator element ...
Down Syndrome: Antonarakis et al. (2004)
... We might consider that there are two categories of genes on human chromosome 21 (HSA21); those that are dosage sensitive (that is, three copies result in phenotypic effects; shown in red) and contribute to the phenotypes of Down syndrome (DS), and those that are not dosage sensitive (green) and ther ...
... We might consider that there are two categories of genes on human chromosome 21 (HSA21); those that are dosage sensitive (that is, three copies result in phenotypic effects; shown in red) and contribute to the phenotypes of Down syndrome (DS), and those that are not dosage sensitive (green) and ther ...
Gene Section NUP98 (nucleoporin 98 kDa) Atlas of Genetics and Cytogenetics
... Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet. 1996 Feb;12(2):154-8 ...
... Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet. 1996 Feb;12(2):154-8 ...
Improving coverage of poorly sequenced regions in clinical exomes
... We have previously reported an orthogonal sequencing approach for clinical whole exome sequencing in which results of two next-generation sequencing platforms are combined for rapid variant confirmation. This both reduces the Sanger sequencing confirmation burden by ~95% and increases overall assay ...
... We have previously reported an orthogonal sequencing approach for clinical whole exome sequencing in which results of two next-generation sequencing platforms are combined for rapid variant confirmation. This both reduces the Sanger sequencing confirmation burden by ~95% and increases overall assay ...
rabbit - Ensembl Mobile Site
... Addition of UTR to coding models Approximate time: 1 week The set of coding models was extended into the untranslated regions (UTRs) using rabbit cDNA and EST sequences. This resulted in 4,121 (of 6,347) rabbit coding models with UTR, 1,693 (of 10,029) human coding models with UTR, 1,601(of 8,833) m ...
... Addition of UTR to coding models Approximate time: 1 week The set of coding models was extended into the untranslated regions (UTRs) using rabbit cDNA and EST sequences. This resulted in 4,121 (of 6,347) rabbit coding models with UTR, 1,693 (of 10,029) human coding models with UTR, 1,601(of 8,833) m ...
The role of epigenetics in the regulation of gene transcription
... ♦ Extent of methylation in the regulatory region of the DNA governing the expression of the agouti gene (responsible for the yellow coat colour) was analysed in the offspring ♦Y2 offspring: Mothers fed a diet high in methyl supplements, responsible for high degree of methylation in the regulatory re ...
... ♦ Extent of methylation in the regulatory region of the DNA governing the expression of the agouti gene (responsible for the yellow coat colour) was analysed in the offspring ♦Y2 offspring: Mothers fed a diet high in methyl supplements, responsible for high degree of methylation in the regulatory re ...
Kein Folientitel
... 2) The cytochrome P450 family is very important for toxicological microarray analysis since most isoforms repond to different toxic compounds. Is it possible to design a cDNA fragment (minimal size 200 bp) that would be able to separate CYP2A6 and CYP2A7? What is the situation with CYP1A1 and CYP1A2 ...
... 2) The cytochrome P450 family is very important for toxicological microarray analysis since most isoforms repond to different toxic compounds. Is it possible to design a cDNA fragment (minimal size 200 bp) that would be able to separate CYP2A6 and CYP2A7? What is the situation with CYP1A1 and CYP1A2 ...
ProdoNet: identification and visualization of prokaryotic gene
... For the functional exploration of a particular gene of the network, a gene context menu provides the full name of the corresponding protein and links to the PRODORIC and UniProtKB databases. In case of a gene coding for an enzyme, the menu offers the ‘metabolic pathways’ option, leading to a table th ...
... For the functional exploration of a particular gene of the network, a gene context menu provides the full name of the corresponding protein and links to the PRODORIC and UniProtKB databases. In case of a gene coding for an enzyme, the menu offers the ‘metabolic pathways’ option, leading to a table th ...
Basics for Bioinformatics
... the concept of a gene as the fragments of the DNA sequence that finally produce some protein products. This is still true in many contexts today. More strictly, these DNA segments should be called protein-coding genes, as scientists have found that there are some or many other parts on the genome th ...
... the concept of a gene as the fragments of the DNA sequence that finally produce some protein products. This is still true in many contexts today. More strictly, these DNA segments should be called protein-coding genes, as scientists have found that there are some or many other parts on the genome th ...
Transcription - Faculty Web Pages
... • How does this affect the timing and regulation of protein synthesis in a bacterial cell vs. a eukaryotic cell? • How is a gene defined? (Mendelian definition and more modern definition) • Must all genes encode a protein? • What are the different classes of RNA and their functions? • If an mRNA is ...
... • How does this affect the timing and regulation of protein synthesis in a bacterial cell vs. a eukaryotic cell? • How is a gene defined? (Mendelian definition and more modern definition) • Must all genes encode a protein? • What are the different classes of RNA and their functions? • If an mRNA is ...
Gene Concept - Govt. College Aron
... unit, but the gene cluster is usually transmitted from one generation to the next as a single unit. Thus, the units of transmission and transcription are not always the same. Likewise, the histone genes have been observed to be repeated in such tandem repeats in many higher eukaryotic organisms ...
... unit, but the gene cluster is usually transmitted from one generation to the next as a single unit. Thus, the units of transmission and transcription are not always the same. Likewise, the histone genes have been observed to be repeated in such tandem repeats in many higher eukaryotic organisms ...
