Evolution of cis-regulatory elements in duplicated genes of yeast
... expression divergence in yeast. Moreover, we found some evidence for the action of positive selection on cisregulatory motifs after gene duplication. These results suggest that the evolution of functional novelty has a substantial role in yeast duplicate gene evolution. Gene expression changes are r ...
... expression divergence in yeast. Moreover, we found some evidence for the action of positive selection on cisregulatory motifs after gene duplication. These results suggest that the evolution of functional novelty has a substantial role in yeast duplicate gene evolution. Gene expression changes are r ...
An Arabidopsis Mutant with a Reduced Leve1 of cabl40 RNA 1s a
... DMA Gel Blot Analysis of the let Mutant a crossover between the marker and let. Analysis of F3 lines showed close linkage of let to the brevipedicellus (bp) marker on chromosome 4. The F3 progeny from 55 individual F2 bp lines from W8 (bp, eceriferum-2 [cer2], apetala-2 [ap2]) x let demonstrated tha ...
... DMA Gel Blot Analysis of the let Mutant a crossover between the marker and let. Analysis of F3 lines showed close linkage of let to the brevipedicellus (bp) marker on chromosome 4. The F3 progeny from 55 individual F2 bp lines from W8 (bp, eceriferum-2 [cer2], apetala-2 [ap2]) x let demonstrated tha ...
A haploid-specific transcriptional response to
... compared with the total number of genes showing variation of expression in each mutant. Only mutants giving a P > 0.005 in a hypergeometric test were considered (listed in Supplementary Table S2). Analysis of the molecular functions affected in mutants displaying specific HS-IR gene expression chang ...
... compared with the total number of genes showing variation of expression in each mutant. Only mutants giving a P > 0.005 in a hypergeometric test were considered (listed in Supplementary Table S2). Analysis of the molecular functions affected in mutants displaying specific HS-IR gene expression chang ...
Functional significance of the discordance between
... of integrated biological changes in cardiac myocyte size and function, as well as changes in LV structure and organization that allow for normalization of the LV end-diastolic pressure–volume (LVEDP-volume) relationship (reviewed in ref. 3). Although many of the individual components of reverse LV r ...
... of integrated biological changes in cardiac myocyte size and function, as well as changes in LV structure and organization that allow for normalization of the LV end-diastolic pressure–volume (LVEDP-volume) relationship (reviewed in ref. 3). Although many of the individual components of reverse LV r ...
The riboswitch control of bacterial metabolism
... A phylogenetic comparative analysis has shown that all thi-box sequences from various bacteria species are folded into similar hairpin structures [20,21]. The detailed functional analysis of the thi leader RNA box of the thiCOGE operon from R. etli revealed that repression by thiamin is a post-trans ...
... A phylogenetic comparative analysis has shown that all thi-box sequences from various bacteria species are folded into similar hairpin structures [20,21]. The detailed functional analysis of the thi leader RNA box of the thiCOGE operon from R. etli revealed that repression by thiamin is a post-trans ...
How the hippocampus preserves order: the role of
... nonhuman animals. These studies offer the unique ability to directly record neuronal activity from healthy tissue as well as create focal lesions to assess the necessity of a region for a behavioral task. Thus, we provide some discussion of this here but refer readers to other recent reviews for mor ...
... nonhuman animals. These studies offer the unique ability to directly record neuronal activity from healthy tissue as well as create focal lesions to assess the necessity of a region for a behavioral task. Thus, we provide some discussion of this here but refer readers to other recent reviews for mor ...
Synthetic Interactions
... Indeed snf1 has several functions (targeting substrates, response to stress, regulation of filamentations etc…) Dudely & Church 2005 ...
... Indeed snf1 has several functions (targeting substrates, response to stress, regulation of filamentations etc…) Dudely & Church 2005 ...
pdf
... Promoters contain binding sites for nuclear proteins, but which of these binding sites have a function in gene expression? This requires a genetic approach for an answer. 1. Use of "surrogate genetics" to define the promoter a. In vitro mutagenesis (deletions or point mutations) (1) Mutations of the ...
... Promoters contain binding sites for nuclear proteins, but which of these binding sites have a function in gene expression? This requires a genetic approach for an answer. 1. Use of "surrogate genetics" to define the promoter a. In vitro mutagenesis (deletions or point mutations) (1) Mutations of the ...
ppt - Chair of Computational Biology
... 57 out of 155 unique proteins bind to ≤ 5 promoters in at least one condition. 17 did not significantly bind to any promoters under any condition tested. In contrast, several TFs have hundreds of promoter targets. These TFs include the general regulatory factors (GRFs), which play a global role in t ...
... 57 out of 155 unique proteins bind to ≤ 5 promoters in at least one condition. 17 did not significantly bind to any promoters under any condition tested. In contrast, several TFs have hundreds of promoter targets. These TFs include the general regulatory factors (GRFs), which play a global role in t ...
word
... interested in cell growth and proliferation patterns during seed development and how the different parts that comprise a seed coordinate their development. Research from many groups has shown that epigenetic regulation plays an import role during seed development. Among other epigenetic mechanisms i ...
... interested in cell growth and proliferation patterns during seed development and how the different parts that comprise a seed coordinate their development. Research from many groups has shown that epigenetic regulation plays an import role during seed development. Among other epigenetic mechanisms i ...
length of exons and introns in genes of some human chromosomes
... The greatest average density of genes/Mbp has chromosome 19 and two gene groups were formed a high gene density (Table 1). In both gene groups the relationship between sum of exon lengths and number of intron in genes was similar and was characterized by high correlation coefficients. Chromosome 13 ...
... The greatest average density of genes/Mbp has chromosome 19 and two gene groups were formed a high gene density (Table 1). In both gene groups the relationship between sum of exon lengths and number of intron in genes was similar and was characterized by high correlation coefficients. Chromosome 13 ...
Recurrent Tandem Gene Duplication Gave Rise
... It is well recognized that gene duplication is prevalent in eukaryotes. Genomic analyses of model organisms have shown that over one-third of all protein-coding genes belong to multigene families (Rubin et al. 2000; Kent et al. 2003). The mechanisms of gene duplication can be classified based on its ...
... It is well recognized that gene duplication is prevalent in eukaryotes. Genomic analyses of model organisms have shown that over one-third of all protein-coding genes belong to multigene families (Rubin et al. 2000; Kent et al. 2003). The mechanisms of gene duplication can be classified based on its ...
The glpP and glpF genes of the glycerol regulon in
... The Bacillus subtilis glpPFKD region contains genes essential for growth on glycerol or glycerol 3-phosphate (G3P). The nucleotide sequence of glpP encoding a regulatory protein and the previously unidentified glpF encoding the glycerol uptake facilitator was determined. glpF is located immediately ...
... The Bacillus subtilis glpPFKD region contains genes essential for growth on glycerol or glycerol 3-phosphate (G3P). The nucleotide sequence of glpP encoding a regulatory protein and the previously unidentified glpF encoding the glycerol uptake facilitator was determined. glpF is located immediately ...
as Microsoft Word - Edinburgh Research Explorer
... of the electrophysiological abnormalities of the gastrointestinal tract of cystic fibrosis patients. An elevated nasal PD is recognised as one of the hallmarks of cystic fibrosis16 and is used in the clinical diagnosis of patients. Human nasal epithelium predominantly absorbs sodium in the resting s ...
... of the electrophysiological abnormalities of the gastrointestinal tract of cystic fibrosis patients. An elevated nasal PD is recognised as one of the hallmarks of cystic fibrosis16 and is used in the clinical diagnosis of patients. Human nasal epithelium predominantly absorbs sodium in the resting s ...
NOBA Memory (Encoding, Storage, Retrieval)
... tragedies, such as terrorist attacks, often create vivid memories in those who witnessed them. But even those of us not directly involved in such events may have vivid memories of them, including memories of first hearing about them. For example, many people are able to recall their exact physical l ...
... tragedies, such as terrorist attacks, often create vivid memories in those who witnessed them. But even those of us not directly involved in such events may have vivid memories of them, including memories of first hearing about them. For example, many people are able to recall their exact physical l ...
reproductive cell fate transition in plants - Development
... Histone variants are dynamically exchanged in differentiating MMCs Linker histones (H1) are essential modulators of chromatin compaction through binding to the linker DNA and the core nucleosome, thereby stabilizing higher-order chromatin structure (Robinson and Rhodes, 2006). The Arabidopsis genome ...
... Histone variants are dynamically exchanged in differentiating MMCs Linker histones (H1) are essential modulators of chromatin compaction through binding to the linker DNA and the core nucleosome, thereby stabilizing higher-order chromatin structure (Robinson and Rhodes, 2006). The Arabidopsis genome ...
... missing heritability, geneticists also call for the rescue of the concept of gene-gene epistatic interrelations [70] that would increase significantly the role of found gene variants [71, 72], a hypothesis that remains yet impossible to prove but has a lot of biological rationale. Epistatic interact ...
Exam Answer Keys
... 1. You are studying how yeast cells grow on sucrose and you find that both sucrose and glucose regulate expression of the SUC1 gene, which encodes an enzyme for sucrose breakdown. SUC1 is not expressed in cells grown without sucrose, but is induced when sucrose is added to the growth medium. In cell ...
... 1. You are studying how yeast cells grow on sucrose and you find that both sucrose and glucose regulate expression of the SUC1 gene, which encodes an enzyme for sucrose breakdown. SUC1 is not expressed in cells grown without sucrose, but is induced when sucrose is added to the growth medium. In cell ...
Modified `one amino acid-one codon` engineering of high GC
... cloned a fully synthetic, low GC content, low mRNA secondary structure taqIIRM, codon-optimized gene under a bacteriophage lambda (λ) PR promoter. Codon usage based on a modified ‘one amino acid–one codon’ strategy, weighted towards low GC content codons, resulted in approximately 10-fold higher exp ...
... cloned a fully synthetic, low GC content, low mRNA secondary structure taqIIRM, codon-optimized gene under a bacteriophage lambda (λ) PR promoter. Codon usage based on a modified ‘one amino acid–one codon’ strategy, weighted towards low GC content codons, resulted in approximately 10-fold higher exp ...
BMC Developmental Biology
... Eya3 shows a complex expression pattern during embryonic development. The expression pattern of Eya3 is identical, if analyzed by in-situ hybridization in wild-type embryos or by β-Gal expression in Eya3-/- mutant mice; data gathered from β-Gal staining of mutant embryos (Fig. 3a) demonstrated an ex ...
... Eya3 shows a complex expression pattern during embryonic development. The expression pattern of Eya3 is identical, if analyzed by in-situ hybridization in wild-type embryos or by β-Gal expression in Eya3-/- mutant mice; data gathered from β-Gal staining of mutant embryos (Fig. 3a) demonstrated an ex ...
Genes and MS
... It's not yet clear exactly what the relationship is between levels of vitamin D, genes and MS. It could be one of many factors involved in someone developing the condition. Gene therapy In some health conditions, only one gene is responsible. It might be possible to alter this gene and prevent or cu ...
... It's not yet clear exactly what the relationship is between levels of vitamin D, genes and MS. It could be one of many factors involved in someone developing the condition. Gene therapy In some health conditions, only one gene is responsible. It might be possible to alter this gene and prevent or cu ...
pdf
... Figure 2 | Conjunctiveness and hubness in the hippocampus. (a) Representational similarity analysis (RSA) logic. Left: associative similarity contrast, with expected high regional representational similarity for comparisons of the same association, and low similarity for comparisons of different ass ...
... Figure 2 | Conjunctiveness and hubness in the hippocampus. (a) Representational similarity analysis (RSA) logic. Left: associative similarity contrast, with expected high regional representational similarity for comparisons of the same association, and low similarity for comparisons of different ass ...
The making of the Fittest: Natural Selection and
... activator that binds the pelvic switch) is also under regulatory control. Thinking about development raises chicken-oregg questions. Although the development of a complex animal from a single cell is not fully understood, great progress has been made in recent decades to understand how different set ...
... activator that binds the pelvic switch) is also under regulatory control. Thinking about development raises chicken-oregg questions. Although the development of a complex animal from a single cell is not fully understood, great progress has been made in recent decades to understand how different set ...
Distinct effects of 11q aberrations on neuroblastoma with
... Supplementary table 1: Characteristics of patients and tumour samples of the four clinicogenetic subgroups normal_fav (A), normal_unfav (B), del11q_fav (C) and del11q_unfav (D). Indicated are the stage of disease according to INSS, the age at diagnosis (days), the genomic MYCN, 1p, 11q and 3p status ...
... Supplementary table 1: Characteristics of patients and tumour samples of the four clinicogenetic subgroups normal_fav (A), normal_unfav (B), del11q_fav (C) and del11q_unfav (D). Indicated are the stage of disease according to INSS, the age at diagnosis (days), the genomic MYCN, 1p, 11q and 3p status ...
reproductive cell fate transition in plants - Development
... is crucial for subsequent development. In plants, genetic evidence ...
... is crucial for subsequent development. In plants, genetic evidence ...