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fulltext - DiVA portal
fulltext - DiVA portal

... research. Ideally, such database searches should be part of the routine experimental design and validation, similar to making a literature search. However, the scale and complexity of many repositories often acts as a barrier to their use by basic researchers. For example, finding relevant experimen ...
Lateral gene transfer between prokaryotes and multicellular
Lateral gene transfer between prokaryotes and multicellular

... transfer of a gene into the host from other microbial symbionts may have compensated for the deterioration of the gene in Buchnera, producing a selective advantage for the laterally transferred copy. Although symbiont-host lateral transfer is both surprising and exciting at first sight, retrospectiv ...
BMC Biology - BioMedSearch
BMC Biology - BioMedSearch

... transfer of a gene into the host from other microbial symbionts may have compensated for the deterioration of the gene in Buchnera, producing a selective advantage for the laterally transferred copy. Although symbiont-host lateral transfer is both surprising and exciting at first sight, retrospectiv ...
Host-induced epidemic spread of the cholera
Host-induced epidemic spread of the cholera

... in order to test if the hyperinfectious phenotype was maintatined. • V.cholerae samples that were freshly shed were diluted in pond water that was free from contaminants of V.cholerae • Incubation at room temperature for 5 hrs, then diluted samples were mixed with in vitro grown competitor ...
Document
Document

... heat shock proteins and chaperons) are highly expressed at 48˚C than are at lower temperatures, indicating that the fungus is under heat stress. 2. More putative virulence genes (ex. those coding for the proteins responsive to oxidative stress and host immune system and for toxin production) are hig ...
Biological information flow
Biological information flow

... Cis-acting element : DNA sequences that regulate expression of gene located on same DNA molecule Inr: initiator element ...
lecture12-motif-finding
lecture12-motif-finding

... TFs bind to upstream regulatory regions of genes to either attract or block an RNA polymerase ...
Chromosomes and Phenotype
Chromosomes and Phenotype

Cis-Regulatory Timers for Developmental Gene
Cis-Regulatory Timers for Developmental Gene

... How might multiple Bra-binding sites in a notochord CRM determine early onset of gene expression? One explanation is that the cluster of several sites might increase the overall affinity of the CRM for the transcription factor [19]. In this case, the CRM with the highest biochemical affinity will be ...
Chapter 15: The Chromosomal Basis of Inheritance
Chapter 15: The Chromosomal Basis of Inheritance

... ______ ______ – used to determine the probability that crossing over between genes will occur - genes that split up due to crossing over 1% of the time are said to be ______ ______ ______ part ...
Relating genes to function: identifying enriched transcription factors
Relating genes to function: identifying enriched transcription factors

... types. We first represent each called peak by the genomic position of its apex to minimize the effect of broader peak shapes biasing our database. The significant peak calls and the apex positions are those officially released by ENCODE for unrestricted public use. Using all protein-coding genes and ...
Homeobox Genes U6[1].
Homeobox Genes U6[1].

Drosophila Workshop Presentation - UCI
Drosophila Workshop Presentation - UCI

... and light bands can be seen on the entire rear portion of the female; the last few segments of the male are fused. 4. Appearance of sex comb On males there is a tiny tuft of hairs on the front legs. 5. External genitalia on abdomen Located at the tip of the abdomen, the ovipositor of the female is p ...
new lab 9 chromosomal map
new lab 9 chromosomal map

... haploid parental genotypes . The recombinants can be most easily visualized by test crosses. Gene Linkage All the genes that are located on the same chromosome and that control the dissemination of one or two trait of certain Linkage : is a method that allows us to determine regions of chromosomes t ...
Distinct and stage specific nuclear factors regulate the expression of
Distinct and stage specific nuclear factors regulate the expression of

... RNA have been shown to be the major regulatory mechanisms in P. falciparum [4-6]. Malaria parasites express structurally distinct sets of rRNA genes in a stage specific manner that supposedly alter the properties of the ribosomes and thus modify patterns of cell growth and development [7]. Transcrip ...
04/20
04/20

... Rarely do fetuses go to term. Rarely do babies survive. Symptoms include: ...
Gene expression: Microarray data analysis
Gene expression: Microarray data analysis

Gene expression becomes heterogeneous with age
Gene expression becomes heterogeneous with age

Gene Section POU4F1 (POU class 4 homeobox 1) in Oncology and Haematology
Gene Section POU4F1 (POU class 4 homeobox 1) in Oncology and Haematology

... Brn-3a proteins act as transcription factors to regulate the expression of target genes, which can alter cell fate. In neuron, Brn-3a protects cells from apoptosis (by transactivating anti-apoptotic genes while repressing expression of pro-apoptotic proteins -see below). Brn3a also enhances differen ...
An Escherichia coli Host Strain Useful for Efficient
An Escherichia coli Host Strain Useful for Efficient

... 500-ml volumes of several cultures (data not shown). For several target genes, we also compared the magnitude of overexpression achieved by NaCl induction in GJ1158 with that achieved by IPTG in strain BL21(DE3) and found it to be more or less similar (data not shown, but see Fig. 3). Several target ...
Mathematical modeling reveals additional links between
Mathematical modeling reveals additional links between

... for TOC1 . We systematically coupled NPR1 to TOC1 and to two other circadian clock genes X and Y from the P2012 model . For each X, Y pair, we used nonlinear least squares fitting to find those NPR1 parameters that best fit our TO C1p:LUC data sets . We repeated this procedure for all X, Y pairwise ...
7/23 - Utexas
7/23 - Utexas

... The interaction of these two proteins explains their affect on a single trait (in fruit flies). ...
Applications of RNA minimum free energy computations
Applications of RNA minimum free energy computations

... Markov models (Baldi et al., 1994; Eddy et al. 1995) (see g409201), neural networks (Nielsen et al., 1997)(see g409201) and support vector machines (Vert, 2002) (see g409416). While accurate detection of protein coding genes can be achieved using hidden Markov models (Borodovsky and McIninch, 1993), ...
Using genome browsers
Using genome browsers

... • Should be straight-forward, but...lets try it out: See the course page for 3 mouse sequences in the blat_seqs file – I will do one in real-time • Assume these are new sequences that you must say whether they are good enough to be part of the genome browser ...
Use of Virus-Like-Particles in Biotechnology
Use of Virus-Like-Particles in Biotechnology

... VLPs are supra-molecular assemblages incorporating the key immunologic features of viruses which include repetitive surface patterns and particulate structures with potential for induction of innate and adaptive immunity through activation of pattern recognition receptors and antigen-specific B-cell ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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