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recognition memory: what are the roles of the perirhinal cortex and
recognition memory: what are the roles of the perirhinal cortex and

... C-FOS is commonly expressed when neurons are active ...
U6 snRNA genes of Arabidopsis are transcribed
U6 snRNA genes of Arabidopsis are transcribed

... rRNA and other types of cytoplasmic and nuclear small RNAs, including U6 snRNA (reviewed in refs 1—4). Accurate initiation by either of these enzymes requires several protein factors, most * To whom correspondence should be addressed ...
Normalization of gene expression measurements in tumor tissues
Normalization of gene expression measurements in tumor tissues

... The ‘gold-standard’ normalization gene is still the subject of debate. Currently, the best option is to measure the expression of multiple housekeeping genes and normalize using their mean expression. In cancer research, only few studies attempted to investigate the variation in expression of housek ...
Molecular Detection of Virulence Genes Associated with
Molecular Detection of Virulence Genes Associated with

... Klebsiella species are gram negative, medium sized rods (0.40.6 x 2-3 μm). They are facultative anaerobic, fermentative, catalase positive, oxidase negative lactose fermenters, reduce nitrate to nitrite and are motile by peritrichous flagella. They are capable of growth on non-enriched media such as ...
Gill: Gene Regulation II
Gill: Gene Regulation II

... • Some transcription factors have stereotypical roles as activators or repressors. Likely many can do both (in different contexts). • DNA can be bent into 3D shape preventing enhancer – promoter interactions. • Activator and co-activator proteins can be modified into inactive states. Note: repressor ...
Document
Document

... Ex. It encodes a protein predicted to contain 688 amino acid residues, including 11 zinc finger motifs of the C2H-2 type in the C-terminal region, that are Kruppellike in the conservation of the H/C link sequence connecting them. ...
Is HP1 an RNA detector that functions both in repression and
Is HP1 an RNA detector that functions both in repression and

... with a range of nuclear activities (Kellum, 2003; and references therein). Do RNA sense strands recruit transcriptional activators to sites of active transcription through HP1, while RNA double strands specify targeting of a separate class of HP1 repressing complexes to heterochromatic regions? If s ...
When 1 plus 1 equals 3 in VWD
When 1 plus 1 equals 3 in VWD

... complete aggregation, while addition of exogenous ADP produced normal aggregation responses at low thrombin concentrations. The function of PKC␣⫺/⫺ mouse platelets (which have impaired dense granule biogenesis and defective secretion of both dense and ␣-granules) can also be restored by ADP in vitro ...
Can genes create sexual preferences?
Can genes create sexual preferences?

... acids. Each group of three bases (letters) on the ladder is a code specifying one individual amino acid which should link with other amino acids, similarly produced, to form a protein. For example, the triplet GTA codes for the amino acid histidine, while GTT codes for glutamine. The sequence, types ...
Methods for reducing interference in the Complementary Learning
Methods for reducing interference in the Complementary Learning

... learning tunes a subset of the hidden units to respond more strongly to that stimulus. As these units respond more and more strongly to the stimulus, they start to inhibit other units. Thus, the neural response to a stimulus transitions from a diffuse overall response (where no units are tuned to re ...
Six3, a murine homologue of the sine oculis gene, demarcates the
Six3, a murine homologue of the sine oculis gene, demarcates the

... Drosophila so homeobox-containing gene, two novel murine genes of this type were identified and named Six1 and Six2 (Oliver et al., 1995). The expression of these genes was found to be restricted mainly to head and body mesenchyme, limb muscle and tendons. In an attempt to identify additional Six-re ...
- Murdoch Research Repository
- Murdoch Research Repository

... B. hyodysenteriae has been shown to contain an unusual prophage-like agent named VSH-1 (virus of Serpulina hyodysenteriae) that is involved in natural gene transfer and recombination within the species (Humphrey et al., 1997 and Matson et al., 2007). This agent is in a state of permanent lysogeny an ...
lecture notes
lecture notes

... 2. The first 7 divisions occur within the central yolk regions, while the next 3 divisions occur during the movement of the nuclei to the periphery. An hour after fertilization the embryo is composed of about 800 nuclei forming a monolayer around the periphery of the egg. During the next 30 min the ...
A nested deletion approach to generate Cre deleter mice with
A nested deletion approach to generate Cre deleter mice with

... Mouse genetics disposes of a set of technologies, which have made this animal a valuable model for human development, physiology and diseases. Of particular interest is the loxP/Cre recombinase system, which allows for site- or time-specific recombination of particular target sequences, hence for a ...
emboj200858-sup
emboj200858-sup

... pntP1 is expressed in two cell rows on each side of the midline. Upon expression of Rhomboid proteins by prd-Gal4, the pattern of ectopic pntP1 expression was monitored within the stripes, and adjacent to them. (A) Rho-1 induces pronounced expression of pntP1 within the stripes, and several cell row ...
BiGCaT
BiGCaT

... Create QTL Mapps and map expression results Example QTL1a With a number of (slightly) upregulated genes ...
Interactive Visualization of Gene Regulatory Networks with
Interactive Visualization of Gene Regulatory Networks with

... VisANT [11, 12] is a tool for biological network analysis and visualization. It focusses strongly on the analysis of network of various types, such as protein-protein interaction networks, gene transcription networks, metabolic pathways, and interconnections between these. Network analysis is perfor ...
Why Science Tells Us Not to Rely on Eyewitness Accounts
Why Science Tells Us Not to Rely on Eyewitness Accounts

... IN 1984 KIRK BLOODSWORTH was convicted of the rape and murder of a nine-year-old girl and sentenced to the gas chamber—an outcome that rested largely on the testimony of five eyewitnesses. After Bloodsworth served nine years in prison, DNA testing proved him to be innocent. Such devastating mistakes ...
Cloning and characterization of a gene coding for a hydrophobin Fv
Cloning and characterization of a gene coding for a hydrophobin Fv

... terms of molecular biology or molecular genetics (De Groot et al., 1996). In a commercial-scale production of mushrooms, the development of fruiting bodies is induced by controlling various environmental factors such as light, temperature, humidity, physical stimulus, and chemical stimulus. These fa ...
Genetic Profiling of Changes Underlying Different Sized Human
Genetic Profiling of Changes Underlying Different Sized Human

... between small and massive tears. Expression profiles are indicated by red (upregulation) and green (repression). DISCUSSION: This study is the first genome wide analysis of rotator cuff tears to our knowledge. The gene expression profiles of normal, small and massive RC tear groups suggested they ar ...
Two genes from Bacillus subtilis under the sole control
Two genes from Bacillus subtilis under the sole control

... (residues 6.5-77) and MILIDRVGRKKLL (residues 298-310) were found at the expected positions. Moreover, the hydrophobicity profile of YxcC with its 12 hypothetical membrane-spanning regions was similar to other porters of the major facilitator superfamily (data not shown). In keeping with the nomencl ...
Hox gene regulation by C. elegans sop-3
Hox gene regulation by C. elegans sop-3

... In particular, changes in the levels of MAB-5 and EGL-5 result in homeotic transformations of ray morphological identities that often result in ray fusions (Chow and Emmons, 1994). MAB-5 and EGL-5 are each expressed in specific subsets of the rays and are required for expression of the unique charac ...
MouseMine: Mouse Gene Lists (and a whole lot more)
MouseMine: Mouse Gene Lists (and a whole lot more)

... – Use the list of genes you find using MouseMine as input into the SNP query form @ MGI to see if there are any SNPs in these genes between the strains used to map the phenotype MGI: www.informatics.jax.org MouseMine: www.mousemine.org ...
Morgan, Thomas H. The Theory of the Gene. The American
Morgan, Thomas H. The Theory of the Gene. The American

... What genes stand for can be most easily shown by means of a few familiar illustrations. Mendel’s cross with yellow and green peas (or any similar case in which two characters are contrasted with each other as a pair) will serve as an example. In the second generation from such a cross the numerical ...
Chpt11_TxnPromoters.doc
Chpt11_TxnPromoters.doc

... Promoters contain binding sites for nuclear proteins, but which of these binding sites have a function in gene expression? This requires a genetic approach for an answer. 1. Use of "surrogate genetics" to define the promoter a. In vitro mutagenesis (deletions or point mutations) (1) Mutations of the ...
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Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
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