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Gene Section PAX5 (paired box gene 5) Atlas of Genetics and Cytogenetics
Gene Section PAX5 (paired box gene 5) Atlas of Genetics and Cytogenetics

... lineage-specific transcription factor present at early but not late stages of differentiation. Genes Dev. 1990 May;4(5):849-59 ...
Myriad myPath® Melanoma Technical Specifications
Myriad myPath® Melanoma Technical Specifications

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17_Learning_Objectives

... 15. Explain the general process of transcription, including the three major steps of initiation, elongation, and termination. 16. Explain how RNA is modified after transcription in eukaryotic cells. 17. Describe the functional and evolutionary significance of introns. 18. Explain why, due to alterna ...
Pennisi E
Pennisi E

... With the first enhancers in hand, Levine and his colleagues were ready to take the next step: to figure out how enhancers orchestrate development and effect the changes underlying evolution. They began to dissect the architecture of these bits of sequence, determining exactly where the transcription ...
Data
Data

Exercise 2 — Zebrafish
Exercise 2 — Zebrafish

... (b) Is rs1801133 a Missense variation in all transcripts of the MTHFR gene? (c) Why are the alleles for this variation in Ensembl given as G/A and not as C/T, as in dbSNP and literature? (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=1801133) (d) What is the major allele in rs1801133? (e) ...
Homeotic Genes
Homeotic Genes

Microarray Analysis of Drosophila Development During
Microarray Analysis of Drosophila Development During

Aslibekyan and team identify novel loci associated with BMI and
Aslibekyan and team identify novel loci associated with BMI and

... assistant professor Degui Zhi, PhD, and professor Hemant K. Tiwari, PhD, in the Department of Biostatistics, Section on Statistical Genetics. The study measured DNA methylation patterns in CD4+ T-cells using the Illumina Infinium HumanMethylation450 array in a total of 991 participants of the Geneti ...
Tutorial_9_NEW
Tutorial_9_NEW

... Searching for sequences that fold to a hairpin ~70 nt -RNAfold -other efficient algorithms for identifying stem loops Concentrating on intragenic regions and introns - Filtering coding regions Filtering out non conserved candidates -Mature and pre-miRNA is usually evolutionary conserved ...
Lecture 8 Annotating Gene Lists
Lecture 8 Annotating Gene Lists

... • Null distribution of 1000 ES for geneset Null distribution of enrichment scores ...
Package `GESTr`
Package `GESTr`

... Numeric value indicating normal distribution quantile to be used for calling replicate group similarity, used in estimating Rocke-Durbin error model parameters. ...
ppt
ppt

Genome sequencing and analysis of Aspergillus oryzae
Genome sequencing and analysis of Aspergillus oryzae

... programs, algorithms and symbols are same with those in Fig. 3. Supplementary Figure S6. Phylogenetic analysis of metabolic genes. Phylogenetic relationship of pyruvate decarboxylase (a), saccharopine dehydrogenase, homoaconitase and saccharopine dehydrogenase (NADP+, L-glutamate forming) in lysine ...
REVIEW Epigenetics in disease and cancer
REVIEW Epigenetics in disease and cancer

Document
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... 3. Since multiple genes are associated with same or similar disease phenotypes, it is reasonable to expect the underlying genes to be functionally related. 4. Such functional relatedness (common pathway, interaction, biological process, etc.) can be exploited to aid in the finding of novel disease g ...
Control of Vascular Cell Differentiation by Homeobox Transcription
Control of Vascular Cell Differentiation by Homeobox Transcription

... expression of Hex can activate the endogenous SMemb gene in VSMCs or act globally to promote the conversion of VSMCs to the synthetic phenotype in a manner similar to HOXB7. Homeobox genes, such as HOXB7 and possibly Hex, are likely to be involved in promoting dedifferentiation and proliferation of ...
Genetic Analysis of the Putative Streptolysin O Regulator from
Genetic Analysis of the Putative Streptolysin O Regulator from

... bacteria). Although not considered part of the normal flora, it has been concluded that a small number of individuals can carry the organism asymptomatically (without showing signs of infection), particularly in the nasopharynx (area between the nasal cavity and the throat), skin, vagina, and anus. ...
Gene Section FSTL3 (follistatin-like 3 (secreted glycoprotein)) Atlas of Genetics and Cytogenetics
Gene Section FSTL3 (follistatin-like 3 (secreted glycoprotein)) Atlas of Genetics and Cytogenetics

... Similar to follistatin, secreted FSTL3 was shown to bind activin A and with lower affinity several other members of the TGF beta family including activin B, myostatin and BMP2, BMP6, and BMP7 (but excluding for instance TGF beta and BMP4) (Tsuchida et al., 2000; Tortoriello et al., 2001; Sidis et al ...
A two-component system is required for colonization
A two-component system is required for colonization

... In order to adapt to changing environments, bacteria have evolved two-component systems (TCSs) that are able to sense and respond to environmental stimuli. The signal perception relies on a sensor protein whose activation allows rapid adaptation through transcriptional regulation achieved by the reg ...
text s9: yellow/major royal jelly protein family
text s9: yellow/major royal jelly protein family

... as they are part of the Y-c clade). Finally, the MRJP subfamiliy is restricted to Hymenoptera, and characterized by independent expansions in all three represented taxa, as all are more closely related to their intraspecific paralogues than to genes in other taxa. Although only three complete MRJP g ...
Molecular Mechanism of Shoot Determinacy and Flowering in
Molecular Mechanism of Shoot Determinacy and Flowering in

... genes. In Arabidopsis, a facultative long day plant, more than 50 genes have been identified that are involved in the signaling pathway of flowering and flower development (Blasquez 2000). Many of these genes are transcription factors, such as the FLOWERING LOCUS C (FLC, Sheldon et al., 2000), CONSTANS ...
A global test for groups of genes
A global test for groups of genes

... Study: 18 patients with UICC II colon cancer, 18 patients with UICC III colon cancer, HG-U133A, 22.283 probesets representing ~18.000 genes. Snap-frozen material, laser microdisection. Question 1: Is the differential gene expression between UICC II /III patients more distinct for genes in cancer rel ...
Leukaemia Section t(10;17)(p15;q21) ZMYND11/MBTD1 Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(10;17)(p15;q21) ZMYND11/MBTD1 Atlas of Genetics and Cytogenetics in Oncology and Haematology

... which are known to maintain the transcriptionally repressive state of genes, probably via chromatin remodeling (Nady et al., 2012). ...
Document
Document

... could be A type with a genotype of IAIA and IAi could be B type with a genotype of IBIB or Ibi could be AB type with a genotype of IAIB could also be O type with a genotype of ii ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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