Title PPAR interprets a chromatin signature of - DR-NTU
... Epigenetic post-transcriptional modifications of histone tails are thought to help in coordinating gene expression during development. An epigenetic signature is set in pluripotent cells and interpreted later at the onset of differentiation. In pluripotent cells, epigenetic marks normally associated ...
... Epigenetic post-transcriptional modifications of histone tails are thought to help in coordinating gene expression during development. An epigenetic signature is set in pluripotent cells and interpreted later at the onset of differentiation. In pluripotent cells, epigenetic marks normally associated ...
A Hybrid Knowledge-Driver Approach to Clustering Gene
... The main limitation of many gene expression analytic approaches is the fact that they do not successfully incorporate domain knowledge about the genes into the actual process, compromising the quality of the results obtained. Once the clustering algorithm has terminated, the challenge is to validate ...
... The main limitation of many gene expression analytic approaches is the fact that they do not successfully incorporate domain knowledge about the genes into the actual process, compromising the quality of the results obtained. Once the clustering algorithm has terminated, the challenge is to validate ...
High efficiency, site-specific excision of a marker gene by the phage
... of a speci®c gene. Insertion of a transgene into random or non-homologous chromosome regions introduces experimental variation due to position effects. The local environment of the insertion site may contain enhancer or silencing DNA sequences (3) or chromatin domains (4) that modify the expression ...
... of a speci®c gene. Insertion of a transgene into random or non-homologous chromosome regions introduces experimental variation due to position effects. The local environment of the insertion site may contain enhancer or silencing DNA sequences (3) or chromatin domains (4) that modify the expression ...
The Making of the Fittest: Evolving Switches, Evolving Bodies
... development raises chicken-or-egg questions. Although the development of a complex animal from a single cell is not fully understood, great progress has been made in recent decades to understand how different sets of genes move the development of an embryo through different stages to maturity. These ...
... development raises chicken-or-egg questions. Although the development of a complex animal from a single cell is not fully understood, great progress has been made in recent decades to understand how different sets of genes move the development of an embryo through different stages to maturity. These ...
Pseudogene function: regulation of gene expression
... several potential regulatory roles. The production of antisense transcripts from a TOP1 pseudogene was the first example of a naturally occurring antisense RNA transcript produced from a pseudogene…This study serves to emphasize not only the need to examine pseudogenes as potential active or regulato ...
... several potential regulatory roles. The production of antisense transcripts from a TOP1 pseudogene was the first example of a naturally occurring antisense RNA transcript produced from a pseudogene…This study serves to emphasize not only the need to examine pseudogenes as potential active or regulato ...
Characterization of Two ENU-Induced Mutations Affecting Mouse
... deformities in mice. The genes underlying these new ENU-derived mutants have previously been associated with skeletal abnormalities in both mice and humans, and thus serve as excellent tools for the study of the human skeleton and its development. The Skm1 mutation lies within the Npr3 gene coding f ...
... deformities in mice. The genes underlying these new ENU-derived mutants have previously been associated with skeletal abnormalities in both mice and humans, and thus serve as excellent tools for the study of the human skeleton and its development. The Skm1 mutation lies within the Npr3 gene coding f ...
2.4.databases_ensembl - T
... Tiny villages of Hobbits actually live in our DNA and produce minute quantities of wool -- which we've been ignorantly referring to as "navel lint" and throwing away for centuries. It's nearly impossible to re-fold it along the original creases. Beer-drinking gene conveniently located next to bathro ...
... Tiny villages of Hobbits actually live in our DNA and produce minute quantities of wool -- which we've been ignorantly referring to as "navel lint" and throwing away for centuries. It's nearly impossible to re-fold it along the original creases. Beer-drinking gene conveniently located next to bathro ...
Identification of Genes Related to Parkinson`s
... retard this process. Using an analysis of ESTs frequency, it was possible to identify a large number of genes related to human PD. These new genes, MBP, PBP, GNAS, SPP1 and TUBA3 in particular, represent potential biomarkers for PD and could serve as useful targets for elucidating the molecular mech ...
... retard this process. Using an analysis of ESTs frequency, it was possible to identify a large number of genes related to human PD. These new genes, MBP, PBP, GNAS, SPP1 and TUBA3 in particular, represent potential biomarkers for PD and could serve as useful targets for elucidating the molecular mech ...
Transvection in 2012: Site-Specific Transgenes Reveal a
... Southworth 2002). Such trans-regulatory interactions were first reported by Ed Lewis (Lewis 1954) who found that allelic complementation between particular mutations within the bithorax complex did not occur when the pairing of homologous chromosomes was disrupted. He called this pairing-dependent in ...
... Southworth 2002). Such trans-regulatory interactions were first reported by Ed Lewis (Lewis 1954) who found that allelic complementation between particular mutations within the bithorax complex did not occur when the pairing of homologous chromosomes was disrupted. He called this pairing-dependent in ...
Mining Gene Regulatory Networks and Microarray Data: The
... knowledge integration, and new tools to analyze and mine clinicogenomic data at all levels (gene, protein, molecular pathway, tissue, individual and population). Current post-genomics bioinformatics research seeks for methods that not only combine the information from dispersed and heterogeneous dat ...
... knowledge integration, and new tools to analyze and mine clinicogenomic data at all levels (gene, protein, molecular pathway, tissue, individual and population). Current post-genomics bioinformatics research seeks for methods that not only combine the information from dispersed and heterogeneous dat ...
Appearances can be deceiving: phenotypes of
... and Myf5, the individual knockouts have some differences—Myf5-null mice have abnormal rib development [33] and delayed trunk muscle development while MyoD-null mice have delayed limb and brachial arch muscle development [38]. There are various criteria that must be met for such compensation to occur ...
... and Myf5, the individual knockouts have some differences—Myf5-null mice have abnormal rib development [33] and delayed trunk muscle development while MyoD-null mice have delayed limb and brachial arch muscle development [38]. There are various criteria that must be met for such compensation to occur ...
classification
... This category includes any combination of alterations in the sequence (mutation) or expression of more than one gene/gene product. This category can therefore cover any of the IMP experiments that are done in a non-wild-type background, although we prefer to use it only when all mutations are docume ...
... This category includes any combination of alterations in the sequence (mutation) or expression of more than one gene/gene product. This category can therefore cover any of the IMP experiments that are done in a non-wild-type background, although we prefer to use it only when all mutations are docume ...
A molecular probe for Basidiomycota: the spermidine
... the fragments (around 1300 bp) coincided with the expected values. On the other hand, and as expected, no such amplification occurred when DNA from Ascomycota or Zygomycota species was used as template (Fig. 1b). The PCR products corresponding to the Basidiomycota species analyzed in this work were ...
... the fragments (around 1300 bp) coincided with the expected values. On the other hand, and as expected, no such amplification occurred when DNA from Ascomycota or Zygomycota species was used as template (Fig. 1b). The PCR products corresponding to the Basidiomycota species analyzed in this work were ...
The Diabetes-Prone BB Rat Carries a Frameshift Mutation in Ian4, a
... mismatch. We therefore decided to verify the lymphopenic phenotype and marker genotyping on the same frozen samples. For lymphopenia detection, we chose to perform quantitative RT-PCR for Cd8b levels in the spleen because the number of CD8-positive T-cells is severely reduced in lymphopenic rats (3) ...
... mismatch. We therefore decided to verify the lymphopenic phenotype and marker genotyping on the same frozen samples. For lymphopenia detection, we chose to perform quantitative RT-PCR for Cd8b levels in the spleen because the number of CD8-positive T-cells is severely reduced in lymphopenic rats (3) ...
The Concept of the Gene in Development and Evolution
... cases in which polypeptides are very different, an indicator of functional divergence, some authors recommend subdividing a site of expression into separate genes (Alberts et al. 1994). How different do the polypeptides have to be to split the locus into more than one gene? Molecular biologists do n ...
... cases in which polypeptides are very different, an indicator of functional divergence, some authors recommend subdividing a site of expression into separate genes (Alberts et al. 1994). How different do the polypeptides have to be to split the locus into more than one gene? Molecular biologists do n ...
The amdR product and a CCAAT-binding factor
... 3-galactosidase (9, M.J.H., unpublished data). These copies are integrated at sites other than the amdR locus, leaving the resident amdR gene intact. Gel mobility shift assays were performed on nuclear extracts from this strain and band (b) was detected as in the wild-type strain. In addition, howev ...
... 3-galactosidase (9, M.J.H., unpublished data). These copies are integrated at sites other than the amdR locus, leaving the resident amdR gene intact. Gel mobility shift assays were performed on nuclear extracts from this strain and band (b) was detected as in the wild-type strain. In addition, howev ...
ERF/AP2 Subfamily A3 and ER/AP2 Subfamily A6 Genes
... General Seed Coat/ Globular Stage General Seed coat/ Heart stage General seedcoat/ pre-globular stage ...
... General Seed Coat/ Globular Stage General Seed coat/ Heart stage General seedcoat/ pre-globular stage ...
Seed Germination Multiplexed Quantitative Gene Expression
... against internal reference genes the expression values are comparable. Once the data are normalized the values for each gene are similar regardless of concentration of the attenuated gene, and the values for a given gene are the same between any two capillaries (Figure 10). Thus, we conclude that at ...
... against internal reference genes the expression values are comparable. Once the data are normalized the values for each gene are similar regardless of concentration of the attenuated gene, and the values for a given gene are the same between any two capillaries (Figure 10). Thus, we conclude that at ...
ppt檔案
... The versions of for in these species affect the level of PKG The genes are orthologues - they descended from the same ancestral gene and have the same function But, for and PKG affects foraging through different mechanisms and may be regulated differently in species ...
... The versions of for in these species affect the level of PKG The genes are orthologues - they descended from the same ancestral gene and have the same function But, for and PKG affects foraging through different mechanisms and may be regulated differently in species ...
The tumor pathology of Genetically Engineered Mice: a new
... but with: a. an increased nuclear pleomorphism and level of differentiation b. a clearly differentiation in a glandular pattern c. an orientation to neuroendocrine pattern d. a characteristic nuclear pink granules T/F: The levels of expression of most oncogenic transgenes are related to the kinetics ...
... but with: a. an increased nuclear pleomorphism and level of differentiation b. a clearly differentiation in a glandular pattern c. an orientation to neuroendocrine pattern d. a characteristic nuclear pink granules T/F: The levels of expression of most oncogenic transgenes are related to the kinetics ...
The construction system of the brain References Rapid response
... Kirwan et al. 2008). It has been suggested that discrepancies between studies of remote episodic memory in hippocampal-damaged patients (Bayley et al. 2003) might be accounted for by differences in the quality or richness of the recollective experience (Gilboa et al. 2004), a feature that is not alw ...
... Kirwan et al. 2008). It has been suggested that discrepancies between studies of remote episodic memory in hippocampal-damaged patients (Bayley et al. 2003) might be accounted for by differences in the quality or richness of the recollective experience (Gilboa et al. 2004), a feature that is not alw ...
Regulation
... lactose, derepresses the operon by inactivating the repressor. In this way, the enzymes for lactose utilization are induced. ...
... lactose, derepresses the operon by inactivating the repressor. In this way, the enzymes for lactose utilization are induced. ...
Differential activity of Rickettsia rickettsii ompA and ompB promoter
... homology within their respective C-terminal 320 amino acids ( > 36% identity), a region that may include a membrane anchor (Hackstadt e t al., 1992) in the last 10 amino acids of each protein. It appears that in the case of rOmpB, a precursor form of the protein is cleaved to yield a 135 kDa N-termi ...
... homology within their respective C-terminal 320 amino acids ( > 36% identity), a region that may include a membrane anchor (Hackstadt e t al., 1992) in the last 10 amino acids of each protein. It appears that in the case of rOmpB, a precursor form of the protein is cleaved to yield a 135 kDa N-termi ...
B Supplementary Figure 2
... Supplementary FIG. 2. Quantitative RT-PCR analysis of expression levels of flowering genes in the ZCE1 RNAi lines. Quantitative RT-PCR analysis shows the transcript levels of FLK (A) and FLC (B) upon cis-CA and trans-CA treatment, respectively. FLK is a positive regulator of flowering via suppressin ...
... Supplementary FIG. 2. Quantitative RT-PCR analysis of expression levels of flowering genes in the ZCE1 RNAi lines. Quantitative RT-PCR analysis shows the transcript levels of FLK (A) and FLC (B) upon cis-CA and trans-CA treatment, respectively. FLK is a positive regulator of flowering via suppressin ...