Leukaemia Section t(10;17)(p15;q21) ZMYND11/MBTD1 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... which are known to maintain the transcriptionally repressive state of genes, probably via chromatin remodeling (Nady et al., 2012). ...
... which are known to maintain the transcriptionally repressive state of genes, probably via chromatin remodeling (Nady et al., 2012). ...
Epigenetics
... What does “Epigenetics” mean? • gene expression changes not caused by changes in DNA sequence ...
... What does “Epigenetics” mean? • gene expression changes not caused by changes in DNA sequence ...
HNF-1B specifically regulates the transcription of the
... consists of seven exons spanning 9.2 kb of genomic DNA [15]. Three transcripts are associated to this gene, with FXYD2a (NM001680) and FXYD2b (NM021603) being the main ones. Promoter elements were identified around the alternative start sites for exon-b and exon-a, that encode different N-termini of ...
... consists of seven exons spanning 9.2 kb of genomic DNA [15]. Three transcripts are associated to this gene, with FXYD2a (NM001680) and FXYD2b (NM021603) being the main ones. Promoter elements were identified around the alternative start sites for exon-b and exon-a, that encode different N-termini of ...
supplement 3 - Springer Static Content Server
... (in more detail, red genes are well separated from blue genes in Figure 1(a), but both are mixed together with genes of other colors). The failure of PCA to classify the differentially expressed genes, even when exhausting all principal components, may be attributed to the unbalance of the gene set, ...
... (in more detail, red genes are well separated from blue genes in Figure 1(a), but both are mixed together with genes of other colors). The failure of PCA to classify the differentially expressed genes, even when exhausting all principal components, may be attributed to the unbalance of the gene set, ...
제3회 한국분자세포생물학회 이동성 유전인자분과 학술대회
... In eukaryotes genome, activity of transposable elements is suppressed by DNA methylation in several regions such as promoter, enhancer, and regulatory region. However, in tumor cells, some alternative transcripts including transposable elements are overexpressed because methylation of transposable e ...
... In eukaryotes genome, activity of transposable elements is suppressed by DNA methylation in several regions such as promoter, enhancer, and regulatory region. However, in tumor cells, some alternative transcripts including transposable elements are overexpressed because methylation of transposable e ...
Gene regulation in biological responses
... • How long does it last? • How much dsRNA is required? ...
... • How long does it last? • How much dsRNA is required? ...
Leukaemia Section t(3;11)(q26;p15) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differsntiation. ...
... likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differsntiation. ...
NONRANDOM GENE DISTRIBUTION ON HUMAN CHROMOSOMES
... Human chromosomes are heterogeneous in structure and function. This is the reason for specific banding patterns produced by various chromosome staining techniques. The human genome is a mosaic of isochors and can be partitioned into five families, L1, L2, H1, H2 and H3, characterized by increasing G ...
... Human chromosomes are heterogeneous in structure and function. This is the reason for specific banding patterns produced by various chromosome staining techniques. The human genome is a mosaic of isochors and can be partitioned into five families, L1, L2, H1, H2 and H3, characterized by increasing G ...
Prok and Euk Gene Expression
... CAP [S17] a. This is a schematic showing CAP and cAMP bound to an allosteric site b. Binding causes change in the protein i. Allows it to bind to upstream promoter sequence ii. When it binds, it actually bends DNA XVIII. CAP Activation of RNA Polymerase [S18] a. Bending of DNA allows it to interact ...
... CAP [S17] a. This is a schematic showing CAP and cAMP bound to an allosteric site b. Binding causes change in the protein i. Allows it to bind to upstream promoter sequence ii. When it binds, it actually bends DNA XVIII. CAP Activation of RNA Polymerase [S18] a. Bending of DNA allows it to interact ...
Significance analysis of microarrays (SAM)
... • SAM gives estimates of the False Discovery Rate (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. • It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) ...
... • SAM gives estimates of the False Discovery Rate (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. • It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) ...
SEPA: Single-Cell Gene Expression Pattern Analysis
... ordering concept provides a novel method of exploring single-cell RNA-seq data. If one has available true experimental time or pseudo temporal cell ordering information, a natural question to ask is what expression patterns do these genes have along the true or pseudo time axis. The expression patte ...
... ordering concept provides a novel method of exploring single-cell RNA-seq data. If one has available true experimental time or pseudo temporal cell ordering information, a natural question to ask is what expression patterns do these genes have along the true or pseudo time axis. The expression patte ...
Assessing the gene content of the megagenome : sugar pine (Pinus
... roots, with GO terms associated with genes involved in stress response, including DnaJ-like chaperone proteins, transcripts related to the glutathione and ubiquitin pathways, calciumtransporting ATPases, and ethylene-responsive transcription factors. Abiotic stresses, such as drought, salt and freez ...
... roots, with GO terms associated with genes involved in stress response, including DnaJ-like chaperone proteins, transcripts related to the glutathione and ubiquitin pathways, calciumtransporting ATPases, and ethylene-responsive transcription factors. Abiotic stresses, such as drought, salt and freez ...
Genomics
... Fig. 1. Structure of six AtUGT85A genes and three AtGUS genes in Arabidopsis. (A) Structure of AtUGT85A1, 2, 3, 4, 6, and 7 on chromosome 1. Five AtUGT85A genes are clustered together in an 18-kb region on the left arm of chromosome 1. AtUGT85A4 is located at the end of left arm of chromosome 1. Ope ...
... Fig. 1. Structure of six AtUGT85A genes and three AtGUS genes in Arabidopsis. (A) Structure of AtUGT85A1, 2, 3, 4, 6, and 7 on chromosome 1. Five AtUGT85A genes are clustered together in an 18-kb region on the left arm of chromosome 1. AtUGT85A4 is located at the end of left arm of chromosome 1. Ope ...
Text S2: Pre-processing Steps Applied to the Stem Cell Gene
... Gene expression datasets. The ESCs and iPSCs from the Bock data set can be accessed via GEO under the accession number GSE25970, and the Yan data set is stored under GSE36552. Initial pre-processing steps. All data was log2-transformed and normalized. For all data sets, a quality filter was applied ...
... Gene expression datasets. The ESCs and iPSCs from the Bock data set can be accessed via GEO under the accession number GSE25970, and the Yan data set is stored under GSE36552. Initial pre-processing steps. All data was log2-transformed and normalized. For all data sets, a quality filter was applied ...
BioMart: The linked dataset
... Data mining in Ensembl with BioMart Worked Example – Demonstrating the Linked Dataset BioMart can federate (join together) databases, in this example we will join two different datasets, Ensembl genes and RGD (the Rat Genome Database) to identify all Ensembl genes involved in carbohydrate metabolism ...
... Data mining in Ensembl with BioMart Worked Example – Demonstrating the Linked Dataset BioMart can federate (join together) databases, in this example we will join two different datasets, Ensembl genes and RGD (the Rat Genome Database) to identify all Ensembl genes involved in carbohydrate metabolism ...
Next-Generation Sequencing Applications Complement
... tumor. Abnormal gene expression of tumor-related genes can result from mutations in the coding region, mutations in the regulatory regions, aberrations in the spliceosome factors, or by epigenetic alterations. Sometimes, using RNA sequencing as an early method of analysis can directly confirm the me ...
... tumor. Abnormal gene expression of tumor-related genes can result from mutations in the coding region, mutations in the regulatory regions, aberrations in the spliceosome factors, or by epigenetic alterations. Sometimes, using RNA sequencing as an early method of analysis can directly confirm the me ...
Lecture 2. Hormone formation
... There are factors that determine a) if a cell is capable of producing a certain protein or not and b) if it is capable of producing that protein then how much will be produced (i.e., a cell can change the expression of its genes in response to various stimuli) The synthesis of all hormones requires ...
... There are factors that determine a) if a cell is capable of producing a certain protein or not and b) if it is capable of producing that protein then how much will be produced (i.e., a cell can change the expression of its genes in response to various stimuli) The synthesis of all hormones requires ...
The Humanized Fly - Barbara J. Culliton
... Flies age and die, faster than human beings, to be sure, but their aging appears to be under the control of similar genes. (Drosophila’s prodigious reproduction, coupled with their short life span is what makes them ideal or "model organisms" for laboratory research.) Flies have genes for apoptos ...
... Flies age and die, faster than human beings, to be sure, but their aging appears to be under the control of similar genes. (Drosophila’s prodigious reproduction, coupled with their short life span is what makes them ideal or "model organisms" for laboratory research.) Flies have genes for apoptos ...
Nature Rev.Mol.Cell Biol
... DNA bending can affect transcription and site-specific recombination ...
... DNA bending can affect transcription and site-specific recombination ...
