Altering gene expression by aminocoumarins: the role of DNA
... We previously showed that different aminocoumarins cause severe inhibition of recA transcription [20]. This effect is likely mediated by the known inhibition of the GyrB subunit. To verify this assumption, a strain expressing a non-susceptible GyrB enzyme was analysed. A mutated gyrB gene (Ile102Ser ...
... We previously showed that different aminocoumarins cause severe inhibition of recA transcription [20]. This effect is likely mediated by the known inhibition of the GyrB subunit. To verify this assumption, a strain expressing a non-susceptible GyrB enzyme was analysed. A mutated gyrB gene (Ile102Ser ...
Identification and Clustering of Genes Expressed In Circadian
... called Mop3 has been identified as a key regulator of circadian rhythms in mammals (Bunger et al., 2000). It would be useful to understand these regulatory networks because they may yield insight into the regulation of circadian behaviors in humans, and may help develop ...
... called Mop3 has been identified as a key regulator of circadian rhythms in mammals (Bunger et al., 2000). It would be useful to understand these regulatory networks because they may yield insight into the regulation of circadian behaviors in humans, and may help develop ...
Analysis of a Rhizobium leguminosarum gene
... A novel Rhizobium leguminosarum gene, gstA, the sequence of which indicated that it was a member of the gene family of glutathione Stransferases (GSTs), was identified. The homology was greatest to the GST enzymes of higher plants. The Rhizobium gstA gene was normally expressed at a very low level. ...
... A novel Rhizobium leguminosarum gene, gstA, the sequence of which indicated that it was a member of the gene family of glutathione Stransferases (GSTs), was identified. The homology was greatest to the GST enzymes of higher plants. The Rhizobium gstA gene was normally expressed at a very low level. ...
Cortical EEG correlates of successful memory encoding
... information. Thus, perceptual and conceptual features as well as contextual details and self-generated thoughts that pertain to the current episode need to be co-activated during encoding to give rise to new memories. 2.1. Studying successful memory encoding with the subsequent memory paradigm In ad ...
... information. Thus, perceptual and conceptual features as well as contextual details and self-generated thoughts that pertain to the current episode need to be co-activated during encoding to give rise to new memories. 2.1. Studying successful memory encoding with the subsequent memory paradigm In ad ...
Conservation and Coevolution in the Scale
... Fraser, Wall, and Hirsh 2003). A recent study that dealt with several such relationships simultaneously demonstrated correlations between different measures of evolutionary conservation and various functional genomic parameters (Krylov et al. 2003). However, the findings of some of these evolutionar ...
... Fraser, Wall, and Hirsh 2003). A recent study that dealt with several such relationships simultaneously demonstrated correlations between different measures of evolutionary conservation and various functional genomic parameters (Krylov et al. 2003). However, the findings of some of these evolutionar ...
This article appeared in a journal published by Elsevier. The
... by these DNA vaccines through intramuscular immunization. The IgG subclass (IgG1 and IgG2a) analysis indicates that divalent DNA vaccine induces both Th1 and Th2 immune responses. The protective efficacy was evaluated by the survival against lethal challenge with A. pleuropneumoniae serotype 1. The g ...
... by these DNA vaccines through intramuscular immunization. The IgG subclass (IgG1 and IgG2a) analysis indicates that divalent DNA vaccine induces both Th1 and Th2 immune responses. The protective efficacy was evaluated by the survival against lethal challenge with A. pleuropneumoniae serotype 1. The g ...
LacZ Reporter Gene Expression in 81 KOMP Heterozygous Mutants
... sections has a similar anatomical distribution and is observed less frequently than that found with whole-mounts. ...
... sections has a similar anatomical distribution and is observed less frequently than that found with whole-mounts. ...
Ramamoorthy, Krithika : Critical Review of Methods available for Microarray Data Analysis
... expressions of differential expression. False negatives are failures to detect true differential expression. Regardless of the test statistic used (false negative rate or false positive rate), one needs to convert it to a p value to determine its significance. Standard methods for estimating p value ...
... expressions of differential expression. False negatives are failures to detect true differential expression. Regardless of the test statistic used (false negative rate or false positive rate), one needs to convert it to a p value to determine its significance. Standard methods for estimating p value ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... beetle), was amplified through Polymerase chain reaction (PCR) by using specific primers. The gene was ligated to a cloning vector pGEM-T and was cloned into an E.coli strain DH5α. The positive clones were screened for the cry gene content. The partial sequencing of the cloned gene from this strain ...
... beetle), was amplified through Polymerase chain reaction (PCR) by using specific primers. The gene was ligated to a cloning vector pGEM-T and was cloned into an E.coli strain DH5α. The positive clones were screened for the cry gene content. The partial sequencing of the cloned gene from this strain ...
Journal Club Pack - Circulation Research
... although we have previously shown that phenotypic switching of cultured SMC is dependent on Krupplelike factor (KLF)4. Objective: The goals of the present studies were to ascertain if (1) injury-induced repression of SM22α gene after vascular injury is mediated through KLF4 binding to the G/C Repres ...
... although we have previously shown that phenotypic switching of cultured SMC is dependent on Krupplelike factor (KLF)4. Objective: The goals of the present studies were to ascertain if (1) injury-induced repression of SM22α gene after vascular injury is mediated through KLF4 binding to the G/C Repres ...
Brain oscillations and memory - Wellcome Trust Centre for
... improved object decoding compared to spike-rate alone. Also, maximal information in spikes about the identity of the first presented object was found in an earlier phase of the 32 Hz LFP cycle than information about the second object. This was accompanied by a significant modulation of the amplitude ...
... improved object decoding compared to spike-rate alone. Also, maximal information in spikes about the identity of the first presented object was found in an earlier phase of the 32 Hz LFP cycle than information about the second object. This was accompanied by a significant modulation of the amplitude ...
View/Open
... rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattle, accelerated development is already evident in XY blastocysts; cell division among male embryos occurs more rapidly than in female embryos [38] and, in humans, boys gro ...
... rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattle, accelerated development is already evident in XY blastocysts; cell division among male embryos occurs more rapidly than in female embryos [38] and, in humans, boys gro ...
Accelerated gene evolution through replication
... found on the lagging strand, indicating faster adaptive evolution in many genes in the head-on orientation. Increased gene length and gene expression amounts are positively correlated with the rate of accumulation of nonsynonymous mutations in the head-on genes, suggesting that the conflict between ...
... found on the lagging strand, indicating faster adaptive evolution in many genes in the head-on orientation. Increased gene length and gene expression amounts are positively correlated with the rate of accumulation of nonsynonymous mutations in the head-on genes, suggesting that the conflict between ...
PDF
... Fig. 1. ACF1 expression is developmentally regulated. Wholemount immunofluorescence microscopy (IFM) was performed on different developmental stages of Drosophila. ACF1 is very abundant at early embryonic stages (A,B), but its expression is progressively restricted to subsets of cells (C) and genera ...
... Fig. 1. ACF1 expression is developmentally regulated. Wholemount immunofluorescence microscopy (IFM) was performed on different developmental stages of Drosophila. ACF1 is very abundant at early embryonic stages (A,B), but its expression is progressively restricted to subsets of cells (C) and genera ...
KAIE LOKK Comparative genome-wide DNA methylation
... correlations, tissue-specific differentially methylated regions have been increasingly found among intragenic regions, such as in gene bodies or even in intergenic regions. But the relationship between DNA methylation in nonpromoter regions and gene expression remains unclear. Cancer, especially lun ...
... correlations, tissue-specific differentially methylated regions have been increasingly found among intragenic regions, such as in gene bodies or even in intergenic regions. But the relationship between DNA methylation in nonpromoter regions and gene expression remains unclear. Cancer, especially lun ...
Microarray expression data
... * the SVM is used then to recognize and classify the genes in the data set to the established groups on the basis of their expression * the SVM can also identify genes in the training set that are outliers or that have been previously assigned to the incorrect class * an application of potentially g ...
... * the SVM is used then to recognize and classify the genes in the data set to the established groups on the basis of their expression * the SVM can also identify genes in the training set that are outliers or that have been previously assigned to the incorrect class * an application of potentially g ...
Soft inheritance: Challenging the Modern Synthesis
... meiotic divisions in the germline that give rise to sperm or eggs, so offspring may inherit epigenetic variations through the germline. The mechanisms that lead to cellular epigenetic inheritance can also lead to cell memory - to the persistence of functional and structural cellular states in non-di ...
... meiotic divisions in the germline that give rise to sperm or eggs, so offspring may inherit epigenetic variations through the germline. The mechanisms that lead to cellular epigenetic inheritance can also lead to cell memory - to the persistence of functional and structural cellular states in non-di ...
TTEST – Between subjects
... (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. • It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) after looking at the distribution of the test stat ...
... (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. • It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) after looking at the distribution of the test stat ...
The silence of genes
... similar species.” According to this theory, it is in the interests of both parents to maintain efficient nutrient transfer from mother to child while the two are either physically attached through the placenta or endosperm, or closely coupled, as when suckling. Indeed, there is evidence that ...
... similar species.” According to this theory, it is in the interests of both parents to maintain efficient nutrient transfer from mother to child while the two are either physically attached through the placenta or endosperm, or closely coupled, as when suckling. Indeed, there is evidence that ...
Gene regulation_1130(final)
... regulation of FAS gene expression 1. Insulin/glucose → through the proximal region of the FAS promoter → 2 to 3-fold stimulation of FAS gene expression • fasting/refeeding → 20-30 fold induction of the endogenous FAS gene ...
... regulation of FAS gene expression 1. Insulin/glucose → through the proximal region of the FAS promoter → 2 to 3-fold stimulation of FAS gene expression • fasting/refeeding → 20-30 fold induction of the endogenous FAS gene ...
Living Synaptic Vesicle Marker: Synaptotagmin-GFP
... lines were generated; one with insertion on the X chromosome, two on the second chromosome, and one on the third chromosome. All of these lines produced clear fluorescence when crossed to a pan-neuronal GAL4 driver (elav-GAL4, see Fig. 2) or a subset neuronal GAL4 driver 4G-GAL4 (data not shown). 4G ...
... lines were generated; one with insertion on the X chromosome, two on the second chromosome, and one on the third chromosome. All of these lines produced clear fluorescence when crossed to a pan-neuronal GAL4 driver (elav-GAL4, see Fig. 2) or a subset neuronal GAL4 driver 4G-GAL4 (data not shown). 4G ...
PartFourAnswers.doc
... stronger promoter (promoter "up" mutations) whereas those that make the promoter less similar to the consensus generate a weaker promoter (promoter "down" mutations). An "up" mutation would make the lac operon no longer dependent on the positive regulation by the cAMP-CAP complex (when the operon is ...
... stronger promoter (promoter "up" mutations) whereas those that make the promoter less similar to the consensus generate a weaker promoter (promoter "down" mutations). An "up" mutation would make the lac operon no longer dependent on the positive regulation by the cAMP-CAP complex (when the operon is ...
Molecular analysis of the structure and expression of the RH... individuals with D--, Dc-, and DCw- gene complexes
... RHCE gene in the DC- gene complex or the presence of an unusual band comigrating with the 19 kb D-specific fragment. The exon-specific probes used in these experiments also revealed abnormal bands in the EcoRI, HindIII, Taq I, and Pst I restriction patterns of the DC- sample (not shown). This strong ...
... RHCE gene in the DC- gene complex or the presence of an unusual band comigrating with the 19 kb D-specific fragment. The exon-specific probes used in these experiments also revealed abnormal bands in the EcoRI, HindIII, Taq I, and Pst I restriction patterns of the DC- sample (not shown). This strong ...
A CONTRIBUTION TO AN UNDERSTANDING OF CROSSING
... with balanced lethals, following certain specific crossover percentages. (It is assumed that crossing over occurs at the four strand stage. If it takes place at the two strand stage, only one-half the amount of crossing over will be necessary to produce a given percentage of segregation after selfin ...
... with balanced lethals, following certain specific crossover percentages. (It is assumed that crossing over occurs at the four strand stage. If it takes place at the two strand stage, only one-half the amount of crossing over will be necessary to produce a given percentage of segregation after selfin ...
Genomic imprinting of a placental lactogen gene in Peromyscus
... organ responsible for regulating nutrient transfer between mother and fetus, is often affected as well. Chief among the hormones used by the placenta to regulate nutrient transfer are the placental lactogens (PLs). In primates these genes arose from tandem duplications of the growth hormone gene (Ow ...
... organ responsible for regulating nutrient transfer between mother and fetus, is often affected as well. Chief among the hormones used by the placenta to regulate nutrient transfer are the placental lactogens (PLs). In primates these genes arose from tandem duplications of the growth hormone gene (Ow ...