Functional analysis of the regulatory region of a zein gene in
... The transcription of zein genes in maize is tissue-specific and developmentally regulated. The 5' regulatory region of many zein genes contains two promoters, P1 and P2, lying approximately 1000 bases apart. The promoter/enhancer activity of various fragments of the two promoter regions of the zein ...
... The transcription of zein genes in maize is tissue-specific and developmentally regulated. The 5' regulatory region of many zein genes contains two promoters, P1 and P2, lying approximately 1000 bases apart. The promoter/enhancer activity of various fragments of the two promoter regions of the zein ...
Understanding mechanisms of novel gene expression in
... that this discrepancy might be reconciled if dosage requirements play an important role in the selective environment of gene duplicates. Variation in dosageregulated gene expression created by polyploidy might be a key component of the selective environment for some duplicate genes, especially those ...
... that this discrepancy might be reconciled if dosage requirements play an important role in the selective environment of gene duplicates. Variation in dosageregulated gene expression created by polyploidy might be a key component of the selective environment for some duplicate genes, especially those ...
File
... The answer to these questions, as Thomas Hunt Morgan first realized in 1910, is yes. Morgan’s research on fruit flies led him to the principle of linkage. After identifying more than 50 Drosophila genes, Morgan discovered that many of them appeared to be “linked” together in ways that, at first glan ...
... The answer to these questions, as Thomas Hunt Morgan first realized in 1910, is yes. Morgan’s research on fruit flies led him to the principle of linkage. After identifying more than 50 Drosophila genes, Morgan discovered that many of them appeared to be “linked” together in ways that, at first glan ...
Multiple Knockout Analysis of Genetic Robustness in the Yeast
... quadruples, overall involving 157 contributing genes. The gene knockout sampling method identified an additional 174 contributing genes with k-robustness levels greater than four. Overall, the contributing genes total 74% of the tested genes, compared with only 10% of the genes that are identified i ...
... quadruples, overall involving 157 contributing genes. The gene knockout sampling method identified an additional 174 contributing genes with k-robustness levels greater than four. Overall, the contributing genes total 74% of the tested genes, compared with only 10% of the genes that are identified i ...
U6 snRNA genes of Arabidopsis are transcribed
... and 7SK (17,18) RNAs in vertebrates are transcribed by pol HI but do not require any intragenic elements. Instead, their activity depends upon three upstream signals: the Distal and Proximal Sequence Elements (DSE and PSE), and an AT-rich box which resembles the TATA box found in mRNA genes. The fir ...
... and 7SK (17,18) RNAs in vertebrates are transcribed by pol HI but do not require any intragenic elements. Instead, their activity depends upon three upstream signals: the Distal and Proximal Sequence Elements (DSE and PSE), and an AT-rich box which resembles the TATA box found in mRNA genes. The fir ...
Rich Probabilistic Models for Genomic Data
... Find parameter estimates which make observed data most likely General approach, as long as tractable likelihood function exists Can use all available information ...
... Find parameter estimates which make observed data most likely General approach, as long as tractable likelihood function exists Can use all available information ...
Identification and Characterization of a Novel Human Testis
... and protein structure. We further present extensive tissue expression studies and demonstrate that, in addition to testis, which shows the highest expression, the gene is expressed at low levels in prostate, female breast, placenta, ovary, and thymus. Moreover, we examined TSKS expression in human t ...
... and protein structure. We further present extensive tissue expression studies and demonstrate that, in addition to testis, which shows the highest expression, the gene is expressed at low levels in prostate, female breast, placenta, ovary, and thymus. Moreover, we examined TSKS expression in human t ...
Developing a CRISPR/Cas9 System for Volvox Carteri
... targeted mutations. The Cas9/CRISPR system is simpler and more precise than previously developed genome editing systems. The high precision is due to the CRISPR associated (Cas) endonuclease’s ability to bind DNA via associated guide RNAs. Cas endonucleases can delete or add bases to the genome, whi ...
... targeted mutations. The Cas9/CRISPR system is simpler and more precise than previously developed genome editing systems. The high precision is due to the CRISPR associated (Cas) endonuclease’s ability to bind DNA via associated guide RNAs. Cas endonucleases can delete or add bases to the genome, whi ...
Analyzing stochastic transcription to elucidate the nucleoid`s
... The advent of a new technology offers the opportunity to look at an old problem from a new and different point of view. It might confirm, confute or add new hypotheses. Indeed, since their arrival at the end of the 1980s [5,6], microarrays have been used to explore the chromosomal organization at a ...
... The advent of a new technology offers the opportunity to look at an old problem from a new and different point of view. It might confirm, confute or add new hypotheses. Indeed, since their arrival at the end of the 1980s [5,6], microarrays have been used to explore the chromosomal organization at a ...
Leukaemia Section t(5;12)(q31;p13) in MDS, AML and AEL in Oncology and Haematology
... blot analysis detected high levels of ACS2 expression in brain, fetal liver, and bone marrow, and the gene was found to be highly conserved in man and rat. The ETV6/ACSL6 fusion transcripts showed an out-frame fusion of exon 1 of ETV6 to exon 1 of ACSL6 in the AEL patient, an out-frame fusion of exo ...
... blot analysis detected high levels of ACS2 expression in brain, fetal liver, and bone marrow, and the gene was found to be highly conserved in man and rat. The ETV6/ACSL6 fusion transcripts showed an out-frame fusion of exon 1 of ETV6 to exon 1 of ACSL6 in the AEL patient, an out-frame fusion of exo ...
Leukaemia Section t(12;18)(p13;q12) Atlas of Genetics and Cytogenetics
... effects, could cooperate with other additional aberrations to the development of AML in this patient. ...
... effects, could cooperate with other additional aberrations to the development of AML in this patient. ...
Gene Section MSF (MLL septin-like fusion) Atlas of Genetics and Cytogenetics
... Hybrid/Mutated gene 5' MLL - 3' MSF; fusion at MLL exon 5; the reciprocal MSF-MLL is also transcribed, but out of frame. Abnormal protein NH2 - AT hook and DNA methyltransferase from MLL fused to most of MSF in COOH. ...
... Hybrid/Mutated gene 5' MLL - 3' MSF; fusion at MLL exon 5; the reciprocal MSF-MLL is also transcribed, but out of frame. Abnormal protein NH2 - AT hook and DNA methyltransferase from MLL fused to most of MSF in COOH. ...
Photosynthesis
... These enzymes are encoded by three structural genes which are adjacent to one another on the chromosome. They are controlled by one regulator gene that codes for a one repressor. ...
... These enzymes are encoded by three structural genes which are adjacent to one another on the chromosome. They are controlled by one regulator gene that codes for a one repressor. ...
Leukaemia Section t(3;12)(q26;q21) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differsntiation. ...
... likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differsntiation. ...
Gene Expression Analysis
... Advanced neural learning algorithms have not only improved the accuracy, reliability and efficiency of many medical pattern recognition systems, but they also show several advantages for the implementation of decision support systems in physiological genomics [4]. Tamayo et al. have illustrated the ...
... Advanced neural learning algorithms have not only improved the accuracy, reliability and efficiency of many medical pattern recognition systems, but they also show several advantages for the implementation of decision support systems in physiological genomics [4]. Tamayo et al. have illustrated the ...
Making Sense of Complicated Microarray Data
... concluded to be differentially expressed, because we have decided to “live with” a p-value of 0.01 If only one gene were being studied, a 1% margin of error might not be a big deal, but 100 false conclusions in one study? That doesn’t sound too good. ...
... concluded to be differentially expressed, because we have decided to “live with” a p-value of 0.01 If only one gene were being studied, a 1% margin of error might not be a big deal, but 100 false conclusions in one study? That doesn’t sound too good. ...
microarrays part2
... the values for the missing features (with weights) EM approach (even better)– iteratively define classes based on the current approximation, and re-estimate the missing features based only on genes in these groups. Repeat until convergence. Or use just the available data – less noise but have to nor ...
... the values for the missing features (with weights) EM approach (even better)– iteratively define classes based on the current approximation, and re-estimate the missing features based only on genes in these groups. Repeat until convergence. Or use just the available data – less noise but have to nor ...
Use of methylation profiling to identify genes involved in relapse in
... are usually methylation free. In cancerous cells these same regions frequently exhibit hypermethylation, leading to stable gene inactivation. ...
... are usually methylation free. In cancerous cells these same regions frequently exhibit hypermethylation, leading to stable gene inactivation. ...
Microarray Lessons Packet - McCarter Biology
... 1. A group of geneticists recently discovered a genetic link to violent criminal behavior. In their studies, over 65% of prisoners have 3 genes involved in the study compared to only 8% of the general public. There has been a push by some local politicians to have everyone arrested tested for these ...
... 1. A group of geneticists recently discovered a genetic link to violent criminal behavior. In their studies, over 65% of prisoners have 3 genes involved in the study compared to only 8% of the general public. There has been a push by some local politicians to have everyone arrested tested for these ...