Genetics and genomics
... • Gene expression patterns can add to what we know about structure and function of the human body • Identifying which genes are active and inactive in particular cell types, under particular conditions, can add to our understanding of physiology • Gene expression monitors the proteins that a cell pr ...
... • Gene expression patterns can add to what we know about structure and function of the human body • Identifying which genes are active and inactive in particular cell types, under particular conditions, can add to our understanding of physiology • Gene expression monitors the proteins that a cell pr ...
Normalization of gene expression measurements in tumor tissues
... urothelial cell carcinomas:14,15 two pTa grade 1, two pTa grade 2, two pT1 grade 2, two pT2 grade 3, two pT3 grade 3, and two pT4 grade 3 with distant metastates. Total RNA was isolated from tissues and reverse transcribed to cDNA as described previously.16 ...
... urothelial cell carcinomas:14,15 two pTa grade 1, two pTa grade 2, two pT1 grade 2, two pT2 grade 3, two pT3 grade 3, and two pT4 grade 3 with distant metastates. Total RNA was isolated from tissues and reverse transcribed to cDNA as described previously.16 ...
KEY Exam 2 ID
... 60. Describe the control of the cell cycle before and after the mid-blastula transition in sea urchin embryos. Mitosis is stimulated by MPF (mitosis promoting factor), which consists of cdc2 (cyclin-dependent kinase) and its activator, cyclin B. Active MPF phosphorylates nuclear components that are ...
... 60. Describe the control of the cell cycle before and after the mid-blastula transition in sea urchin embryos. Mitosis is stimulated by MPF (mitosis promoting factor), which consists of cdc2 (cyclin-dependent kinase) and its activator, cyclin B. Active MPF phosphorylates nuclear components that are ...
Gene Section TSPY1 (testis specific protein, Y-linked 1) in Oncology and Haematology
... the relevance of TSPY's ability to stimulate the kinase activity of an activated cyclin B1/cdk complex in transiently transfected human HEK293 cells to its in vivo function within the testis is still unclear. - Kido and Lau (2008) have identified the eucaryotic elongation factor 1 alpha (eEF1A) in a ...
... the relevance of TSPY's ability to stimulate the kinase activity of an activated cyclin B1/cdk complex in transiently transfected human HEK293 cells to its in vivo function within the testis is still unclear. - Kido and Lau (2008) have identified the eucaryotic elongation factor 1 alpha (eEF1A) in a ...
10 gene expression: transcription
... 55 and 80 bases downstream of the transcription initiation point and within the gene. Please refer to figure 10.21. 14. As a result of posttranscriptional modifications, the mature eukaryotic mRNA has features lacking in the primary transcript: (1) 5'-CAP (a 7-methyl guanosine added in the “wrong” d ...
... 55 and 80 bases downstream of the transcription initiation point and within the gene. Please refer to figure 10.21. 14. As a result of posttranscriptional modifications, the mature eukaryotic mRNA has features lacking in the primary transcript: (1) 5'-CAP (a 7-methyl guanosine added in the “wrong” d ...
B Supplementary Figure 2
... flowering genes in the ZCE1 RNAi lines. Quantitative RT-PCR analysis shows the transcript levels of FLK (A) and FLC (B) upon cis-CA and trans-CA treatment, respectively. FLK is a positive regulator of flowering via suppressing the expression of another flowering gene FLC, while the role of FLC is to ...
... flowering genes in the ZCE1 RNAi lines. Quantitative RT-PCR analysis shows the transcript levels of FLK (A) and FLC (B) upon cis-CA and trans-CA treatment, respectively. FLK is a positive regulator of flowering via suppressing the expression of another flowering gene FLC, while the role of FLC is to ...
Chapter 13 Lecture Notes: DNA Function I. Transcription (General
... a) Can bind to specific DNA sequences and help RNA polymerase initiate transcription via protein-protein interactions or by altering the structure of the DNA. b) Transcription of some promoters requires an accessory transcriptional activator; at other promoters, the activators just increase the rate ...
... a) Can bind to specific DNA sequences and help RNA polymerase initiate transcription via protein-protein interactions or by altering the structure of the DNA. b) Transcription of some promoters requires an accessory transcriptional activator; at other promoters, the activators just increase the rate ...
Educational Items Section Hemoglobin genes; Sickle-cell anemia - Thalassemias
... way that it is not coding for any protein.- Chromosome 16: localization in 16p13.3. More recent duplication of the α1 and α2 genes; homology: they have close nucleotide sequences and an identical coding sequence. The θ gene is weakly express. Each gene is made of 3 exons (coding sequences) separate ...
... way that it is not coding for any protein.- Chromosome 16: localization in 16p13.3. More recent duplication of the α1 and α2 genes; homology: they have close nucleotide sequences and an identical coding sequence. The θ gene is weakly express. Each gene is made of 3 exons (coding sequences) separate ...
Lecture 7 - Crop, Soil, and Environmental Sciences | University of
... Several properties of the cauliflower mosaic virus (CaMV) indicate that it could provide a useful vector for gene transfer in higher plants: (1) it has a relatively small double-stranded genome that can be easily manipulated in vitro; (2) cloned viral DNA is infectious when rubbed onto healthy leave ...
... Several properties of the cauliflower mosaic virus (CaMV) indicate that it could provide a useful vector for gene transfer in higher plants: (1) it has a relatively small double-stranded genome that can be easily manipulated in vitro; (2) cloned viral DNA is infectious when rubbed onto healthy leave ...
How Is Gene Expression Regulated in Prokaryotes? 1. Regarding
... How Is Gene Expression Regulated in Prokaryotes? 1. Regarding the operons of prokaryotes: Draw an operon and label the promoter, operator, and genes that code for enzymes. ...
... How Is Gene Expression Regulated in Prokaryotes? 1. Regarding the operons of prokaryotes: Draw an operon and label the promoter, operator, and genes that code for enzymes. ...
Strategies for generating marker-free transgenic banana plants
... Abstract Bananas and plantains are an important source of food and income for millions of persons in the world. Their production is constrained by many biotic and abiotic stress factors but their improvement through traditional plant breeding methods is very difficult because they do not produce see ...
... Abstract Bananas and plantains are an important source of food and income for millions of persons in the world. Their production is constrained by many biotic and abiotic stress factors but their improvement through traditional plant breeding methods is very difficult because they do not produce see ...
Mesoderm tissue development in Drosophila melanogaster Abstract
... Since the gene is conserved, it suggests that CG11148 may have an important function in the fruit fly. CG7224 contains an unknown protein domain Searches on the protein domains in CG7224 showed that it is in the DUF1674 family. The domain is 60 amino acids long, over half the length of CG7224. Queri ...
... Since the gene is conserved, it suggests that CG11148 may have an important function in the fruit fly. CG7224 contains an unknown protein domain Searches on the protein domains in CG7224 showed that it is in the DUF1674 family. The domain is 60 amino acids long, over half the length of CG7224. Queri ...
Spotted
... - Gene Ontology is a “controlled vocabulary that can be applied to all eukaryotes “. Each gene product is classified in one or more categories. - Is distribution of missexpressed genes significantly different from the one of our initial set of genes? - maybe ash2 acts predominantly upon a group of g ...
... - Gene Ontology is a “controlled vocabulary that can be applied to all eukaryotes “. Each gene product is classified in one or more categories. - Is distribution of missexpressed genes significantly different from the one of our initial set of genes? - maybe ash2 acts predominantly upon a group of g ...
Gene Section TRA@ (T cell Receptor Alpha) Atlas of Genetics and Cytogenetics
... between the TRAV and TRAJ segments. V-Jrearrangements in the TRA locus therefore result in deletion of the TRD genes localized on the same chromosome. That deletion occurs in two steps, that is a deletion of the TRD genes, involving specific sequences located upstream from TRDC (sequence pseudo J al ...
... between the TRAV and TRAJ segments. V-Jrearrangements in the TRA locus therefore result in deletion of the TRD genes localized on the same chromosome. That deletion occurs in two steps, that is a deletion of the TRD genes, involving specific sequences located upstream from TRDC (sequence pseudo J al ...
supplementary information - Molecular Systems Biology
... shortest connection between any two elements in the global network, and thus are of questionable biological relevance. Thus every path from a seed gene to its influence targets passes through one or more of the enriched transcription factors, such that all molecular paths in the network are obtained ...
... shortest connection between any two elements in the global network, and thus are of questionable biological relevance. Thus every path from a seed gene to its influence targets passes through one or more of the enriched transcription factors, such that all molecular paths in the network are obtained ...
Text S1.
... distributions, we calculated the difference in mean expression of genes residing in pathways with somewhat opposing operations in the cell, such as subunits of the proteasome or ribosome. While the cell may turn on genes in both pathways, some conditions might favor protein expression over degradati ...
... distributions, we calculated the difference in mean expression of genes residing in pathways with somewhat opposing operations in the cell, such as subunits of the proteasome or ribosome. While the cell may turn on genes in both pathways, some conditions might favor protein expression over degradati ...
rNAi Biotechnology: Pros and Cons for Crop Improvement
... potential limitation arises from the fact that siRNAs comprise a population of molecules representing the entire sequence of the dsRNA trigger. Although this sequence heterogeneity could make it easy to silence a family of related genes with only one construct, it also opens the door to off-target e ...
... potential limitation arises from the fact that siRNAs comprise a population of molecules representing the entire sequence of the dsRNA trigger. Although this sequence heterogeneity could make it easy to silence a family of related genes with only one construct, it also opens the door to off-target e ...
Brian Yu - Comparison of Microarrayc and RNA-Seq Analysis Methods for Single Cell Transcriptiomics
... Analysis Methods for Single Cell Transcriptomics Introduction Behavior of single cells can be explained through changes in the transcription level of the genome followed by translation of the resulting mRNA into proteins (1). Changes in gene expression levels of each cell, in turn, are controlled ...
... Analysis Methods for Single Cell Transcriptomics Introduction Behavior of single cells can be explained through changes in the transcription level of the genome followed by translation of the resulting mRNA into proteins (1). Changes in gene expression levels of each cell, in turn, are controlled ...
The mouse that roared
... are reported on page 520 of this issue. Why is this so important? It is because there can scarcely be a major area of mammalian biology or medicine to which mouse studies have not contributed in some way, often as surrogates for human studies. For genetics and development, for immunology and pharmac ...
... are reported on page 520 of this issue. Why is this so important? It is because there can scarcely be a major area of mammalian biology or medicine to which mouse studies have not contributed in some way, often as surrogates for human studies. For genetics and development, for immunology and pharmac ...
Leukaemia Section t(3;21)(q26;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... This article should be referenced as such: Huret JL, Desangles F. t(3;21)(q26;q22). Cytogenet Oncol Haematol.1998;2(1):24-25. ...
... This article should be referenced as such: Huret JL, Desangles F. t(3;21)(q26;q22). Cytogenet Oncol Haematol.1998;2(1):24-25. ...
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... PWS–AS region was accompanied by (or perhaps caused by) the fusion of SNRPN and UBE3A and the evolution of the ICR. Concurrently, SNURF and the snoRNAs were acquired, and MKRN3, MAGEL2 and NDN were retroposed into this domain. This occurred after the divergence of eutherians and marsupials 180 MYA, ...
... PWS–AS region was accompanied by (or perhaps caused by) the fusion of SNRPN and UBE3A and the evolution of the ICR. Concurrently, SNURF and the snoRNAs were acquired, and MKRN3, MAGEL2 and NDN were retroposed into this domain. This occurred after the divergence of eutherians and marsupials 180 MYA, ...