The causes and molecular consequences of polyploidy in
... due to elevated temperature (36°C) differs greatly at different microspore stages37. The elevated ...
... due to elevated temperature (36°C) differs greatly at different microspore stages37. The elevated ...
Lecture 35 Transgenic animals
... potentially toxic substances in the body, including drugs, has been created by scientists at The Salk Institute. Species differences in drug metabolism and responsiveness between mice and humans mean that it is difficult to extrapolate results obtained in animal trials to humans. Therefore humanised ...
... potentially toxic substances in the body, including drugs, has been created by scientists at The Salk Institute. Species differences in drug metabolism and responsiveness between mice and humans mean that it is difficult to extrapolate results obtained in animal trials to humans. Therefore humanised ...
McElwain, Mark: A Critical Review of Gene Prediction Software
... annotation of predicted genes residing in these genomes is essential to learning more about biology and the evolutionary relationships between species. In the days of classical, forward genetics, the presence of a gene was inferred from a mutant phenotype, and one could map the mutation to a locus, ...
... annotation of predicted genes residing in these genomes is essential to learning more about biology and the evolutionary relationships between species. In the days of classical, forward genetics, the presence of a gene was inferred from a mutant phenotype, and one could map the mutation to a locus, ...
doc211956 - 食品科學系
... A popcorn-like flavor compound, 2-acetyl-1-pyrroline (2-AP), has been reported as a potent flavor component of an aromatic rice, taro, pandan and bread. In order to study the molecular mechanism of 2-AP biosynthesis, we analyzed the expression profile of MG and P5C biosynthetic enzymes and the level ...
... A popcorn-like flavor compound, 2-acetyl-1-pyrroline (2-AP), has been reported as a potent flavor component of an aromatic rice, taro, pandan and bread. In order to study the molecular mechanism of 2-AP biosynthesis, we analyzed the expression profile of MG and P5C biosynthetic enzymes and the level ...
Solid Tumour Section Soft Tissue Tumors: Liposarcoma: Myxoid liposarcoma
... Oncogenic properties Transcriptional control of the fusion gene is dominated by the FUS housekeeping type of regulatory region, leading to stable expression of the fusion protein in tumor cells. The transforming properties of the FUS-DDIT3 fusion protein have been demonstrated in NIH 3T3 cells and f ...
... Oncogenic properties Transcriptional control of the fusion gene is dominated by the FUS housekeeping type of regulatory region, leading to stable expression of the fusion protein in tumor cells. The transforming properties of the FUS-DDIT3 fusion protein have been demonstrated in NIH 3T3 cells and f ...
Recombinant DNA Technology
... damaged by mutagens such as toxic chemicals, UV light, or viruses. This process prevents the development of tumors by stopping cells with damaged DNA from undergoing mitosis and passing down this damaged DNA to daughter cells. If it is determined that the DNA can be repaired p53 will activate other ...
... damaged by mutagens such as toxic chemicals, UV light, or viruses. This process prevents the development of tumors by stopping cells with damaged DNA from undergoing mitosis and passing down this damaged DNA to daughter cells. If it is determined that the DNA can be repaired p53 will activate other ...
Educational Item Section Architecture of the chromatin in the interphase Nucleus
... the transcription and therefore of the gene expression. According to its location, such or such gene group will be entirely activated without assuring an individual control of each. Furthermore, the existence of exclusion zones would facilitate the protein action assuming the transcription (enhancer ...
... the transcription and therefore of the gene expression. According to its location, such or such gene group will be entirely activated without assuring an individual control of each. Furthermore, the existence of exclusion zones would facilitate the protein action assuming the transcription (enhancer ...
BSc in Applied Biotechnology 3 BO0048 ‑ GENETICS PROGRAM
... man with normal color vision some colorblind sons are produced. • If a colorblind woman is married to a normal man, all her sons are colorblind whereas all the daughters have normal color vision. • When these daughters having normal color vision are married to a colorblind man, the colorblind grand ...
... man with normal color vision some colorblind sons are produced. • If a colorblind woman is married to a normal man, all her sons are colorblind whereas all the daughters have normal color vision. • When these daughters having normal color vision are married to a colorblind man, the colorblind grand ...
Guidelines for Production of Transgenic Mice by Pronuclear Injection
... A more uncommon problem is loss of the transgene altogether. This may be caused by meiotic recombination, as in a double-crossover event. Founders being from the hybrid CB6F1 strain, the client must decide whether to maintain a mixed background or to backcross to an inbred line. In this case it will ...
... A more uncommon problem is loss of the transgene altogether. This may be caused by meiotic recombination, as in a double-crossover event. Founders being from the hybrid CB6F1 strain, the client must decide whether to maintain a mixed background or to backcross to an inbred line. In this case it will ...
The retrieval of perceptual memory details depends on right
... unlikely to become part of a memory's gist which, according to Winocur and Moscovitch (Winocur & Moscovitch, 2011; Winocur et al., 2010), can be retained and accessed without involving the hippocampus. For these reasons, we propose that perceptual memory content is a sensitive marker of recollection ...
... unlikely to become part of a memory's gist which, according to Winocur and Moscovitch (Winocur & Moscovitch, 2011; Winocur et al., 2010), can be retained and accessed without involving the hippocampus. For these reasons, we propose that perceptual memory content is a sensitive marker of recollection ...
Sequencing technology does not eliminate biological
... is not eliminated by sequencing technology, we collected public data from two of the only RNA-sequencing experiments with a large number of biological replicates, n = 60 and n = 69, respectively13,14. We compared a subset of these sequencing data (n = 43 and 51 samples, respectively) with microarray ...
... is not eliminated by sequencing technology, we collected public data from two of the only RNA-sequencing experiments with a large number of biological replicates, n = 60 and n = 69, respectively13,14. We compared a subset of these sequencing data (n = 43 and 51 samples, respectively) with microarray ...
38891
... McShane LM, Radmacher MD, Freidlin B, Yu R, Li MC, Simon R. (2002). Methods for assessing reproducibility of clustering patterns observed in analyses of microarray data. Bioinformatics 18(11):1462-9. Zhou X, Kao MC, Wong WH. (2002). Transitive functional annotation by shortest-path analysis of gene ...
... McShane LM, Radmacher MD, Freidlin B, Yu R, Li MC, Simon R. (2002). Methods for assessing reproducibility of clustering patterns observed in analyses of microarray data. Bioinformatics 18(11):1462-9. Zhou X, Kao MC, Wong WH. (2002). Transitive functional annotation by shortest-path analysis of gene ...
Protein expression pattern in cerebellum of Cav2.1 mutant, tottering
... shown), and Ryr3 (Fig. 4) were higher than those observed in +/+ mice. Specifically, the expressions of TH and ZebrinII were dramatically increased in the Purkinje cells of tottering-6j mice. The Ryr3 expression was increased in the granular layer of tottering-6j mice. Despite the abovementioned inc ...
... shown), and Ryr3 (Fig. 4) were higher than those observed in +/+ mice. Specifically, the expressions of TH and ZebrinII were dramatically increased in the Purkinje cells of tottering-6j mice. The Ryr3 expression was increased in the granular layer of tottering-6j mice. Despite the abovementioned inc ...
Introduction to the Analysis of Microarray Data
... will be most helpful in our analysis are therefore the ones ...
... will be most helpful in our analysis are therefore the ones ...
BAP1 Presentation
... 014) including 660 pre-treated advanced MPM patients, vorinostat given as a second-line or third-line therapy did not improve overall survival. Therefore, was not recommended as a therapy in malignant pleural mesothelioma patients (Krug et al 2015). Another small phase II trial (conducted on thirtee ...
... 014) including 660 pre-treated advanced MPM patients, vorinostat given as a second-line or third-line therapy did not improve overall survival. Therefore, was not recommended as a therapy in malignant pleural mesothelioma patients (Krug et al 2015). Another small phase II trial (conducted on thirtee ...
Apolipoprotein A5, a Newly Identified Gene That Affects Plasma
... Recent accomplishments by the Human Genome Project have facilitated genome-wide strategies to uncover functional regions of the mammalian genome. With the increasing availability of genomic sequences from multiple species, comparative genomic approaches have proven to be a powerful means for annotat ...
... Recent accomplishments by the Human Genome Project have facilitated genome-wide strategies to uncover functional regions of the mammalian genome. With the increasing availability of genomic sequences from multiple species, comparative genomic approaches have proven to be a powerful means for annotat ...
Apolipoprotein A5, a Newly Identified Gene That Affects Plasma
... Recent accomplishments by the Human Genome Project have facilitated genome-wide strategies to uncover functional regions of the mammalian genome. With the increasing availability of genomic sequences from multiple species, comparative genomic approaches have proven to be a powerful means for annotat ...
... Recent accomplishments by the Human Genome Project have facilitated genome-wide strategies to uncover functional regions of the mammalian genome. With the increasing availability of genomic sequences from multiple species, comparative genomic approaches have proven to be a powerful means for annotat ...
article ()
... genomes: no PLC are observed for the latter in the sIilall-scale regime where uncorrelated Brownian motion-like beqavior with H = 1/2 is observed (Figs. 2(b) and 3(b)). As discussed in previous works [5, 6, 9)0, 13, 18), separate analyses of coding and non-coding eucaryotic DNA walks actually show t ...
... genomes: no PLC are observed for the latter in the sIilall-scale regime where uncorrelated Brownian motion-like beqavior with H = 1/2 is observed (Figs. 2(b) and 3(b)). As discussed in previous works [5, 6, 9)0, 13, 18), separate analyses of coding and non-coding eucaryotic DNA walks actually show t ...
Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning
... seven-pass cadherin (Celsr) that is homologous to the Drosophila planar cell polarity (PCP) protein Flamingo/ Starry night (Fmi/Stan; Strutt and Strutt, ...
... seven-pass cadherin (Celsr) that is homologous to the Drosophila planar cell polarity (PCP) protein Flamingo/ Starry night (Fmi/Stan; Strutt and Strutt, ...
Computational Diagnosis - Computational Diagnostics Group
... - We combine consistently up and down regulated genes into signatures ...
... - We combine consistently up and down regulated genes into signatures ...
Computational Diagnosis
... - We combine consistently up and down regulated genes into signatures ...
... - We combine consistently up and down regulated genes into signatures ...
1. Introduction to Molecular Biology
... clustering of gene expression & sequence analysis) and finding transcription factors that bind to the corresponding promoters (through structural/sequence analysis) EECS 600: Systems Biology & Bioinformatics ...
... clustering of gene expression & sequence analysis) and finding transcription factors that bind to the corresponding promoters (through structural/sequence analysis) EECS 600: Systems Biology & Bioinformatics ...
Expanding the `central dogma`: the regulatory role of
... environmental factors can differentially express disease due to the presence or absence of correct imprinting.34 Hence, epigenetic effects may eventually help explain the complex roles of environment and inheritance in the etiology of schizophrenia. RNA mechanisms may be involved in epigenetic gene ...
... environmental factors can differentially express disease due to the presence or absence of correct imprinting.34 Hence, epigenetic effects may eventually help explain the complex roles of environment and inheritance in the etiology of schizophrenia. RNA mechanisms may be involved in epigenetic gene ...
1. Introduction to Molecular Biology
... clustering of gene expression & sequence analysis) and finding transcription factors that bind to the corresponding promoters (through structural/sequence analysis) EECS 600: Systems Biology & Bioinformatics ...
... clustering of gene expression & sequence analysis) and finding transcription factors that bind to the corresponding promoters (through structural/sequence analysis) EECS 600: Systems Biology & Bioinformatics ...
Wings, Horns, and Butterfly Eyespots: How Do Complex Traits Evolve?
... CREs that drive gene expression in context 1 are unable to do so in context 2 (Figure 2C). Additional CREs have to evolve de novo, probably one at a time, in order to rebuild the same network in tissue 2. In this scenario we do not expect to find pleiotropic CREs. ...
... CREs that drive gene expression in context 1 are unable to do so in context 2 (Figure 2C). Additional CREs have to evolve de novo, probably one at a time, in order to rebuild the same network in tissue 2. In this scenario we do not expect to find pleiotropic CREs. ...