Part 1 Microarray Timeseries Analysis with replicates OSM
... 1. Permute the n data points for the gene (x). The first n1 are referred to as “treatments”, the second n2 as “controls”. 2. For each gene, calculate the corresponding two sample t-statistic, tb. After all the B permutations are done: ...
... 1. Permute the n data points for the gene (x). The first n1 are referred to as “treatments”, the second n2 as “controls”. 2. For each gene, calculate the corresponding two sample t-statistic, tb. After all the B permutations are done: ...
Document
... promoter downstream from it, because reading through the downstream promoter prevents the necessary transcription factors from binding to it. The RNA transcribed from the upstream promoter has no coding function. ...
... promoter downstream from it, because reading through the downstream promoter prevents the necessary transcription factors from binding to it. The RNA transcribed from the upstream promoter has no coding function. ...
Human chromosome 21/Down syndrome gene function and
... to be for some time to come. Gene lists need frequent updating and revisions, in part to keep up with novel entries in dbEST which add both new gene models and alternative splice variants of existing gene models. Gene lists also need curation. For example, Imanishi et al. (2004) recently reported 19 ...
... to be for some time to come. Gene lists need frequent updating and revisions, in part to keep up with novel entries in dbEST which add both new gene models and alternative splice variants of existing gene models. Gene lists also need curation. For example, Imanishi et al. (2004) recently reported 19 ...
Pair-rule genes
... Lewis did pioneering research on late embryogenesis, who discovered homeotic mutants mutant flies in which structures characteristic of one part of the embryo are found at some ...
... Lewis did pioneering research on late embryogenesis, who discovered homeotic mutants mutant flies in which structures characteristic of one part of the embryo are found at some ...
short communication
... of human neuronatin cDNA, but not with the probe specific for the 5’ -end. These results suggested that the 6-kb BamHI fragment may contain the complete neuronatin gene, with the 2.3-kb BamHI-EcoRI fragment encoding the promoter and operator regions. Therefore, these two fragments (2.3 and 3.7 kb) w ...
... of human neuronatin cDNA, but not with the probe specific for the 5’ -end. These results suggested that the 6-kb BamHI fragment may contain the complete neuronatin gene, with the 2.3-kb BamHI-EcoRI fragment encoding the promoter and operator regions. Therefore, these two fragments (2.3 and 3.7 kb) w ...
Clustering Gene Expression Data: The Good, The Bad, and
... • The ideal approach is to get a set of new observations, with known class label and see how frequently the classifier makes the correct prediction. • Performance on the training set is a poor approach, and will deflate the error estimate. • Cross validation methods are used to get less biased estim ...
... • The ideal approach is to get a set of new observations, with known class label and see how frequently the classifier makes the correct prediction. • Performance on the training set is a poor approach, and will deflate the error estimate. • Cross validation methods are used to get less biased estim ...
A worm that turned - Gesundheitsindustrie BW
... Around 540 million years ago (Early Cambrian), there were animals that can be differentiated into protostomes (e.g. arthropods) and deuterostomes (e.g. the Haikouichthys shown in the photo). It is believed that the bilaterians’ hypothetical last common ancestors, the urbilaterians (also referred to ...
... Around 540 million years ago (Early Cambrian), there were animals that can be differentiated into protostomes (e.g. arthropods) and deuterostomes (e.g. the Haikouichthys shown in the photo). It is believed that the bilaterians’ hypothetical last common ancestors, the urbilaterians (also referred to ...
Nucleic acids and their protein partners
... without the help of proteins. Electrostatics is a dominant force in RNA folding, but recent theoretical, computational, and experimental investigations have revealed the interplay of counterions, RNA structure and folding pathways. New structural methods, including timeresolved footprinting, small-a ...
... without the help of proteins. Electrostatics is a dominant force in RNA folding, but recent theoretical, computational, and experimental investigations have revealed the interplay of counterions, RNA structure and folding pathways. New structural methods, including timeresolved footprinting, small-a ...
FEBS Lett. 586, 2043-2048 - iSSB
... chromosomes leads to transient gene dosage effects. Indeed, DNA replication must be initiated once per cell cycle, while it may take longer than one generation time and particularly so at high growth rates (Fig. 1b). It appears that dozens of replication forks may be simultaneously present in the ce ...
... chromosomes leads to transient gene dosage effects. Indeed, DNA replication must be initiated once per cell cycle, while it may take longer than one generation time and particularly so at high growth rates (Fig. 1b). It appears that dozens of replication forks may be simultaneously present in the ce ...
Chromatin, DNA methylation and neuron gene regulation — the
... enzymes) is more informative than a linear pattern of sitespecific markings analyzed at the single-nucleotide level (assayed using bisulfite modification). There is also the question of which locus should be given priority: a locus within the sequence of a transcription factor binding site or one el ...
... enzymes) is more informative than a linear pattern of sitespecific markings analyzed at the single-nucleotide level (assayed using bisulfite modification). There is also the question of which locus should be given priority: a locus within the sequence of a transcription factor binding site or one el ...
MultiBac Expression System User Manual
... We describe here in detail new baculovirus transfer vectors constructed specifically for multigene applications. We present a modified recipient baculovirus DNA for these transfer vectors engineered for improved protein production, and a simple and rapid method to integrate genes via two access site ...
... We describe here in detail new baculovirus transfer vectors constructed specifically for multigene applications. We present a modified recipient baculovirus DNA for these transfer vectors engineered for improved protein production, and a simple and rapid method to integrate genes via two access site ...
Clustering2_11-8
... Is it possible that some of these gene expression changes are miscalled (i.e. biologically significant but insignificant p value and vice versa) and why? What other criteria might you use to distinguish genes you care about? How many genes pass the cutoff of q<0.01 and how does this compare to the n ...
... Is it possible that some of these gene expression changes are miscalled (i.e. biologically significant but insignificant p value and vice versa) and why? What other criteria might you use to distinguish genes you care about? How many genes pass the cutoff of q<0.01 and how does this compare to the n ...
fulltext - DiVA portal
... research. Ideally, such database searches should be part of the routine experimental design and validation, similar to making a literature search. However, the scale and complexity of many repositories often acts as a barrier to their use by basic researchers. For example, finding relevant experimen ...
... research. Ideally, such database searches should be part of the routine experimental design and validation, similar to making a literature search. However, the scale and complexity of many repositories often acts as a barrier to their use by basic researchers. For example, finding relevant experimen ...